Hang Zhang,Yuan Chang,Jiangping Song
Hang Zhang
Deciphering the dynamic single-cell transcriptional landscape in the ocular surface ectoderm differentiation system [0.03%]
破译眼表上皮细胞分化系统中动态单细胞转录组景观
Canwei Zhang,Zesong Lin,Yankun Yu et al.
Canwei Zhang et al.
The ocular surface ectoderm (OSE) is essential for the development of the ocular surface, yet the molecular mechanisms driving its differentiation are not fully understood. In this study, we used single-cell transcriptomic analysis to explo...
Integrated transcriptomic analysis reveals dysregulated immune infiltration and pro-inflammatory cytokines in the secretory endometrium of recurrent implantation failure patients [0.03%]
整合转录组分析揭示了复发性植入失败患者分泌期子宫内膜中免疫浸润和促炎细胞因子失调
Ping Zhou,Dan Mo,Hanji Huang et al.
Ping Zhou et al.
Recurrent implantation failure (RIF) is a leading impediment to assisted reproductive technology, yet the underlying pathogenesis of RIF remains elusive. Recent studies have sought to uncover novel biomarkers and etiological factors of RIF ...
Yuge Feng,Cong Su,Guobin Mao et al.
Yuge Feng et al.
In recent years, the world has faced significant challenges with the coronavirus disease 2019 (COVID-19) pandemic, as well as other infectious diseases such as Zika and Ebola. Furthermore, the rapid rise of non-communicable diseases such as...
Programmable G-to-Y base editing using engineered DNA glycosylase [0.03%]
利用工程DNA碱基切除修复途径实现G到Y的可编程碱基编辑器
Huawei Tong,Tong Li,Hui Yang
Huawei Tong
Carlos A Pinzón-Arteaga,Leqian Yu
Carlos A Pinzón-Arteaga
Deciphering microbiota-host interplay: bacterial metabolites and protein post-translational modifications [0.03%]
解读微生物组与宿主的相互作用：细菌代谢物和蛋白质翻译后修饰
Mingya Zhang,Sangkyu Lee,Min Huang et al.
Mingya Zhang et al.
Follicular fluid-derived exosomes rejuvenate ovarian aging through miR-320a-3p-mediated FOXQ1 inhibition [0.03%]
卵泡液衍生的外泌体通过miR-320a-3p介导的FOXQ1抑制作用来逆转卵巢衰老
Yu Liu,Hongbei Mu,Yu Chen et al.
Yu Liu et al.
Ovarian aging is mainly characterized by a progressive decline in oocyte quantity and quality, which ultimately leads to female infertility. Various therapies have been established to cope with ovarian aging, among which exosome-based thera...
Modeling antiviral response in the liver using human pluripotent stem cell-derived macrophages [0.03%]
采用人多能干细胞源巨噬细胞构建肝脏抗病毒反应模型
Yaxuan Zhang,Xingwu Zhang,Fuyu Duan et al.
Yaxuan Zhang et al.
Xudong Yao,Xiaojun Xia,David C Hay et al.
Xudong Yao et al.