Network temperature as a metric of stability in depression symptoms across adolescence [0.03%]
青春期抑郁症症状稳定的网络温度指标
Poppy Z Grimes,Aja L Murray,Keith Smith et al.
Poppy Z Grimes et al.
Depression is characterized by diverse symptom combinations that can be represented as dynamic networks. While previous research has focused on central symptoms for targeted interventions, less attention has been given to whole-network prop...
Identification of risk variants and cross-disorder pleiotropy through multi-ancestry genome-wide analysis of alcohol use disorder [0.03%]
多祖先酒精使用障碍全基因组分析鉴定风险变异和跨疾病多重遗传性
Romain Icick,Alexey Shadrin,Børge Holen et al.
Romain Icick et al.
Alcohol use disorder (AUD) is highly heritable and burdensome worldwide. Genome-wide association studies (GWASs) can provide new evidence regarding the aetiology of AUD. We report a multi-ancestry GWAS focusing on a narrow AUD phenotype, us...
Hailey A Trier,Jill X O&#x;Reilly,Lisa Spiering et al.
Hailey A Trier et al.
A common behavior in natural environments is foraging for rewards. However, this is often in the presence of predators. Therefore, one of the most fundamental decisions for humans, as for other animals, is how to apportion time between rewa...
Sandra Baez,Laura Castro-Aldrete,Gabrielle B Britton et al.
Sandra Baez et al.
Gender inequality substantially impacts society, disproportionately disadvantaging women, especially in the Global South. This inequality correlates with brain health outcomes for women, including a higher risk of cognitive decline and deme...
Dynamic effects of psychiatric vulnerability, loneliness and isolation on distress during the first year of the COVID-19 pandemic [0.03%]
疫情期间精神脆弱性、孤独和隔离的动态效应研究
Lauren Y Atlas,Cristan Farmer,Jacob S Shaw et al.
Lauren Y Atlas et al.
The COVID-19 pandemic's impact on mental health is challenging to quantify because pre-existing risk, disease burden and public policy varied across individuals, time and regions. Longitudinal, within-person analyses can determine whether p...
Phenotypic divergence between individuals with self-reported autistic traits and clinically ascertained autism [0.03%]
具有自报孤独症特征的个体与临床诊断孤独症之间的表型差异
Sarah M Banker,Miles Harrington,Matthew Schafer et al.
Sarah M Banker et al.
While allowing for rapid recruitment of large samples, online research relies heavily on participants' self-reports of neuropsychiatric traits, foregoing the clinical characterizations available in laboratory settings. Autism spectrum disor...
Group arts interventions for depression and anxiety among older adults: a systematic review and meta-analysis [0.03%]
针对老年人的团体艺术干预对抑郁和焦虑的治疗效果：系统性评价及荟萃分析
Elizabeth A Quinn,Emma Millard,Janelle M Jones
Elizabeth A Quinn
In this systematic review and meta-analysis, we assessed the efficacy of group arts interventions, where individuals engage together in a shared artistic experience (for example, dance or painting), for reducing depression and anxiety among...
Opioid-induced neuroanatomical, microglial and behavioral changes are blocked by suvorexant without diminishing opioid analgesia [0.03%]
阿片类药物引起的神经解剖结构，小胶质细胞和行为变化被苏沃雷克斯阻断，并且不会降低阿片类药物的镇痛作用
Ronald McGregor,Ming-Fung Wu,Thomas C Thannickal et al.
Ronald McGregor et al.
Heroin use disorder in humans and chronic opioid administration to mice result in an increase in the number and a decrease in the size of detected hypocretin (Hcrt, or orexin) neurons. Chronic morphine administration to mice increases Hcrt ...
A systematic review of machine learning findings in PTSD and their relationships with theoretical models [0.03%]
系统回顾机器学习在创伤后应激障碍中的发现及其与理论模型的关系
Wivine Blekic,Fabien D&#x;Hondt,Arieh Y Shalev et al.
Wivine Blekic et al.
In recent years, the application of machine learning (ML) techniques in research on the prediction of post-traumatic stress disorder (PTSD) has increased. However, concerns regarding the clinical relevance and generalizability of ML finding...
A cognitive neural circuit biotype of depression showing functional and behavioral improvement after transcranial magnetic stimulation in the B-SMART-fMRI trial [0.03%]
贝-SMART-fMRI试验中经颅磁刺激后功能和行为改善的抑郁症认知神经环路亚型
Leonardo Tozzi,Claire Bertrand,Laura Michele Hack et al.
Leonardo Tozzi et al.
We previously identified a cognitive biotype of depression characterized by treatment resistance, impaired cognitive control behavioral performance and dysfunction in the cognitive control circuit, comprising the dorsolateral prefrontal cor...