[Half a century of gene expression analysis : The path to modern spatial transcriptomics in autopsy tissue] [0.03%]
半个世纪的基因表达分析：从现代尸检组织空间转录组学的角度展望
Torben Redmer,Josefine Radke,Helena Radbruch
Torben Redmer
Over the past five decades, gene expression analysis has evolved from classical methods such as Northern blot and in situ hybridization to high-resolution sequencing techniques. For the first time, modern technologies, such as spatial trans...
Sarah Theurer,Sabrina Borchert,Elisabeth Bednaric et al.
Sarah Theurer et al.
A 21-year-old female presented with a 1 cm red, polypoid cutaneous tumor near the axilla that was surgically excised. Histomorphology revealed a subepithelial tumor with features suggestive of a granular cell tumor; however, immunohistochem...
[Proteomics and glycomics in pathology : Potential of autopsy and FFPE tissue for diagnostics and research] [0.03%]
[病理学中的蛋白质组和糖组：尸检和FFPE组织的诊断和研究潜力]
Falk Buettner,Rainer Claus
Falk Buettner
The repertoire of disease-associated, formalin-fixed, paraffin-embedded (FFPE) samples collected and archived over decades is vast. When combined with frequently available and detailed clinical information on patients, disease progression, ...
L Rentschler,F Farfán López
L Rentschler
Background: Despite major advances in ante-mortem diagnostics, clinicopathological autopsy remains a central instrument for determination of the cause of death, clinical quality assurance, and medical research. At the sam...
[SARIFA: Literature review and expert opinion on the new morphological biomarker] [0.03%]
【SARIFA：形态学新生物标志物的文献综述与专家意见】
Patrick Adam,Bruno Märkl
Patrick Adam
Background: Stroma areactive invasion front area (SARIFA) was recently defined and introduced as a histomorphological, prognostic biomarker for various carcinomas. ...
Thomas Mentzel
Thomas Mentzel
Immunohistochemistry has an essential role in the diagnosis and differential diagnosis of benign and malignant melanocytic lesions, and underlying molecular changes are reflected by several newly characterized antibodies. Given the limited ...
Annette M Müller
Annette M Müller
Felix Elsner,Lena-Maria Löwer-Kiem,Florian Fuchs et al.
Felix Elsner et al.
Immune checkpoint inhibitors combined with conventional chemotherapy have led to significantly improved outcomes in the neoadjuvant and perioperative treatment of non-small cell lung cancer (NSCLC), establishing chemoimmunotherapy as the st...
[Neuropathologist and brain researcher Lieselotte Gerhard (1925-2010)] [0.03%]
neuropath学家和脑研究者Lieselotte Gerhard(1925-2010)
Ann Britt Siemer,Holger Steinberg
Ann Britt Siemer
Background: To date, little research has been conducted on the lives and contributions of the first women appointed as professors of medicine in Germany. Lieselotte Gerhard was one of these first female professors in the ...
[Brain dissection in general pathology : Practical recommendations from a neuropathological perspective] [0.03%]
[从神经病理学角度对一般病理学中脑切片实践建议]
Friederike Liesche-Starnecker,Zuzanna Mielewczyk,Przemyslaw Grochowski et al.
Friederike Liesche-Starnecker et al.
Background: Since neuropathology departments in Germany are mainly located only at university hospitals, brain sections are frequently performed by general pathologists. This article provides practical recommendations for...