Lucia Iafrate,Maria Cristina Benedetti,Samantha Donsante et al.
Lucia Iafrate et al.
Bone pain typically occurs immediately following skeletal damage with mechanical distortion or rupture of nociceptive fibres. The pain mechanism is also associated with chronic pain conditions where the healing process is impaired. Any load...
Physiologically relevant platform for an advanced in vitro model of the vascular wall: focus on in situ fabrication and mechanical maturation [0.03%]
一种用于血管壁高级体外模型的生理相关平台:重点在于原位制造和机械成熟化
The mechanical stimulation applied on engineered vascular constructs in perfusion bioreactors has been shown to be beneficial for their maturation. The level of mechanical stimulation applied on these constructs depends on the flow paramete...
A human Caco-2-based co-culture model of the inflamed intestinal mucosa for particle toxicity studies [0.03%]
一种基于人类Caco-2共培养的发炎肠粘膜模型用于颗粒毒性研究
The intestinal barrier is a complex interface of the human body, possessing the largest contact surface to nutrients and antigens and containing a major part of the immune system. It has to deal with continuous exposure to a broad mixture o...
Development of a tissue-engineered skin model with epidermal, dermal and hypodermal components [0.03%]
一种具有表皮、真皮和皮下组织成分的组织工程皮肤模型的构建
Tissue-engineered models of skin have evolved over the past 50 years, have successfully been translated to clinical use and continue to be improved using new technologies. However, very few of these constructs incorporate a hypodermal compo...
Introducing CELLBLOKS®: a novel organ-on-a-chip platform allowing a plug-and-play approach towards building organotypic models [0.03%]
介绍CELLBLOKS®:一种新颖的器官芯片平台,可通过即插即用方法构建组织特异性模型
Human organs are structurally and functionally complex systems. Their function is driven by the interactions between many specialised cell types, which is difficult to unravel on a standard Petri dish format. Conventional "Petri dish" appro...