Rika Draenert,Johannes Bogner,Alexandra Weber
Rika Draenert
Intravenous antibiotic therapy has traditionally been considered the standard treatment for severe infections. However, recent research shows that early switching to oral antibiotics is often equivalent or even superior. This is made possib...
Sandra Mangiapane,Thomas Czihal,Emil Hu et al.
Sandra Mangiapane et al.
Background: Ambulatory healthcare in Germany is under pressure due to the increasing need for care, medical progress and a shortage of specialist personnel. Making general practitioners mandatory gatekeepers is on the pol...
[Outpatient parenteral antimicrobial therapy: challenges and opportunities] [0.03%]
门诊抗菌素静脉给药治疗：挑战与机遇
Johanna Erber,Lukas Tometten,Clara Lehmann
Johanna Erber
Outpatient parenteral antimicrobial therapy (OPAT) enables the intravenous administration of anti-infective agents outside the hospital, within the patient's home environment, and can thereby shorten or even avoid inpatient stays. Internati...
Martin Griesshammer
Martin Griesshammer
Myelofibrosis (MF) is a rare clonal disease of the haematopoietic stem cell characterised by pathological activation of the JAK/STAT signalling pathway. The disease typically manifests clinically as anaemia, splenomegaly and constitutional ...
Caroline Evers,Jörg Distler,Oliver Distler
Caroline Evers
Systemic sclerosis (SSc) is a rare autoimmune connective tissue disease within the spectrum of rheumatologic disorders. It is characterized by a combination of vasculopathy and inflammatory fibrosis affecting the skin and various internal o...
Kai M Schmidt-Ott
Kai M Schmidt-Ott
[When AIHA does not explain everything: parvovirus B19 infection and pancytopenia as a differential diagnostic challenge] [0.03%]
当AIHA不能解释一切时：Parvovirus B19感染和全血细胞减少作为鉴别诊断的挑战
W Harms,R Akdas,C Jacob et al.
W Harms et al.
A 48-year-old female patient with known autoimmune hemolytic anemia (AIHA) presented with severe anemia and pancytopenia. Despite typical hemolysis parameters and a positive direct antiglobulin test confirming the presence of warm autoantib...
[The role of disease-specific registries in the field of rare diseases: opportunities, benefits and pitfalls] [0.03%]
罕见病领域疾病特异性登记处的作用：机遇、益处和陷阱
J Vasseur,V Britz,J König et al.
J Vasseur et al.
Background: Individuals affected by rare diseases often describe the path to diagnosis as an odyssey, and even after diagnosis, there is a need for improvement in the subsequent care. Registries represent one of many buil...