Minggui Pan,Meng M Tong,Jack Stover et al.
Minggui Pan et al.
Purpose: To examine potential overall survival (OS) differences between males and females with advanced gastric (GAC), gastroesophageal junction (GEJAC) and esophageal (EAC) adenocarcinoma. ...
A retrospective study of the impact of comorbidity, polypharmacy and demographic factors on patient inclusion and healthcare delivery in phase I oncology trials [0.03%]
一项回顾性研究：合并症、用药种类和人口统计学因素对I期肿瘤临床试验受试者入选及医疗保健的影响
Hoda Nemat,Martin Orr,Lucy Barrow et al.
Hoda Nemat et al.
Background: Phase I trials include patients with metastatic cancer and complex health conditions. Understanding baseline comorbidity and demographic features is critical to improving trial design. ...
Breast cancer survival in a rural setting in the Busoga Region of Uganda [0.03%]
乌干达Busoga地区的农村环境中乳腺癌的生存率
Rasmus Kallestrup,Katinka Bolette Lorentzen,John Mwayi et al.
Rasmus Kallestrup et al.
Background: Breast cancer (BC) poses a significant health challenge globally. While high-income countries benefit from robust healthcare systems, sub-Saharan Africa (SSA) faces elevated BC mortality rates. Despite extensi...
Hidden costs and unmet supportive care needs among individuals with experience of breast cancer and their carers in the United Kingdom [0.03%]
英国乳腺癌患者及其家属的支持性护理需求未获满足的隐性成本探究
Szeyi Ng,Lucy S Kilburn,Hilary Stobart et al.
Szeyi Ng et al.
Background: The impact of cancer transcends physical health, affecting mental wellbeing, financial stability, and ability to perform daily tasks, influencing not only patients but also the broader community. ...
Long-term outcomes of consecutive patients of oropharyngeal cancer treated with radical radiotherapy [0.03%]
接受根治性放射治疗的连续型口咽癌患者长期预后研究
Ashwini Budrukkar,Sheetal R Kashid,Monali Swain et al.
Ashwini Budrukkar et al.
Objectives: Given the wide variation in the incidence of Human Papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC), we aimed to evaluate the prevalence of HPV and assess treatment outcomes in pat...
Monoclonal antibody for phosphorylated TRIO Y2681 that helps predict prognosis of post-operative colorectal cancer patients [0.03%]
用于预测结直肠癌术后患者预后的TRIO Y2681磷酸化单克隆抗体
Taro Aoyama,Fumihiko Kakizaki,Hiroyuki Miyoshi et al.
Taro Aoyama et al.
Background: We previously reported that TRIO pY2681, a novel prognostic biomarker for CRC, can be detected by polyclonal antibodies (pAb). We have now developed a novel monoclonal antibody (mAb) that recognizes TRIO pY268...
Circulating tumor DNA monitoring detects minimal residual disease and predicts outcomes in patients with esophageal adenocarcinoma or squamous cell carcinoma after esophagectomy [0.03%]
食管切除术后循环肿瘤DNA监测可检测食管腺癌和鳞状细胞癌患者的残留病灶并预测预后
Qingjiang Hu,Yasue Kimura,Shinichiro Ikeda et al.
Qingjiang Hu et al.
Background: Circulating tumor DNA (ctDNA) monitoring shows promise for detecting minimal residual disease (MRD) and predicting prognosis in various cancers, but its role in esophageal cancer (EC) post-esophagectomy is unc...
Interplay between AHR genotypes, lifestyle factors and adjuvant breast cancer treatments significantly impacts clinical outcome in a population-based cohort [0.03%]
基于人群的队列研究中AHRR基因型、生活方式因素和辅助性乳腺癌治疗与临床结局之间的相互作用具有显著的影响
Annelie Augustinsson,Christopher Godina,Linn Nilsson et al.
Annelie Augustinsson et al.
Background: The purpose was to evaluate the prognostic impact of aryl hydrocarbon receptor (AHR) genotypes in relation to lifestyle and adjuvant treatments in breast cancer. ...
Patient derived cancer-associated fibroblasts from non-small cell lung cancer undergo phenotypic drift in culture [0.03%]
非小细胞肺癌患者来源的癌相关成纤维细胞体外培养后表型漂变
Layla Mathieson,Phoebe Jones,Lilian Koppensteiner et al.
Layla Mathieson et al.
Background: Cancer-associated fibroblasts (CAFs) are the predominant cell type in the stroma of many solid organ malignancies, including non-small cell lung cancer (NSCLC). They exhibit considerable phenotypic and functio...
IL-6R expression is an independent prognostic factor in high-grade serous ovarian cancer [0.03%]
高浆液性卵巢癌中IL-6R的表达是一个独立的预后因素
Alexis M Maagdenberg,Annegé Vledder,Sterre T Paijens et al.
Alexis M Maagdenberg et al.
Background: HGSOC is the leading cause of death among all gynaecological malignancies. We recently identified that genomically unstable cancers that display high levels of chromosomal instability, including HGSOC, rely on...