Nahed Ismail,Aditya Sharma,Lynn Soong et al.
Nahed Ismail et al.
Human monocytic ehrlichiosis, a tick transmitted infection, ranges in severity from apparently subclinical to a fatal toxic shock-like fatal disease. Models in immunocompetent mice range from an abortive infection to uniformly lethal depend...
Eight years' advances on Bourbon virus, a tick-born Thogotovirus of the Orthomyxovirus family [0.03%]
八种波旁病毒八年进展：一种正黏液病毒科托戈托病毒属的蜱传病毒
Siyuan Hao,Kang Ning,Çağla Aksu Küz et al.
Siyuan Hao et al.
Bourbon virus (BRBV) was first isolated from a blood sample collected from a male patient living in Bourbon county, Kansas, during the spring of 2014. The patient later died due to complications associated with multiorgan failure. Currently...
Mariola J Edelmann,Peter E Kima
Mariola J Edelmann
Extracellular vesicles (EVs) are membrane-enclosed packets released from cells that can transfer bioactive molecules from cell to cell without direct contact with the target cells. This transfer of molecules can activate consequential proce...
Yang Liu,Jianying Liu,Pei-Yong Shi
Yang Liu
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused global destruction since its emergence in late 2019. Over the past two years, the virus has continuously evolved in human host, leading to emergence of variants wit...
Xin-Zhuan Su,Jian Wu
Xin-Zhuan Su
Malaria is a deadly disease that affects the health of hundreds of millions of people annually. There are five Plasmodium parasite species that can naturally infect humans, including Plasmodium falciparum, Plasmodium vivax, Plasmodium malar...
Pattern Recognition Receptors in Innate Immunity to Obligate Intracellular Bacteria [0.03%]
模式识别受体在专性胞内细菌先天免疫中的作用
James R Fisher,Zachary D Chroust,Florence Onyoni et al.
James R Fisher et al.
Host pattern recognition receptors (PRRs) are crucial for sensing pathogenic microorganisms, launching innate responses, and shaping pathogen-specific adaptive immunity during infection. Rickettsia spp., Orientia tsutsugamushi, Anaplasma sp...
Venezuelan Equine Encephalitis Virus V3526 Vaccine RNA-Dependent RNA Polymerase Mutants Increase Vaccine Safety Through Restricted Tissue Tropism in a Murine Model [0.03%]
委内瑞拉马脑炎病毒V3526疫苗RNA依赖性RNA聚合酶突变体通过限制小鼠模型中的组织嗜性来增加疫苗安全性
Clint A Haines,Rafael K Campos,Sasha R Azar et al.
Clint A Haines et al.
Background: Venezuelan equine encephalitis virus (VEEV) is an arbovirus endemic to the Americas. There are no approved vaccines or antivirals. TC-83 and V3526 are the best-characterized vaccine candidates for VEEV. Both a...
Zika Virus Overview: Transmission, Origin, Pathogenesis, Animal Model and Diagnosis [0.03%]
寨卡病毒综述：传播、起源、发病机理、动物模型和诊断方法
Dallas Vue,Qiyi Tang
Dallas Vue
Zika virus (ZIKV) was first discovered in 1947 in Uganda. ZIKV did not entice much attention until Brazil hosted the 2016 Summer Olympics Game, where ZIKV attracted a global audience. ZIKV is a flavivirus that can be transmitted chiefly thr...