HDAC8-selective inhibitor PCI-34051 protects against aortic dissection by attenuating ferroptosis of vascular smooth muscle cells [0.03%]
HDAC8特异性抑制剂PCI-34051通过减轻血管平滑肌细胞铁死亡保护小鼠免受主动脉夹层损害
Jiannan Ye,Juan Shi,Xin Yi et al.
Jiannan Ye et al.
Aortic dissection (AD) is a fatal emergency which lacks effective drug therapies. Previous studies demonstrated that histone deacetylase 8 (HDAC8) inhibition provides protective benefits in several cardiovascular diseases, including heart f...
The multistep progression of areca nut-induced oral cancer: a mechanistic roadmap from pathogenesis to precision therapy [0.03%]
从发病机制到精确诊疗的含羞草引起的口腔癌多步进展之路
Na Yu,Wenqiu Cai,Congyi Zhang et al.
Na Yu et al.
Areca nut is classified as a Group 1 carcinogen by the International Agency for Research on Cancer. It is a widely consumed psychoactive substance with profound cultural roots in regions including Hunan, Hainan, and Taiwan of China. Its key...
Salivary volatilome profiling in pediatric eosinophilic esophagitis: a pilot study on a non-invasive approach in clinical practice [0.03%]
儿童嗜酸细胞性食管炎唾液挥发性组分特征分析：临床实践中的无创性方法探索性研究
Rosamaria Capuano,Carla Petrella,Christian Barbato et al.
Rosamaria Capuano et al.
Eosinophilic esophagitis (EoE) is a chronic immune disease requiring repeated endoscopies for diagnosis and monitoring in children. Saliva represents a promising non-invasive biofluid, and volatile organic compounds (VOCs) may indicate dise...
Macrophage-directed T cell recruitment augments IFN-Mediated suppression of cardiac reprogramming in vivo [0.03%]
巨噬细胞募集T细胞增强IFN介导的心脏在体重编程抑制作用
Yihong Cai,Hao Wang,Junbo Yang et al.
Yihong Cai et al.
Single-cell analysis reveals essential lncRNAs regulating human trophoblast lineage differentiation [0.03%]
单细胞分析揭示长链非编码RNA调控人滋养层细胞分化的重要作用
Weiyi Zhang,Chunyan Le,Shanru Yi et al.
Weiyi Zhang et al.
The human placenta sustains pregnancy through intricate trophoblast lineage dynamics that are critical for fetal development and pregnancy success. While studies on protein-coding genes (PCGs) have advanced our understanding of placental bi...
Alexia D Defrancesco,Chenju Yi,Brian G Oliver et al.
Alexia D Defrancesco et al.
The immune effects of mesenchymal stem cell-based therapy in kidney diseases [0.03%]
基于间充质干细胞疗法的肾脏疾病的免疫效应
Yachao Li,Kuai Ma,Junyi Ren et al.
Yachao Li et al.
Natural compounds of medicinal plants as a source for novel anti-orthopoxvirus medications [0.03%]
医药植物中的天然化合物作为新型抗正痘病毒药物的来源
Eman A Makhlouf,Riham A El-Shiekh,Mona M Okba et al.
Eman A Makhlouf et al.
iPSC-derived breast cancer models: advancing the study of BRCA1-driven tumorigenesis [0.03%]
由诱导多能干细胞衍生的乳腺癌模型：推进BRCA1驱动的肿瘤发生的研究
Pengguihang Zeng,Zhuheng Zhang,Xinyi Liu et al.
Pengguihang Zeng et al.