Challenges in evaluating whole genome sequencing for newborn screening: series of systematic reviews and roadmap for evidence generation for policy advisers [0.03%]
新生儿筛查中全基因组测序的评价挑战：系统综述系列及政策顾问证据生成路线图
Karoline Freeman,Dylan Taylor,Jacqueline Dinnes et al.
Karoline Freeman et al.
Objective: To evaluate systematic review approaches to synthesising evidence for policy advisers who are considering whether to screen newborns for hundreds of rare diseases using whole genome sequencing. ...
Time to recognise the risks to patients after an eating disorder diagnosis [0.03%]
承认eating disorder诊断给患者带来的风险该是时候了
Ethan Nella,Jennifer Couturier
Ethan Nella
Adverse outcomes in patients with a diagnosis of an eating disorder: primary care cohort study with linked secondary care and mortality records [0.03%]
以诊疗记录和死亡记录为基础的队列研究中进食障碍患者不良预后的结果分析
Catharine Morgan,Matthew J Carr,Carolyn A Chew-Graham et al.
Catharine Morgan et al.
Objective: To examine the short and long term adverse physical and mental health outcomes, all cause mortality, and natural and unnatural deaths in individuals with a diagnosis of an eating disorder compared with a matche...
Nurse led telephonic palliative care versus specialty outpatient palliative care: pragmatic, randomised clinical trial [0.03%]
电话随访的护士主导姑息治疗与专科门诊姑息治疗的对比研究：实用随机临床试验
Corita R Grudzen,Mara Flannery,Kaitlyn Van Allen et al.
Corita R Grudzen et al.
Objective: To compare the effectiveness of nurse led telephonic palliative care versus specialty outpatient palliative care on quality of life, symptom burden, loneliness, and healthcare use, after attending the emergency...
Factors associated with: problems of using exploratory multivariable regression to identify causal risk factors [0.03%]
探索性多变量回归识别因果风险因素问题的影响因素
Dan Lewer,Thomas Brothers,Elizabeth O&#x;Nions et al.
Dan Lewer et al.
High risk human papillomavirus versus cytological screening over two rounds in Finnish screening programme for cervical cancer: population based cohort study [0.03%]
芬兰宫颈癌筛查项目中两次筛查的人乳头瘤病毒检查与细胞学检查的比较：基于人群的队列研究
Iiris Juulia Turunen,Ilkka Kalliala,Maiju Pankakoski et al.
Iiris Juulia Turunen et al.
Objective: To compare routine high risk human papillomavirus (hrHPV) screening with cytological screening in two screening rounds in a well established, routine screening programme for cervical cancer. ...
Inequalities in hormone replacement therapy prescribing in UK primary care: population based cohort study [0.03%]
基于人群的队列研究得出英国基层医疗中激素替代疗法处方不公的现象
Jennifer A Hirst,Wema Meranda Mtika,Carol Coupland et al.
Jennifer A Hirst et al.
Objective: To quantify prescribing of hormone replacement therapy (HRT) in women aged 40-60 years by type of HRT and length of use, and to determine sociodemographic factors associated with receiving a HRT prescription. ...
Penelope Hawe
Penelope Hawe
Trisha Greenhalgh
Trisha Greenhalgh
Case study is a widely used but poorly understood research method, conducted differently in different disciplines. This paper explores philosophical, theoretical and methodological issues in case study research and outlines how to conduct o...
Deep brain stimulation for Parkinson's disease: systematic review with meta-analysis and trial sequential analysis [0.03%]
帕金森病的深部脑刺激(DBS)系统评价及meta分析与序贯试验分析
Johanne Juul Petersen,Caroline Barkholt Kamp,Pascal Faltermeier et al.
Johanne Juul Petersen et al.
Objective: To assess the benefits and harms of deep brain stimulation for Parkinson's disease. Design: Systematic review with meta-anal...