Cancer risk after preeclampsia: a cohort study in two Nordic populations [0.03%]
子痫前期后的癌症风险：两项北欧人群队列研究
Golbarg Vesterlund,Xinhe Mao,Mika Gissler et al.
Golbarg Vesterlund et al.
Background: Limited evidence suggests that preeclampsia (PE) is associated with reduced cancer risk later in life. We aimed to investigate this using large registry-based cohorts. We hypothesised that enhanced immune acti...
Silvia Riva
Silvia Riva
Financial toxicity is increasingly acknowledged as a growing challenge in oncology. While it has been extensively researched internationally, the UK lags behind, hindering the adoption of patient-centred approaches. This contribution explor...
Cytoskeleton imaging of colorectal and lung cancer spheroids using light sheet microscopy [0.03%]
利用光片荧光显微镜对结直肠癌和肺癌类器官进行细胞骨架成像
Sonia Prado-López,Massih Foroughipour,Klaus Becker et al.
Sonia Prado-López et al.
Background: Three dimensional tumoral models are essential to study cancer biology as they better mimic the complexity of the tumoral masses in vivo. However, to study cancer 3D models' dynamics new technological approach...
Whole genome sequencing and single-cell transcriptomics identify KMT2D inactivation as a potential new driver for pituitary tumors: a case report [0.03%]
全基因组测序和单细胞转录组揭示KMT2D失活可能是垂体肿瘤新的驱动因素：病例报告
Maxime Brunner,Jenny Meylan-Merlini,Maude Muriset et al.
Maxime Brunner et al.
The pituitary gland is a main component of the endocrine system and a master controller of hormone production and secretion. Unlike neoplastic formation in other organs, Pituitary Neuroendocrine Tumors (PitNETs) are frequent in the populati...
The influence of clinical risk factors on the classification of human cancer-associated fibroblasts in PDAC and pancreatitis patients [0.03%]
临床风险因素对胰腺癌和胰腺炎患者癌症相关成纤维细胞分类的影响
Viktoria Boeker,Lena Wilke,Ana Mansourkiaei et al.
Viktoria Boeker et al.
Cancer-associated fibroblasts (CAFs) constitute an important cell population in the microenvironment of pancreatic cancer. They can arise from disease-associated fibroblasts (DAFs) to support or restrain tumor growth. How many CAF subtypes ...
Cancer prognosis and treatment results in patients with PTEN Hamartoma Tumour Syndrome (PHTS)-a European cohort study [0.03%]
PTEN错构瘤肿瘤综合症（PHTS）患者的癌症预后和治疗结果-一项欧洲队列研究
Linda A J Hendricks,Katja C J Verbeek,Janneke H M Schuurs-Hoeijmakers et al.
Linda A J Hendricks et al.
Background: PTEN hamartoma tumour syndrome (PHTS) patients have a high hereditary risk of cancer, especially breast (BC), endometrial (EC), and thyroid cancer (TC). However, the prognosis of PHTS-related cancers is unknow...
Real-world treatment outcomes and clinicopathologic and molecular determinants of response to first-line lenvatinib in patients with advanced follicular cell-derived thyroid cancer [0.03%]
仑伐替尼一线治疗分化型甲状腺癌的临床疗效及影响因素分析
Kara M Ruicci,Yangqing Deng,Tian Xiao et al.
Kara M Ruicci et al.
Background: There is a paucity of real-world data regarding lenvatinib for locally-recurrent, metastatic and RAI-refractory thyroid cancer. Here we examined the efficacy of first-line lenvatinib in a genomically-character...
Adèle Hegoburu,Mohammad Amer,Frank Frizelle et al.
Adèle Hegoburu et al.
Recent advances in immuno-oncology research have revolutionised our understanding of the interplay between immune cells and the tumour microenvironment (TME), profoundly impacting patient responses to therapy. The TME, comprising tumour cel...
Identification of recurrences in women diagnosed with early invasive breast cancer using routinely collected data in England [0.03%]
利用英国的常规数据识别早期侵袭性乳腺癌患者的复发情况
Jake Probert,David Dodwell,John Broggio et al.
Jake Probert et al.
Background: Breast cancer is the commonest cancer in the UK, with around 55,000 women diagnosed annually. Information is routinely available on breast cancer mortality but not on recurrence. ...