Incidence and treatment of group A streptococcal infections during covid-19 pandemic and 2022 outbreak: retrospective cohort study in England using OpenSAFELY-TPP [0.03%]
英国开放安全TPP系统回顾性队列研究:在COVID-19大流行和2022年爆发期间A群链球菌感染的发病率和治疗状况
Christine Cunningham,Louis Fisher,Christopher Wood et al.
Christine Cunningham et al.
Objective: To investigate the effect of the covid-19 pandemic on the number of patients with group A streptococcal infections and related antibiotic prescriptions. ...
Regular use of fish oil supplements and course of cardiovascular diseases: prospective cohort study [0.03%]
鱼油补充剂的常规使用与心血管疾病的关系:前瞻性队列研究
Ge Chen,Zhengmin Min Qian,Junguo Zhang et al.
Ge Chen et al.
Objective: To examine the effects of fish oil supplements on the clinical course of cardiovascular disease, from a healthy state to atrial fibrillation, major adverse cardiovascular events, and subsequently death. ...
Development of a national maternity early warning score: centile based score development and Delphi informed escalation pathways [0.03%]
全国范围内的分娩早期预警评分系统的制定:分位数-based评分体系的建立和Delphi法确定的升级治疗路径
Stephen Gerry,Jonathan Bedford,Oliver C Redfern et al.
Stephen Gerry et al.
Objective: To derive a new maternity early warning score (MEWS) from prospectively collected data on maternity vital signs and to design clinical response pathways with a Delphi consensus exercise. ...
Participant characteristics and exclusion from phase 3/4 industry funded trials of chronic medical conditions: meta-analysis of individual participant level data [0.03%]
三期和四期行业资助的慢性疾病试验中纳入标准的特点及排除情况:参与人层面数据的元分析
Jennifer Lees,Jamie Crowther,Peter Hanlon et al.
Jennifer Lees et al.
Objectives: To assess whether age, sex, comorbidity count, and race and ethnic group are associated with the likelihood of trial participants not being enrolled in a trial for any reason (ie, screen failure). ...
To adjust or not to adjust: it is not the tests performed that count, but how they are reported and interpreted [0.03%]
调整或不调整:重要的是检验结果的报告和解释方式,而不是进行何种检验
Anne-Laure Boulesteix,Sabine Hoffmann
Anne-Laure Boulesteix
Identification of patients undergoing chronic kidney replacement therapy in primary and secondary care data: validation study based on OpenSAFELY and UK Renal Registry [0.03%]
基于OpenSAFELY和英国肾病登记的数据识别接受慢性肾脏替代治疗的患者:验证性研究
Shalini Santhakumaran,Louis Fisher,Bang Zheng et al.
Shalini Santhakumaran et al.
Objective: To validate primary and secondary care codes in electronic health records to identify people receiving chronic kidney replacement therapy based on gold standard registry data. ...
Neonatal hypoglycaemia [0.03%]
新生儿低血糖症
Jane E Harding,Jane M Alsweiler,Taygen E Edwards et al.
Jane E Harding et al.
Low blood concentrations of glucose (hypoglycaemia) soon after birth are common because of the delayed metabolic transition from maternal to endogenous neonatal sources of glucose. Because glucose is the main energy source for the brain, se...
Preterm prelabour rupture of membranes before 23 weeks' gestation: prospective observational study [0.03%]
早于妊娠23周的先兆流产破裂前羊膜综合征:前瞻性队列研究
Laura Goodfellow,Angharad Care,Ciara Curran et al.
Laura Goodfellow et al.
Objective: To describe perinatal and maternal outcomes of preterm prelabour rupture of membranes (PPROM) before 23 weeks' gestation in a national cohort. ...
Practical implications of the ADNEX risk prediction model for diagnosis of ovarian cancer [0.03%]
ADNEX风险预测模型的卵巢癌诊断临床意义分析
Saketh Guntupalli
Saketh Guntupalli
Characterization of accelerated approval status, trial endpoints and results, and recommendations in guidelines for oncology drug treatments from the National Comprehensive Cancer Network: cross sectional study [0.03%]
美国国立全面癌症网络关于肿瘤药物治疗的加速审批状况、试验终点和结果以及指导建议的特征:横断面研究
Maryam Mooghali,Aaron P Mitchell,Joshua J Skydel et al.
Maryam Mooghali et al.
Objectives: To evaluate National Comprehensive Cancer Network (NCCN) guideline recommendations for oncology drug treatments that have been granted accelerated approval, and to determine whether recommendations are updated...