Jörg Beimler
Jörg Beimler
[New treatment option for locally advanced dMMR/MSIhigh rectal cancer] [0.03%]
局部晚期dMMR/MSI高位直肠癌的新治疗选择
Stefan Kasper-Virchow,Sirka Nitschmann
Stefan Kasper-Virchow
[Influence of clonal hematopoiesis on non-hematological diseases and aging processes] [0.03%]
克隆性造血对非血液系统疾病和衰老进程的影响
Michael A Rieger
Michael A Rieger
The occurrence of clonal hematopoiesis, caused by acquired somatic mutations of leukemia-associated genes in blood stem cells is very common in the population and increases with age. Besides an increased risk of developing myeloid neoplasms...
[Sodium reduction in patients with heart failure : Study of Dietary Intervention Under 100 mmol in Heart Failure (SODIUM-HF)] [0.03%]
心力衰竭患者降钠治疗的疗效：心力衰竭低于100毫摩尔膳食干预研究(SODIUM-HF)
S Grundmann,D Westermann,S Nitschmann
S Grundmann
K Herfurth,J Ruhe,K Kentouche et al.
K Herfurth et al.
Thrombotic thrombocytopenic purpura (TTP) remains a serious illness with potentially life-threatening complications. The following case of a TTP patient describes a serious relapse with exacerbation in spite of adequately initiated therapy ...
Fabian Frost,Markus M Lerch
Fabian Frost
Josef Heusinger,Paul Czech,Heidi Hengstler et al.
Josef Heusinger et al.
Paraneoplastic leukocytosis in solid tumors is associated with poor prognosis. While mild leukocytosis is common, paraneoplastic hyperleukocytosis is extremely rare. The case of a 73-year-old male diagnosed with an adenocarcinoma of the lun...
Raphael Teipel,Malte von Bonin,Friedrich Stölzel et al.
Raphael Teipel et al.
The detection of clonal hematopoiesis (CH) in patients with hematologic neoplasms who are undergoing a cellular therapy is common. The most frequently used cellular therapy procedures include autologous and allogeneic hematopoietic stem cel...
Christopher Maximilian Arends,Frederik Damm
Christopher Maximilian Arends
Background: Clonal hematopoiesis (CH) is a premalignant state of the hematopoietic system that frequently occurs in old age and is associated with an elevated cardiovascular risk and higher overall mortality. ...
[Management of chronic heart failure: state of the art according to the 2021 guideline] [0.03%]
慢性心力衰竭的管理：2021指南解读
Kristian Hellenkamp,Miroslava Valentova,Stephan von Haehling
Kristian Hellenkamp
Treatment of heart failure with reduced ejection fraction (HFrEF) requires four drug classes that should be initiated simultaneously and up-titrated rapidly. All four have received class I recommendations. Sacubitril/valsartan can be consid...