The role of virtual consultations in cancer genetics: challenges and opportunities introduced by the COVID-19 pandemic [0.03%]
新冠肺炎疫情下肿瘤遗传学虚拟咨询的作用：挑战与机遇
Melody G Redman,Vernie Aguda,Rhys Dore et al.
Melody G Redman et al.
The COVID-19 pandemic changed the delivery of healthcare within the United Kingdom. A virtual model of care, utilising telephone and video consultations, was rapidly imposed upon cancer genetics teams. This large-scale change in service del...
ASSIGN score and cancer risk in the Scottish Heart Health Extended Cohort (SHHEC) study [0.03%]
苏格兰心脏健康扩展队列（SHHEC）研究中的 ASSIGN 得分和癌症风险
Catherine A Fitton,Mark Woodward,Jill Jf Belch
Catherine A Fitton
Background: The aim of this work was to determine whether the ASSIGN cardiovascular disease (CVD) score, a 10-year CVD risk score used in primary care in Scotland, could additionally detect cancer risk. ...
Determining the efficacy of ExThera Seraph100 blood filtration in patients diagnosed with pancreatic cancer through the liquid biopsy [0.03%]
通过液体活检确定ExThera Seraph100血液滤过在胰腺癌患者中的疗效
Stephanie N Shishido,Divya Suresh,George Courcoubetis et al.
Stephanie N Shishido et al.
Background: Cancer becomes lethal as it spreads from the primary site to the rest of the body. Circulating tumor cells (CTCs) are biomarkers of disease progression and have been associated with decreased overall survival....
Using the Candidacy Framework to understand individual, interpersonal, and system level factors driving inequities in women with breast cancer: a cross-sectional study [0.03%]
利用候选人框架理解个体、人际和系统层面的因素，这些因素驱动了乳腺癌女性患者之间的不平等：一项横断面研究
Mar Estupiñán Fdez de Mesa,Afrodita Marcu,Emma Ream et al.
Mar Estupiñán Fdez de Mesa et al.
Background: Persistent inequities in breast cancer outcomes exist. Understanding women's experiences along the care pathway is the first step to finding solutions to tackle these inequities. ...
Progression of chronic liver disease to hepatocellular carcinoma: implications for surveillance and management [0.03%]
慢性肝病进展为肝细胞癌：筛查和管理的启示
Philip J Johnson,Anton Kalyuzhnyy,Ellen Boswell et al.
Philip J Johnson et al.
Background: Current opinion holds that hepatocellular carcinoma (HCC) arises as a stepwise progression from chronic liver disease (CLD) to cirrhosis and then to HCC. However, some HCCs may develop in a non-cirrhotic liver...
Survival benefit of cytoreductive surgery in patients with primary stage IV endometrial cancer: a systematic review & meta-analysis [0.03%]
子宫内膜癌全面分期手术能带来生存获益吗？系统评价和meta分析
Eveline Ngoc Bao Pham,Nanda Horeweg,Jacolien van der Marel et al.
Eveline Ngoc Bao Pham et al.
Background: This systematic review and meta-analysis aimed to investigate the survival outcomes following cytoreductive surgery (CRS) in patients with primary stage IV endometrial cancer (EC). ...
Breast cancer risk assessment based on susceptibility genes and polygenic risk score in Vietnamese women [0.03%]
越南女性乳腺癌风险评估基于易感基因和多基因风险评分
Dao Nguyen Vinh,Thanh Thi Ngoc Nguyen,Tuan-Anh Nguyen Tran et al.
Dao Nguyen Vinh et al.
Background: Breast screening recommendation based on individual risk assessment is emerging as an alternative approach to improve compliance and efficiency to detect breast cancer (BC) early. In Vietnam, prior knowledge t...
Lung cancer in never smokers (LCINS): development of a UK national research strategy [0.03%]
从不吸烟者的肺癌（LCINS）：英国全国研究策略的制定
Sam Khan,Nathaniel Hatton,Daniel Tough et al.
Sam Khan et al.
Introduction: Lung cancer in never smokers (LCINS) accounts for 15% of lung cancers diagnosed in the UK, making it the 8th most common cancer. There are few robust studies specific to the LCINS population making data surr...
Circulating extracellular vesicles containing S100A9 reflect histopathology, immunophenotype and therapeutic responses of liver metastasis in colorectal cancer patients [0.03%]
含有S100A9的循环细胞外囊泡反映结直肠癌肝转移患者的病理组织学、免疫表型和治疗反应
Migmar Tsamchoe,Anthoula Lazaris,Diane Kim et al.
Migmar Tsamchoe et al.
Background: Metastasis is the principal cause of cancer treatment failure and an area of dire diagnostic needs. Colorectal cancer metastases to the liver (CRCLMs) are predominantly classified into desmoplastic and replace...
Direct administration of human leucocyte antigen (dHLA) molecules into tumour sites: proposal for a new immunotherapy for cancer [0.03%]
直接向肿瘤部位管理人类白细胞抗原分子：癌症免疫治疗的新建议
Apostolos P Georgopoulos,Lisa M James
Apostolos P Georgopoulos
Natural elimination of cancer cells is mediated by human leucocyte antigen (HLA) Class I and II molecules [1] that bind to tumour protein fragments, move to the tumour cell surface and engage CD8+ lymphocytes for killing the tumour cell (HL...