Drawing conclusions: blood culture yield across clinical scenarios in hematologic malignancy [0.03%]
血培养阳性率在血液系统恶性肿瘤中的临床影响因素分析
Jessica Seidelman,Patrick Tam,Julia Messina et al.
Jessica Seidelman et al.
Patients with hematologic malignancies are excluded from most blood culture stewardship algorithms. We evaluated blood culture collection patterns and bloodstream infection incidence across clinical scenarios in this population. Blood cultu...
Utilization of prospective, pharmacist-driven restriction criteria to improve appropriateness of empiric intravenous vancomycin use [0.03%]
应用前瞻性、药师驱动的限制标准以改善经验性静脉给药万古霉素的适宜性
Kinsey McClure Johannemann,Mark Jumper,Blain Thayer et al.
Kinsey McClure Johannemann et al.
Objective: This objective of this study is to evaluate the impact of a prospective, pharmacist-driven restriction protocol on the appropriateness of IV vancomycin use in a community hospital setting. ...
Is cefazolin an appropriate choice for preoperative prophylaxis in patients undergoing surgery for fracture-related infection [0.03%]
术前预防性使用头孢唑林治疗骨折相关感染患者是否合理？
Lauren Daddi,Marjorie Golden,David Frumberg et al.
Lauren Daddi et al.
Prophylaxis against fracture-related infections includes first generation cephalosporins. Open fractures may have soil contamination, increasing risk for infection with gram negative organisms. Broad spectrum antibiotics prevent infections ...
Antimicrobial stewardship in community pharmacies in Uyo, Akwa Ibom State: practices, barriers, and facilitators [0.03%]
尼日利亚乌约社区药房的抗菌药物管理：实践、障碍和促进因素
Mbuotidem Ime Akpan,Idongesit Linus Jackson,Unyime Israel Eshiet et al.
Mbuotidem Ime Akpan et al.
Objective: To evaluate the practices, barriers, and facilitators related to antimicrobial stewardship (AMS) in community pharmacies (CPs). Design: ...
Charting new territory: outpatient stewardship in immunocompromised patients (first of a two-part series) [0.03%]
开拓新领域：免疫 compromised患者门急诊治疗药物管理（一）
Alexander Shaffer,Rachel Bartash,Margaret E McCort et al.
Alexander Shaffer et al.
Antimicrobial stewardship (AS) among immunocompromised (IC) patients is a growing field. Since most antibiotic use occurs in the outpatient setting, antimicrobial use among IC outpatients represents an opportune area for stewardship. This t...
Risk factors associated with extended spectrum beta lactamase Klebsiella pneum oniae outbreak in a neonatal intensive care unit [0.03%]
新生儿重症监护病房中扩展谱贝塔内酰胺酶克雷伯菌暴发的危险因素分析
Areej Yousef Al Ali,Gautam Hebbar,Dalal Al-Ghanim et al.
Areej Yousef Al Ali et al.
Objective: (1) identify risk factors for extended-spectrum beta-lactamase Klebsiella pneumoniae (ESBL-KP) acquisition in the neonatal intensive care unit (NICU) and (2) evaluate the clinical impact of ESBL-KP acquisition ...
A multidrug-resistant organism tracking and alert system is associated with lower MRSA and CP-CRE infection rates at Veterans Affairs Medical Centers [0.03%]
美国退伍军人事务部医学中心的耐多药菌监测和预警系统与降低MRSA和CP-CRE感染率相关
Amanda Vivo,Cara Ray,Tarek El Ali et al.
Amanda Vivo et al.
This study investigates Veterans Affairs Bug Alert (VABA) usage on methicillin-resistant Staphylococcus aureus (MRSA) and carbapenemase-producing carbapenem-resistant Enterobacterales (CP-CRE) infection rates in VA facilities. Significant a...
Hepatotoxicity in hematologic malignancy and hematopoietic stem cell transplant patients receiving posaconazole or isavuconazole prophylaxis: a single-center cohort study [0.03%]
一项单中心队列研究：在接受泊沙康唑或艾沙康唑预防性治疗的血液系统恶性肿瘤和造血干细胞移植患者中的肝毒性反应
Samantha Steele,Courtney Nichols,Kelci Coe et al.
Samantha Steele et al.
Objective: To assess and compare the incidence, timing, and severity of hepatotoxicity associated with prophylactic isavuconazole and posaconazole in patients with hematologic malignancies or a history of hematopoietic st...
Where antibiotic time-outs work: department- and ward-stratified effects of a pharmacist-led anti-MRSA time-out [0.03%]
抗生素暂停的实施效果：基于药剂师领导的抗MRSA时间调查的部门和病房分层效应分析
Risako Yamamoto,Yasuaki Tagashira,Do Dang An et al.
Risako Yamamoto et al.
Objective: To assess the impact of a pharmacist-led anti-methicillin-resistant Staphylococcus aureus (MRSA) agents' time-out and identify clinical areas most likely to benefit. ...
Impact of intravenous push antibiotics on sepsis management at a Veterans Affairs medical center emergency department [0.03%]
静脉注射抗生素在退伍军人事务医学中心急诊科管理脓毒症中的影响
Mercy Hoang-Nguyen,Kang Lim,Catherine Vo et al.
Mercy Hoang-Nguyen et al.
Objective: To detail the impact of transitioning from intravenous piggyback (IVPB) to intravenous push (IVP) antibiotics on median time from sepsis identification to antibiotic administration (minutes), proportion of sept...