Jiaojiao Liu,Shuk Hang Li,Naiqing Ye et al.
Jiaojiao Liu et al.
AbstractA new H3N2 variant (named subclade K) possesses several key hemagglutinin substitutions and is circulating widely during the 2025-2026 influenza season. We sought to determine whether the 2025-2026 seasonal influenza vaccine elicits...
Multistate Infant Botulism Outbreak Associated with Powdered Infant Formula [0.03%]
与婴儿配方奶粉相关的多州婴儿肉毒杆菌病暴发事件
Connie H Chung,Jason R Barash,Jacquelin L Castonguay et al.
Connie H Chung et al.
AbstractThis report details the identification of an outbreak of infant botulism linked to powdered infant formula in the United States. In October 2025, the Infant Botulism Treatment and Prevention Program, California Department of Public ...
Valproate Use by Fathers and Risk of Neurodevelopmental Disorders in Children [0.03%]
父亲使用丙戊酸盐与儿童神经发育障碍的风险关联性研究
Lin-Chieh Meng,Marleen M H J van Gelder,Hui-Min Chuang et al.
Lin-Chieh Meng et al.
Background: There is concern about the increased risk of neurodevelopmental disorders (NDDs) among offspring of fathers taking valproate within 90 days before conception. ...
Feasibility Trial of Prolonged versus Single-Dose Challenge in Penicillin Allergy [0.03%]
长效与单剂量给药治疗青霉素过敏的可行性试验
Morgan Rose,Sara Vogrin,Elise A Mitri et al.
Morgan Rose et al.
Background: We aimed to evaluate the feasibility of conducting a multicenter, double-blind, placebo-controlled trial of prolonged (i.e., multidose) compared with single-dose amoxicillin challenge in patients with a histor...
Randomized Controlled Trial
NEJM evidence. 2026 Mar;5(3):EVIDoa2500038. DOI:10.1056/EVIDoa2500038 2026
Targeted Treatment of Moderate Hyponatremia in Hospitalized Patients - Helpful or Unnecessary? [0.03%]
中度低钠血症的靶向治疗——有益还是多余？
Alexander Kumachev,Thomas E MacMillan
Alexander Kumachev
Alena Annbalou Hasenburg,Axel Grothey
Alena Annbalou Hasenburg
Evaluating Noninferiority in Clinical Trials with a Hierarchical End Point [0.03%]
临床试验中含层次结构终点的非劣效评价方法研究
John Gregson,Bjorn Redfors,David J Cohen et al.
John Gregson et al.
AbstractThe win ratio is a method for analyzing a clinical hierarchy of outcomes. It is most commonly applied to randomized clinical trials to evaluate the superiority of an intervention versus the standard of care. Once an intervention is ...
Evidence against Neurodevelopmental Risks for Children Whose Fathers Use Valproate [0.03%]
父亲使用丙戊酸对儿童神经发育风险的证据不足
Kimford J Meador
Kimford J Meador
Jonathan D Browne,Peter W Kaplan
Jonathan D Browne
AbstractMorning Report is a time-honored tradition where physicians-in-training present cases to their colleagues and clinical experts to collaboratively examine an interesting patient presentation. The Morning Report section seeks to carry...
Case Reports
NEJM evidence. 2026 Mar;5(3):EVIDmr2500286. DOI:10.1056/EVIDmr2500286 2026
Disclosure of Pregnancy-Related Privacy Risks in Clinical Research Post-Dobbs [0.03%]
多布斯裁决后临床研究中与怀孕相关的隐私风险披露
Ava Glazier,Willyanne DeCormier Plosky,Barbara E Bierer
Ava Glazier
AbstractInterventional clinical research often involves risks to participants of reproductive potential, requiring pregnancy testing, contraception, and reporting of incidental pregnancies. Since the Dobbs v. Jackson Women's Health Organiza...