Subtyping first-episode psychosis based on longitudinal symptom trajectories using machine learning [0.03%]
基于纵向症状轨迹利用机器学习对首发精神病进行亚型划分
Yanan Liu,Sara Jalali,Ridha Joober et al.
Yanan Liu et al.
Clinical course after first episode psychosis (FEP) is heterogeneous. Subgrouping and predicting longitudinal symptom trajectories after FEP may help develop personalized treatment approaches. We utilized k-means clustering to identify clus...
Canonical and non-canonical roles of oligodendrocyte precursor cells in mental disorders [0.03%]
寡突胶质前体细胞在精神疾病中的经典和非经典作用
Giulia Poggi,Giulia Treccani,Martina von der Bey et al.
Giulia Poggi et al.
Psychiatric research has shifted from a neuroncentric view to understanding mental disorders as disturbances of heterogeneous brain networks. Oligodendrocyte precursor cells (OPCs)- actively involved in the modulation of neuronal functions ...
Electrocardiography-derived autonomic profiles in depression and suicide risk with insights from the UK Biobank [0.03%]
基于英国生物银行的抑郁症和自杀风险的电导心律自主神经谱型研究
Samantha Weber,Mario Müller,Golo Kronenberg et al.
Samantha Weber et al.
The role of the autonomic nervous system (ANS) in depression and suicidality is multifaceted. This study examined whether distinct electrocardiography based ANS profiles exist, associated with a lifetime/recent at-risk cohort or a resilient...
Assessing the impact of AI on physician decision-making for mental health treatment in primary care [0.03%]
评估人工智能对全科医生心理健康治疗决策影响的方法论研究
Katie Ryan,Hyun-Joon Yang,Bohye Kim et al.
Katie Ryan et al.
AI models may soon be poised to recommend mental health treatments or referrals in primary care, yet little is known regarding their impact on physician decision-making. In this web-based study, primary care physicians (n = 420) were presen...
Examining measurement discrepancies in adolescent screen media activity with insights from the ABCD study [0.03%]
基于ABCD研究在青少年屏幕媒体活动测量差异中的见解
Yihong Zhao,Xuewei Han,Kara S Bagot et al.
Yihong Zhao et al.
Concerns about the accuracy of self-reported screen time persist due to discrepancies with objective measures. This study compared passive smartphone tracking via the "Effortless Assessment of Risk States'' (EARS) app with self-reported scr...
Identifying childhood correlates of adult purpose and meaning across 22 countries (Global Flourishing Study) [0.03%]
全球繁荣研究：识别22个国家中成人生活目标和意义的童年预测因素
Eric S Kim,Matt Bradshaw,R Noah Padgett et al.
Eric S Kim et al.
How might we cultivate a life imbued with purpose and meaning? Though common experience indicates purpose and meaning are inherently important, empirical evidence confirms they are also linked to improved health/well-being. However, childho...
When the glass is half full: early life experiences and adult optimism in 22 countries [0.03%]
当人生半杯酒——22国成人乐观情绪与其早期经历的关系
Ying Chen,Laura D Kubzansky,Eric S Kim et al.
Ying Chen et al.
Little is known about early-life experiences that may lead to higher optimism levels in adulthood. Using data from 202,898 adults in 22 countries, we evaluated childhood candidate antecedents of optimism. We examined the associations betwee...
Impaired mnemonic pattern separation associated with PTSD symptoms paradoxically improves with regular cannabis use [0.03%]
大麻定期使用与PTSD症状相关的记忆模式分离障碍的改善有关
Jacob Ross,Bruna Cuccurazzu,Dylan Delmar et al.
Jacob Ross et al.
Posttraumatic stress disorder (PTSD) is associated with poor hippocampal function and disrupted pattern recognition. Cannabis use is highly prevalent in individuals with PTSD, yet the impact on these cognitive functions is poorly understood...
Assessing seasonal and weather effects on depression and physical activity using mobile health data [0.03%]
基于移动健康数据评估季节和天气对抑郁及身体活动的影响
Yuezhou Zhang,Amos A Folarin,Yatharth Ranjan et al.
Yuezhou Zhang et al.
Seasonal and weather changes can significantly impact depression severity, yet findings remain inconsistent across populations. This study explored depression variations across the seasons and the interplays between weather changes, physica...
Probiotics reduce negative mood over time: the value of daily self-reports in detecting effects [0.03%]
益生菌可改善心情：每日自我报告的价值性不容忽视
Katerina V-A Johnson,Laura Steenbergen
Katerina V-A Johnson
The burgeoning field of the microbiome-gut-brain axis has inspired research into how the gut microbiome can affect human emotion. Probiotics offer ways to investigate microbial-based interventions but results have been mixed, with more evid...