Caitlin Colling,Clifford J Rosen
Caitlin Colling
Type 2 diabetes mellitus (T2DM) is defined by a common end point: hyperglycemia diagnosed by fasting plasma glucose, plasma glucose during an oral glucose tolerance test, or hemoglobin A1c without autoimmune β-cell destruction.1 Historical...
Suiane Costa Negreiros,Giselle Maria Rachid Viana
Suiane Costa Negreiros
Antimalarial Research in the AmazonMany patients who receive treatment for vivax malaria in the Americas present with recurrent infection within six months after completing treatment. This raises an important question: Does higher-dose prim...
C Maxwell Shannon,Roberto Cavazos,Cecilia Cai et al.
C Maxwell Shannon et al.
A 48-Year-Old Man with Fevers and Weight Loss48-year-old man presented for evaluation of fevers, night sweats, and a 20-pound unintentional weight loss over 3 months. He also had a dry cough over the same time, without dyspnea, chest discom...
Do Anticoagulants Preserve Function and Quality of Life in Older Adults with Atrial Fibrillation? [0.03%]
抗凝剂能否保持老年人群心房纤颤的功能和生活质量？
Sachin J Shah,Kenneth E Covinsky
Sachin J Shah
Anticoagulants in Older Adults with Atrial FibrillationAn 82-year-old woman with hypertension and diabetes is seen in the clinic for newly diagnosed atrial fibrillation. She uses a walker and fell twice last year. She completes activities o...
Leveraging Artificial Intelligence to Improve Pregnancy Dating in Low-Resource Settings [0.03%]
利用人工智能改善资源匮乏地区的妊娠期评估
Blair J Wylie,Anne C C Lee
Blair J Wylie
For practicing obstetricians and pediatricians, accurate gestational age (GA) is a cornerstone of quality care during pregnancy and the newborn period. GA determines prenatal management decisions, such as eligibility for antenatal glucocort...
Lorraine D Cornwell,Robert Taylor Ripley
Lorraine D Cornwell
Thoracoscopic Lobectomy Blooms in the VIOLET TrialLung cancer is currently the deadliest malignancy worldwide. Societal stigma, poor survival rates, and comparatively low funding for lung cancer research all contribute to lingering therapeu...
Tyler D Bold
Tyler D Bold
Deja vu is the sensation of having a recurrent experience. Within a year after an initial urinary tract infection (UTI), up to 30% of women will experience a recurrence of UTI symptoms.1 A smaller group of women (1%) may experience frequent...
Siri Kadire,Charles C Hardin,Katherine S Takvorian et al.
Siri Kadire et al.
Is Noninferior Not Inferior? What is a non-inferiority trial margin? To answer this, ask whether you have ever weighed a tradeoff between the best version of something and an acceptable alternative. Restated, in a choice between two decisio...
Bentracimab for Ticagrelor Reversal in Patients Undergoing Urgent Surgery [0.03%]
Bentracimab用于紧急手术患者的替卡格雷逆转
Deepak L Bhatt,Charles V Pollack,C David Mazer et al.
Deepak L Bhatt et al.
BACKGROUND: Ticagrelor is a reversible oral P2Y12 platelet inhibitor used to treat patients with acute coronary syndromes, prior myocardial infarction, high-risk coronary artery disease, transient ischemic attack, or ischemic stroke. A heal...
Rebecca E Berger
Rebecca E Berger
Prophylaxis and Recurrent Clostridioides difficileA 68-year-old woman is admitted with pyelonephritis. Two months earlier, she had been treated for pneumonia and subsequently developed Clostridioides difficile colitis, which resolved with 1...