Prevalence of the human papillomavirus (HPV) types among cervical dysplasia women attending a gynaecological clinic in Sweden [0.03%]
瑞典妇科诊所宫颈上皮内瘤变女性的人乳头状瘤病毒(HPV)型别分布状况研究
Fabricio Romero García,Johanna Norenhag,Gabriella Edfeldt et al.
Fabricio Romero García et al.
Background: Human papillomavirus (HPV) is the main cause of cervical cancer. HPV-vaccines have led to a significant decrease in HPV-infections and related cancer cases. The estimation of the current HPV-prevalence and dis...
Lorlatinib in the second line and beyond for ALK positive lung cancer: real-world data from resource-constrained settings [0.03%]
二联或后续 lorlatinib 治疗ALK阳性肺癌：资源有限环境下的真实世界数据
Amit Kumar,Akhil Kapoor,Vanita Noronha et al.
Amit Kumar et al.
Background: ALK-positive lung cancers are known to have favorable responses with oral tyrosine kinase inhibitors. Lorlatinib is an approved treatment option post first and second-line ALK inhibitors and is now also in fir...
The amino-acid stress sensing eIF2α kinase GCN2 is a survival biomarker for malignant mesothelioma [0.03%]
氨基酸压力感应eif2α激酶gcn2可作为恶性间皮瘤的生存生物标志物
Lyssa T Gold,Susan E Bray,Neil M Kernohan et al.
Lyssa T Gold et al.
Background: Malignant mesothelioma is a tumour that is strongly associated with a history of asbestos exposure, and which derives from mesothelial cells that line the serous cavities of the body. The tumour most commonly ...
The impact of VEGF signalling pathway inhibitors and/or immune checkpoint inhibitors on kidney function over time: a single centre retrospective analysis [0.03%]
VEGF信号通路抑制剂和/或免疫检查点抑制剂对肾功能的纵向影响：一项单中心回顾性分析
Benjamin M P Elyan,Michael K Sullivan,James Hedley et al.
Benjamin M P Elyan et al.
Background: Drugs targeting angiogenesis and immunotherapy have transformed outcomes in renal cancer but may contribute to progressive kidney disease. Met...
Temporal evolution and inter-patient heterogeneity in primary and recurrent head and neck squamous cell carcinoma [0.03%]
原发和复发头颈鳞癌的时序演变及患者间异质性研究
Luisa Bresadola,David Weber,Christoph Ritzel et al.
Luisa Bresadola et al.
Background: Head and neck squamous cell carcinomas (HNSCCs) are heterogeneous in terms of origin and aetiology. In addition, there is uncertainty about the genetic evolution from initial diagnosis to recurrence after prim...
Response to Penetrance estimates of hereditary cancers in a population setting using UK Biobank data [0.03%]
基于UK Biobank数据估计人口层面遗传性癌症的外显率
Leigh Jackson,Michael N Weedon,Harry D Green et al.
Leigh Jackson et al.
Seamus O&#x;Reilly,Karie Dennehy,Dearbhaile C Collins
Seamus O&#x;Reilly
Radiomics and outcome prediction to antiangiogenic treatment in advanced gastroenteropancreatic neuroendocrine tumours: findings from the phase II TALENT trial [0.03%]
基于影像组学和预后的抗血管生成治疗预测在晚期胃肠胰神经内分泌肿瘤中的应用：TALENT二期临床试验结果
Marta Ligero,Jorge Hernando,Eric Delgado et al.
Marta Ligero et al.
Background: More accurate predictive biomarkers in patients with gastroenteropancreatic neuroendocrine tumours (GEP-NETs) are needed. This study aims to investigate radiomics-based tumour phenotypes as a surrogate biomark...
Bavani Gunasegaran,Caroline L Ashley,Felix Marsh-Wakefield et al.
Bavani Gunasegaran et al.
Background: Glioblastoma (GB) is a lethal and aggressive brain tumour. While molecular characteristics of GB is studied extensively, the aetiology of GB remains uncertain. The interest in exploring viruses as a potential ...
Joan H Schiller
Joan H Schiller
A warming planet will have devasting effects on human health - including the care, diagnosis, prevention, and treatment of cancer patients. As oncology health care professionals, we have a moral and professional obligation to educate our pe...