PROTACs technology for treatment of Alzheimer's disease: Advances and perspectives [0.03%]
PROTAC技术治疗阿尔茨海默病的研究进展与前景展望
Hiroyuki Inuzuka,Jing Liu,Wenyi Wei et al.
Hiroyuki Inuzuka et al.
Neurodegenerative diseases (NDs) are characteristic with progression of neuron degeneration, resulting in dysfunction of cognition and mobility. Many neurodegenerative diseases are because of proteinopathies that results from unusual protei...
The regulation of neuronal autophagy and cell survival by MCL1 in Alzheimer's disease [0.03%]
Bclxl在阿尔茨海默病中通过调节神经元自噬和细胞存活作用于APP淀粉样病理过程及其表型后果
Abdol-Hossein Rezaeian,Wenyi Wei,Hiroyuki Inuzuka
Abdol-Hossein Rezaeian
Maintaining neuronal integrity and functions requires precise mechanisms controlling organelle and protein quality. Alzheimer's disease (AD) is characterized by functional defects in the clearance and recycling of intracellular components. ...