Human oocyte microtubule organizing center: a newly identified driver for meiotic spindle assembly in female oocytes [0.03%]
人类卵细胞微管组织中心：女性卵子中有丝分裂纺锤体装配的新驱动因素
Jie Dong,Tianyu Wu,Qing Sang et al.
Jie Dong et al.
Xusheng Zhang,Xiwen Qin,Shuo Wang
Xusheng Zhang
Yonglin Wu,Miaomiao Pan,Zheng Zou et al.
Yonglin Wu et al.
A framework of biomarkers for brain aging: a consensus statement by the Aging Biomarker Consortium [0.03%]
脑衰老生物标志物的框架：老龄化生物标志物联盟共识声明
Aging Biomarker Consortium;Yu-Juan Jia,Jun Wang,Jun-Rong Ren et al.
Aging Biomarker Consortium;Yu-Juan Jia et al.
China and the world are facing severe population aging and an increasing burden of age-related diseases. Aging of the brain causes major age-related brain diseases, such as neurodegenerative diseases and stroke. Identifying biomarkers for t...
Guang-Hui Liu,Juan Carlos Izpisua Belmonte
Guang-Hui Liu
Yuanxin Yang,Xingyan Li,Tao Zhang et al.
Yuanxin Yang et al.
Aging is a natural process that is characterized by chronic, low-grade inflammation, which represents the primary risk factor in the pathogenesis of a variety of diseases, i.e. aging-related diseases. RIP kinases, in particular RIPK1 and RI...
Counter changes with changelessness: cope with SARS-CoV-2 immune evasion by targeting cryptic epitopes [0.03%]
应对新冠病毒免疫逃逸的一种策略：针对隐蔽性表位
Cheng Li,Tianlei Ying,Dimiter S Dimitrov et al.
Cheng Li et al.
Lipid nanoparticles for mRNA therapy: recent advances in targeted delivery [0.03%]
用于mRNA治疗的脂质纳米颗粒：靶向递送的最新进展
Tuo Wei,Wei Tao,Qiang Cheng
Tuo Wei
CRISPR/Cas9-mediated genetic correction reverses spinocerebellar ataxia 3 disease-associated phenotypes in differentiated cerebellar neurons [0.03%]
基于CRISPR/Cas9的基因纠正逆转小脑皮层神经元中脊髓小脑共济失调3号病相关表型
Guoxu Song,Yuying Ma,Xing Gao et al.
Guoxu Song et al.
The neurodegenerative disease spinocerebellar ataxia type 3 (SCA3; also called Machado-Joseph disease, MJD) is a trinucleotide repeat disorder caused by expansion of the CAG repeats in the ATXN3 gene. Here, we applied a CRISPR/Cas9-mediated...
4D live tracing reveals distinct movement trajectories of meiotic chromosomes [0.03%]
4D实时追踪揭示了减数分裂染色体的运动轨迹不同
Peng Xie,Shiqi Zhu,Jin Zhang et al.
Peng Xie et al.
Proper chromosome alignment at the spindle equator is a prerequisite for accurate chromosome segregation during cell division. However, the chromosome movement trajectories prior to alignment remain elusive. Here, we established a 4D imagin...