Lysozyme alleviates DSS-induced colitis by modulating pro-inflammatory factors and NF-κB activation [0.03%]
溶菌酶通过调节促炎因子和NF-κB活化来缓解DSS诱导的结肠炎
Kai Wang,Lan Guo,Ting Wang et al.
Kai Wang et al.
Zhejun Ji,Guang-Hui Liu,Jing Qu
Zhejun Ji
Mitochondrial dysfunction is a hallmark of aging, characterized by a decline in mitochondrial biogenesis and quality control, compromised membrane integrity, elevated ROS production, damaged mitochondrial DNA (mtDNA), impaired mitochondrial...
A framework of biomarkers for visual system aging: a consensus statement by the Aging Biomarker Consortium [0.03%]
视觉系统老化生物标志物框架：老龄化生物标志物联盟共识声明
Aging Biomarker Consortium;Chao Ma,Boxin Geng,Yangqing Zhang et al.
Aging Biomarker Consortium;Chao Ma et al.
The visual system is essential for human perception, converting light signals into electrical impulses and transmitting them to the brain to process environmental information. As individuals age, their physiological functions gradually decl...
The new composition of circulating microvesicles: optimized protocols and reassessment of their characteristics and physiological functions [0.03%]
循环微囊的新组成：优化的协议及其特征和生理功能的再评估
Chen Zhang,Jiajia Hu,Yifan Shi et al.
Chen Zhang et al.
Microvesicles (MVs) have convenient clinical applications and play functional roles in cellular signal transduction. Although the clinical importance of MVs is being increasingly recognized, the current diversity of isolated protocols resul...
Reprogramming aging: genetically enhanced mesenchymal progenitor cells show systemic rejuvenation in primates [0.03%]
重编程衰老：遗传增强的间充质祖细胞在灵长类动物中表现出系统年轻化
Hongkun Wang,Yuanyuan Du
Hongkun Wang
Human iPSC-derived self-assembled cardiac organoids for evaluating drug developmental cardiotoxicity [0.03%]
人诱导多能干细胞来源的心肌器官芯片技术评估药物心脏毒性风险
Yi Xiao,Pengfei Xu,Jinmiao Bi et al.
Yi Xiao et al.
Haim Y Cohen,Vera Gorbunova,Steve Horvath et al.
Haim Y Cohen et al.
Jiyu Chen,Chang Liu,Yongqin Yu et al.
Jiyu Chen et al.
Adult ovarian tissues or biopsies isolated from patients prior to chemotherapy or irradiation can reconstitute ovarian functions when transplanted either in the abdomen or subcutaneously. Subcutaneously transplantation avoids invasive surge...
Function of hematopoiesis and bone marrow niche in inflammation and non-hematopoietic diseases [0.03%]
造血和骨髓生态位在炎症和非血液系统疾病中的作用
Yu-Xiang Wang,Zhao-Hua Deng,Yu-Yan Li et al.
Yu-Xiang Wang et al.
Hematopoiesis and the behavior of hematopoietic stem and progenitor cells (HSPCs) are regulated by the bone marrow niche. Here, we introduce the major niche cell types in bone marrow and their response to stress condition. We highlight the ...
Zixuan Hong,Yun Zhao,Sara Pahlavan et al.
Zixuan Hong et al.
Human pluripotent stem cells (hPSCs) hold great promise in regenerative medicine. However, immune rejections remain one of the major obstacles to stem cell therapy. Though conventional immunosuppressants are available in clinics, the side e...