Depression in Sjögren's syndrome mediates the relationship between pain, fatigue, sleepiness, and overall quality of life [0.03%]
抑郁症在舍格伦综合征中介导了疼痛、疲劳、嗜睡和整体生活质量之间的关系
Tiago Costa,Stephen P Rushton,Stuart Watson et al.
Tiago Costa et al.
Objectives: Sjögren's syndrome (SS) includes many extra-glandular symptoms such as fatigue, pain, sleepiness and depression, which impact on quality of life (QoL). These symptoms also influence each other and could be li...
mRNA vaccine against fibroblast activation protein ameliorates murine models of inflammatory arthritis [0.03%]
针对成纤维细胞活化蛋白的mRNA疫苗可改善关节炎小鼠模型的症状
Xiaowei Zhang,Antony Jozic,Pingfang Song et al.
Xiaowei Zhang et al.
Objective: Synovial fibroblasts in patients with rheumatoid arthritis (RA) contribute substantially to the perpetuation of synovitis and invasion to cartilage and bone, and are potential therapeutic targets. Fibroblast ac...
Seronegative enthesoarthritis as the first presentation of the atrial myxoma [0.03%]
空泡性风湿病作为房室黏液瘤的首发表现
Bonomi Francesco,Orlandi Martina,Conforti Maria Letizia et al.
Bonomi Francesco et al.
Atrial myxoma (AM) is the most common primary cardiac tumor. Its clinical presentation can be highly heterogeneous and can be characterized by many constitutional manifestations and development of rheumatologic symptoms.We report the case o...
Michelle Petri,Chenglong Fang,Daniel W Goldman
Michelle Petri
Background and objective: East Asian systemic lupus erythematosus (SLE) is under represented in lupus cohorts outside of East Asia. We asked whether lupus nephritis was more common and more severe in East Asians than in o...
2022 Chinese guideline for the management of pregnancy and reproduction in systemic lupus erythematosus [0.03%]
2022 中国系统性红斑狼疮患者妊娠管理指南
Xinping Tian,Jiuliang Zhao,Yijun Song et al.
Xinping Tian et al.
Systemic lupus erythematosus (SLE), a prevalent autoimmune disease predominantly affecting women of childbearing age, presents ongoing challenges despite notable advances in diagnosis and treatment. Although survival rates for SLE patients ...
Ram P Singh,David S Bischoff,Satendra S Singh et al.
Ram P Singh et al.
In autoimmune rheumatic diseases, immune hyperactivity and chronic inflammation associate with immune dysregulation and the breakdown of immune self-tolerance. A continued, unresolved imbalance between effector and regulatory immune respons...
A rare condition that mimic myopathy: Late-onset glutaric acidaemia type II [0.03%]
罕见的肌病样条件：晚发型戊二酸尿症二期
Jianwen Liu,Chenmin Wu,Fei Gao et al.
Jianwen Liu et al.
Improve quality of patient care for systemic lupus erythematosus in China by enhancing the construction of Centers of Excellence [0.03%]
通过加强优质医疗中心建设提高中国系统性红斑狼疮患者护理质量
Mengtao Li,Xinping Tian,Qian Wang et al.
Mengtao Li et al.
Leila Khalili,Wei Tang,Anca D Askanase
Leila Khalili
Antonio La Cava
Antonio La Cava
In systemic lupus erythematosus (SLE), T regulatory cells (Tregs) contribute to the inhibition of autoimmune responses by suppressing self-reactive immune cells. Interleukin (IL)-2 plays an essential role in the generation, function and hom...