Characterization of nucleosome sediments for protein interaction studies by solid-state NMR spectroscopy [0.03%]
固体核磁共振光谱法表征用于蛋白质相互作用研究的核小体沉淀物
Ulric B le Paige,ShengQi Xiang,Marco M R M Hendrix et al.
Ulric B le Paige et al.
Regulation of DNA-templated processes such as gene transcription and DNA repair depend on the interaction of a wide range of proteins with the nucleosome, the fundamental building block of chromatin. Both solution and solid-state NMR spectr...
Fragile protein folds: Sequence and environmental factors affecting the equilibrium of two interconverting, stably folded protein conformations [0.03%]
脆弱的蛋白质折叠：影响两种可互换、稳定折叠的蛋白质构象平衡的序列和环境因素
Xingjian Xu,Igor Dikiy,Matthew R Evans et al.
Xingjian Xu et al.
Recent research on fold-switching metamorphic proteins has revealed some notable exceptions to Anfinsen's hypothesis of protein folding. We have previously described how a single point mutation can enable a well-folded protein domain, one o...
Overhauser dynamic nuclear polarization (ODNP)-enhanced two-dimensional proton NMR spectroscopy at low magnetic fields [0.03%]
过度霍斯特动态核偏磁化低温磁场下二维氢质子核磁共振谱学研究
Timothy J Keller,Thorsten Maly
Timothy J Keller
The majority of low-field Overhauser dynamic nuclear polarization (ODNP) experiments reported so far have been 1D NMR experiments to study molecular dynamics and in particular hydration dynamics. In this work, we demonstrate the application...
Using delayed decoupling to attenuate residual signals in editing filters [0.03%]
在编辑滤波器中使用延迟解耦来衰减残余信号
Kenneth A Marincin,Indrani Pal,Dominique P Frueh
Kenneth A Marincin
Isotope filtering methods are instrumental in biomolecular nuclear magnetic resonance (NMR) studies as they isolate signals of chemical moieties of interest within complex molecular assemblies. However, isotope filters suppress undesired si...
DeerLab: a comprehensive software package for analyzing dipolar electron paramagnetic resonance spectroscopy data [0.03%]
DeerLab：用于分析偶极电子顺磁共振光谱数据的综合软件包
Luis Fábregas Ibáñez,Gunnar Jeschke,Stefan Stoll
Luis Fábregas Ibáñez
Dipolar EPR spectroscopy (DEER and other techniques) enables the structural characterization of macromolecular and biological systems by measurement of distance distributions between unpaired electrons on a nanometer scale. The inference of...
Timothy Crawley,Arthur G Palmer rd
Timothy Crawley
The ability to make robust inferences about the dynamics of biological macromolecules using NMR spectroscopy depends heavily on the application of appropriate theoretical models for nuclear spin relaxation. Data analysis for NMR laboratory-...
Approximate Representations of Shaped Pulses Using the Homotopy Analysis Method [0.03%]
同伦分析法在刻画整形脉冲信号中的应用
Timothy Crawley,Arthur G Palmer rd
Timothy Crawley
The evolution of nuclear spin magnetization during a radiofrequency pulse in the absence of relaxation or coupling interactions can be described by three Euler angles. The Euler angles in turn can be obtained from the solution of a Riccati ...
Competing Transfer Pathways in Direct and Indirect Dynamic Nuclear Polarization MAS NMR Experiments on HIV-1 Capsid Assemblies: Implications for Sensitivity and Resolution [0.03%]
用于HIV-1衣壳组装体的直接和间接动态核磁共振极化实验中的竞争转移途径：关于灵敏度和分辨率的影响
Ivan V Sergeyev,Caitlin M Quinn,Jochem Struppe et al.
Ivan V Sergeyev et al.
Dynamic nuclear polarization-enhanced (DNP) magic angle spinning (MAS) NMR of biological systems is a rapidly growing field. Large signal enhancements make the technique particularly attractive for signal-limited cases, such as studies of c...