Racial and socioeconomic disparities in survival improvement of eight cancers [0.03%]
八种癌症生存率的种族和经济社会差异性
Vikram Shaw,Baoyi Zhang,Mabel Tang et al.
Vikram Shaw et al.
Background: Many studies have characterized racial differences in cancer outcomes, demonstrating that black and Hispanic patients have lower cancer-specific survival compared to white patients. However, to our knowledge, ...
Aromatase inhibitors and fracture prevention - do 2017 guidelines work in real world? [0.03%]
aromatase抑制剂与骨折预防-2017年指南在实际应用中有效吗？
Anem Mirza,Zeyar Win Naing,Parisa Khonsari et al.
Anem Mirza et al.
Objectives: Aromatase inhibitor induced bone loss (AIBL) is a recognised adverse event with resultant increase in fracture risk. We aimed to determine the real-world impact of the 2017 consensus guidelines on AIBL and see...
Predictive model of castration resistance in advanced prostate cancer by machine learning using genetic and clinical data: KYUCOG-1401-A study [0.03%]
基于遗传和临床数据的机器学习预测晚期前列腺癌去势抵抗的模型：KYUCOG-1401-A研究
Masaki Shiota,Shota Nemoto,Ryo Ikegami et al.
Masaki Shiota et al.
Background: The predictive power of the treatment efficacy and prognosis in primary androgen deprivation therapy (ADT) for advanced prostate cancer is not satisfactory. The objective of this study was to integrate genetic...
Accuracy of ultrasound, magnetic resonance imaging and intraoperative frozen section in the diagnosis of ovarian tumours: data from a London tertiary centre [0.03%]
超声、磁共振和术中冷冻切片对卵巢肿瘤诊断价值的比较(伦敦一家三级医疗中心的数据)
Sian Mitchell,Joseph Gleeson,Mansi Tiwari et al.
Sian Mitchell et al.
Background: Ovarian cancer has the worst prognosis among all gynaecological cancers. The pre-operative and intraoperative diagnosis of ovarian tumours is imperative to ensure the right operation is performed and to improv...
Real-world effectiveness of CDK 4/6 inhibitors in estrogen-positive metastatic breast cancer [0.03%]
CDK4/6抑制剂治疗雌激素受体阳性转移性乳腺癌的现实世界有效性研究
Mathilde Louise Gehrchen,Tobias Berg,Rasmus Garly et al.
Mathilde Louise Gehrchen et al.
Background: Initial treatment for advanced ER-positive/HER2-negative breast cancer involves a CDK 4/6 inhibitor (CDK 4/6i). Recent overall survival (OS) analyses led the Danish Medical Council to exclude palbociclib as pr...
Predictive and prognostic value of excision repair cross-complementing group 1 in patients with advanced gastric cancer [0.03%]
ERCC1对晚期胃癌患者的预测和预后价值
Yasuhide Yamada,Kengo Nagashima,Mizutomo Azuma et al.
Yasuhide Yamada et al.
Background: To define the optimal chemotherapy regimen for each patient we therefore used tissue from patients to identify molecular prognostic or predictive biomarkers. ...
Single cell atlas of kidney cancer endothelial cells reveals distinct expression profiles and phenotypes [0.03%]
肾脏癌症内皮细胞单细胞图谱揭示了不同的表达模式和表型特征
Yuexin Xu,Chris P Miller,Jun Xue et al.
Yuexin Xu et al.
Background: Tumor endothelial cells (TECs) represent the primary interface between the tumor microenvironment and circulating immune cells, however their phenotypes are incompletely understood in highly vascularized clear...
New insights into macrophage polarization and its prognostic role in patients with colorectal cancer liver metastasis [0.03%]
巨噬细胞极化在结直肠癌肝转移患者中的作用及预后价值的新认识
Isha Khanduri,Harufumi Maki,Anuj Verma et al.
Isha Khanduri et al.
Background: As liver metastasis is the most common cause of mortality in patients with colorectal cancer, studying colorectal cancer liver metastasis (CLM) microenvironment is essential for improved understanding of tumor...
System transferability of Raman-based oesophageal tissue classification using modern machine learning to support multi-centre clinical diagnostics [0.03%]
基于拉曼的机器学习食管组织分类的系统迁移能力以支持多中心临床诊断
Nathan Blake,Riana Gaifulina,Martin Isabelle et al.
Nathan Blake et al.
Background: The clinical potential of Raman spectroscopy is well established but has yet to become established in routine oncology workflows. One barrier slowing clinical adoption is a lack of evidence demonstrating that ...
Expression of transglutaminase-2 (TGM2) in the prognosis of female invasive breast cancer [0.03%]
TGTM2在女性浸润性乳腺癌预后中的表达
Fiona M Blows,H Raza Ali,Wei Cope et al.
Fiona M Blows et al.
Background: Transglutaminase 2 (TGM2) is a protein expressed in several isoforms in both intra- and extra-cellular tissue compartments. It has multiple functions that are important in cancer biology and several small stud...