Optimum flux rerouting for efficient production of naringenin from acetate in engineered Escherichia coli [0.03%]
通过工程化大肠杆菌高效产生柚皮素的最佳通量重新分布研究
Dong Hwan Kim,Hyun Gyu Hwang,Gyoo Yeol Jung
Dong Hwan Kim
Background: Microbial production of naringenin has received much attention owing to its pharmaceutical applicability and potential as a key molecular scaffold for various flavonoids. In the microbial fermentation, a cheap...
Secretion of collagenases by Saccharomyces cerevisiae for collagen degradation [0.03%]
分泌胶原酶的酵母菌种及其降解胶原的方法及试剂组合物
Han Xiao,Xiufang Liu,Yunzi Feng et al.
Han Xiao et al.
Background: The production and processing of animal-based products generates many collagen-rich by-products, which have received attention both for exploitation to increase their added value and to reduce their negative e...
Inhibition of monogalactosyldiacylglycerol synthesis by down-regulation of MGD1 leads to membrane lipid remodeling and enhanced triacylglycerol biosynthesis in Chlamydomonas reinhardtii [0.03%]
通过MGD1的转录后调控来抑制单半乳糖基二酰甘油合成，进而对绿藻细胞膜脂质进行重塑并提高三酰甘油脂类生物合成
Jun-Woo Lee,Min-Woo Lee,Chun-Zhi Jin et al.
Jun-Woo Lee et al.
Background: Membrane lipid remodeling involves regulating the physiochemical modification of cellular membranes against abiotic stress or senescence, and it could be a trigger to increase neutral lipid content. In algae a...
Acetoin production from lignocellulosic biomass hydrolysates with a modular metabolic engineering system in Bacillus subtilis [0.03%]
采用模块化代谢工程技术生产丁二酮
Qiang Wang,Xian Zhang,Kexin Ren et al.
Qiang Wang et al.
Background: Acetoin (AC) is a vital platform chemical widely used in food, pharmaceutical and chemical industries. With increasing concern over non-renewable resources and environmental issues, using low-cost biomass for ...
Sorbicillinoids hyperproduction without affecting the cellulosic enzyme production in Trichoderma reesei JNTR5 [0.03%]
里氏木霉JNTR5高产 Sorbicillinoids且不影响纤维素酶产生
Chengcheng Li,Ruihan Gu,Fengming Lin et al.
Chengcheng Li et al.
Background: Microbial production of bioactive secondary metabolites is challenging as most of the encoding genes are silent; and even if they are activated, the biosynthetic pathways are usually complex. Sorbicillinoids w...
Metabolic engineering of Escherichia coli for direct production of vitamin C from D-glucose [0.03%]
大肠杆菌从D-葡萄糖直接生产维生素C的代谢工程研究
Yong-Sheng Tian,Yong-Dong Deng,Wen-Hui Zhang et al.
Yong-Sheng Tian et al.
Background: Production of vitamin C has been traditionally based on the Reichstein process and the two-step process. However, the two processes share a common disadvantage: vitamin C cannot be directly synthesized from D-...
Improved energy efficiency in microbial fuel cells by bioethanol and electricity co-generation [0.03%]
利用微生物燃料电池同时制备生物乙醇和发电提高能量效率
Rong Xie,Shuang Wang,Kai Wang et al.
Rong Xie et al.
Background: Microbial electricity production has received considerable attention from researchers due to its environmental friendliness and low price. The increase in the number of intracellular electrons in a microbial f...
Lysophosphatidic acid acyltransferase 2 and 5 commonly, but differently, promote seed oil accumulation in Brassica napus [0.03%]
芸苔素酰基转移酶2和5共同但不同地促进油菜籽油积累
Kai Zhang,Jianjie He,Yongtai Yin et al.
Kai Zhang et al.
Background: Increasing seed oil content (SOC) of Brassica napus has become one of the main plant breeding goals over the past decades. Lysophosphatidic acid acyltransferase (LPAT) performs an important molecular function ...
Identification and combinatorial engineering of indole-3-acetic acid synthetic pathways in Paenibacillus polymyxa [0.03%]
芽胞杆菌种多粘类芽孢杆菌吲哚乙酸合成途径的鉴定与组合代谢工程改造
Huimin Sun,Jikun Zhang,Wenteng Liu et al.
Huimin Sun et al.
Background: Paenibacillus polymyxa is a typical plant growth-promoting rhizobacterium (PGPR), and synthesis of indole-3-acetic acid (IAA) is one of the reasons for its growth-promoting capacity. The synthetic pathways of ...
In silico-guided metabolic engineering of Bacillus subtilis for efficient biosynthesis of purine nucleosides by blocking the key backflow nodes [0.03%]
基于计算机的色氨酸代谢工程研究阻断关键反向流量节点高效生物合成嘌呤核糖核苷酸
Aihua Deng,Qidi Qiu,Qinyun Sun et al.
Aihua Deng et al.
Background: Purine nucleosides play essential roles in cellular physiological processes and have a wide range of applications in the fields of antitumor/antiviral drugs and food. However, microbial overproduction of purin...