Mycobacterial metabolic model development for drug target identification [0.03%]
结核菌代谢模型在药物作用靶点鉴定中的应用
Bridget P Bannerman,Alexandru Oarga,Jorge Júlvez
Bridget P Bannerman
Antibiotic resistance is increasing at an alarming rate, and three related mycobacteria are sources of widespread infections in humans. According to the World Health Organization, Mycobacterium leprae, which causes leprosy, is still endemic...
The first genome assembly of the amphibian nematode parasite (Aplectana chamaeleonis) [0.03%]
首个人类两栖线虫寄生虫基因组草图（蝘皮线虫属）
Lei Han,Tianlu Liu,Fengping He et al.
Lei Han et al.
Cosmocercoid nematodes are common parasites of the digestive tract of amphibians. Genomic resources are important for understanding the evolution of a species and the molecular mechanisms of parasite adaptation. So far, no genome resource o...
Balan Ramesh,Clay M Small,Hope Healey et al.
Balan Ramesh et al.
The Gulf pipefish Syngnathus scovelli has emerged as an important species for studying sexual selection, development, and physiology. Comparative evolutionary genomics research involving fishes from Syngnathidae depends on having a high-qua...
Tick abundance, diversity and pathogen data collected by the National Ecological Observatory Network [0.03%]
国家生态观测网络采集的蜱类数量、多样性和病原体数据
Sara H Paull,Katherine M Thibault,Abigail L Benson
Sara H Paull
Cases of tick-borne diseases have been steadily increasing in the USA, owing in part to tick range expansion, land cover and associated host population changes, and habitat fragmentation. However, the relative importance of these and other ...
NiemaGraphGen: A memory-efficient global-scale contact network simulation toolkit [0.03%]
NiemaGraphGen：一种高效的大规模接触网络模拟工具包
Niema Moshiri
Niema Moshiri
Epidemic simulations require the ability to sample contact networks from various random graph models. Existing methods can simulate city-scale or even country-scale contact networks, but they are unable to feasibly simulate global-scale con...
Genome assembly of the roundjaw bonefish (Albula glossodonta), a vulnerable circumtropical sportfish [0.03%]
圆吻骨鱼（Albula glossodonta）的基因组组装，一种脆弱的环热带运动鱼类
Brandon D Pickett,Sheena Talma,Jessica R Glass et al.
Brandon D Pickett et al.
The roundjaw bonefish, Albula glossodonta, is the most widespread albulid in the Indo-Pacific and is vulnerable to extinction. We assembled the genome of a roundjaw bonefish from Hawai'i, USA, which will be instrumental for effective transb...
Atria: an ultra-fast and accurate trimmer for adapter and quality trimming [0.03%]
Atria：一种超快且准确的接头和质量修剪工具
Jiacheng Chuan,Aiguo Zhou,Lawrence Richard Hale et al.
Jiacheng Chuan et al.
With advances in next-generation sequencing, adapters attached to reads and low-quality bases directly and implicitly hinder downstream analysis. For example, they can produce false-positive single nucleotide polymorphisms (SNP), and genera...
The genome of Tripterygium wilfordii and characterization of the celastrol biosynthesis pathway [0.03%]
黄杜灵瓜提取物基因组及Celastrol生物合成途径特征分析
Tianlin Pei,Mengxiao Yan,Yu Kong et al.
Tianlin Pei et al.
Tripterygium wilfordii is a vine from the Celastraceae family that is used in traditional Chinese medicine (TCM). The active ingredient, celastrol, is a friedelane-type pentacyclic triterpenoid with putative roles as an antitumor, immunosup...
A highly contiguous, scaffold-level nuclear genome assembly for the fever tree (Cinchona pubescens Vahl) as a novel resource for Rubiaceae research [0.03%]
一份高度连续的温树（Cinchona pubescens Vahl）核基因组支架水平组装作为番荔枝科研究的新资源
Nataly Allasi Canales,Oscar A Pérez-Escobar,Robyn F Powell et al.
Nataly Allasi Canales et al.
The Andean fever tree (Cinchona L.; Rubiaceae) is a source of bioactive quinine alkaloids used to treat malaria. C. pubescens Vahl is a valuable cash crop within its native range in northwestern South America, however, genomic resources are...
PhysiPKPD: A pharmacokinetics and pharmacodynamics module for PhysiCell [0.03%]
PhysiPKPD：PhysiCell 的药代动力学和药效学模块
Daniel Bergman,Lauren Marazzi,Mukti Chowkwale et al.
Daniel Bergman et al.
Pharmacokinetics and pharmacodynamics (PKPD) are key considerations in any study of molecular therapies. It is thus imperative to factor their effects into any in silico model of biological tissue involving such therapies. Furthermore, crea...