The complex landscape of immune dysregulation in multisystem inflammatory syndrome in children with COVID-19 [0.03%]
儿童COVID-19多系统炎症综合征的免疫紊乱复杂图景
Jing Guo,Lie Wang
Jing Guo
The immune responses following SARS-CoV-2 infection in children are still under investigation. While coronavirus disease 2019 (COVID-19) is usually mild in the paediatric population, some children develop severe clinical manifestations or m...
Comparative dissection of transcriptional landscapes of human iPSC-NK differentiation and NK cell development [0.03%]
人iPSC-NK分化和NK细胞发育的转录景观解析
Li Zhang,Taylor M Weiskittel,Yuqing Zhu et al.
Li Zhang et al.
Clinical and preclinical research has demonstrated that iPSC-derived NK (iNK) cells have a high therapeutic potential, yet poor understanding of the detailed process of their differentiation in vitro and their counterpart cell development i...
Cell surface protein-protein interaction profiling for biological network analysis and novel target discovery [0.03%]
用于生物学网络分析和新型目标发现的细胞表面蛋白质-蛋白质相互作用图谱绘制法
Jiaojiao Chen,Maoxin Fang,Yuwei Li et al.
Jiaojiao Chen et al.
The secretome is composed of cell surface membrane proteins and extracellular secreted proteins that are synthesized via secretory machinery, accounting for approximately one-third of human protein-encoding genes and playing central roles i...
Research on the function of epigenetic regulation in the inflammation of non-alcoholic fatty liver disease [0.03%]
表观遗传调控在非酒精性脂肪肝病炎症作用的研究进展
Lin Sun,Zhensheng Yue,Lin Wang
Lin Sun
Nonalcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver condition, characterized by a spectrum that progresses from simple hepatic steatosis to nonalcoholic steatohepatitis, which may eventually lead to cirrhosis and he...
Jia-Yi Zhou,Ying Yang
Jia-Yi Zhou
Small-molecule activation of NAMPT as a potential neuroprotective strategy [0.03%]
小分子活化NAMPT作为潜在的神经保护策略
Xuanyu Gu,Hong Yao,Ilmin Kwon et al.
Xuanyu Gu et al.
Juli Bai,Feng Liu
Juli Bai
Macrophages are widely distributed in various metabolic tissues/organs and play an essential role in the immune regulation of metabolic homeostasis. Macrophages have two major functions: adaptive defenses against invading pathogens by trigg...
The potential effects of the United States abortion ruling on global embryo/foetal and stem cell research [0.03%]
美国关于堕胎判决对全球胚胎/胎儿和干细胞研究潜在影响的观点学派及评论文章标题梳理
Zhenyu Xiao,Jianwei Lv,Siqi Zhao et al.
Zhenyu Xiao et al.
Xuanxuan Zou,Xi Dai,Alexios-Fotios A Mentis et al.
Xuanxuan Zou et al.
NAD+ is critical for maintaining acetyl-CoA and H3K27ac in embryonic stem cells by Sirt1-dependent deacetylation of AceCS1 [0.03%]
烟酰胺腺嘌呤二核苷酸对胚胎干细胞组蛋白H3K27乙酰化和乙酰辅酶A的维持至关重要：Sirt1依赖性去乙酰化AceCS1的作用
Yi Wu,Yang Liu,Zhihong Hao et al.
Yi Wu et al.