GlycoRNAs: more than the intersection of glycobiology and RNA biology [0.03%]
糖基RNA：不仅仅是糖生物学和RNA生物学的交集
Haidong Li,Ruijin Zhang,Runsheng Chen et al.
Haidong Li et al.
The evolution of ovarian somatic cells characterized by transcriptome and chromatin accessibility across rodents, monkeys, and humans [0.03%]
横跨啮齿目、灵长目和人类的卵巢间质细胞转录组及染色体可接近性特征演化研究
Qiancheng Zhang,Fengyuan Sun,Ruifeng Zhang et al.
Qiancheng Zhang et al.
The ovary plays a crucial role in the reproductive system of female mammals by producing mature oocytes through folliculogenesis. Non-human model organisms are extensively utilized in research on human ovarian biology, thus necessitating th...
Intestinal stem cells in intestinal homeostasis and colorectal tumorigenesis [0.03%]
肠干细胞在肠道稳态和结直肠肿瘤发生中的作用
Gaoli Shi,Yang Li,Haihong Shen et al.
Gaoli Shi et al.
Colorectal cancer (CRC), one of the most common tumors in the world, is generally proposed to be generated from intestinal stem cells (ISCs). Leucine-rich repeat-containing G protein-coupled receptor 5 (Lgr5)-positive ISCs are located at th...
Hang Zhang,Yuan Chang,Jiangping Song
Hang Zhang
Deciphering the dynamic single-cell transcriptional landscape in the ocular surface ectoderm differentiation system [0.03%]
破译眼表上皮细胞分化系统中动态单细胞转录组景观
Canwei Zhang,Zesong Lin,Yankun Yu et al.
Canwei Zhang et al.
The ocular surface ectoderm (OSE) is essential for the development of the ocular surface, yet the molecular mechanisms driving its differentiation are not fully understood. In this study, we used single-cell transcriptomic analysis to explo...
Integrated transcriptomic analysis reveals dysregulated immune infiltration and pro-inflammatory cytokines in the secretory endometrium of recurrent implantation failure patients [0.03%]
整合转录组分析揭示了复发性植入失败患者分泌期子宫内膜中免疫浸润和促炎细胞因子失调
Ping Zhou,Dan Mo,Hanji Huang et al.
Ping Zhou et al.
Recurrent implantation failure (RIF) is a leading impediment to assisted reproductive technology, yet the underlying pathogenesis of RIF remains elusive. Recent studies have sought to uncover novel biomarkers and etiological factors of RIF ...
Yuge Feng,Cong Su,Guobin Mao et al.
Yuge Feng et al.
In recent years, the world has faced significant challenges with the coronavirus disease 2019 (COVID-19) pandemic, as well as other infectious diseases such as Zika and Ebola. Furthermore, the rapid rise of non-communicable diseases such as...
Programmable G-to-Y base editing using engineered DNA glycosylase [0.03%]
利用工程DNA碱基切除修复途径实现G到Y的可编程碱基编辑器
Huawei Tong,Tong Li,Hui Yang
Huawei Tong
Carlos A Pinzón-Arteaga,Leqian Yu
Carlos A Pinzón-Arteaga
Deciphering microbiota-host interplay: bacterial metabolites and protein post-translational modifications [0.03%]
解读微生物组与宿主的相互作用：细菌代谢物和蛋白质翻译后修饰
Mingya Zhang,Sangkyu Lee,Min Huang et al.
Mingya Zhang et al.