Addressing the anthrax threat: A synthesis of clinical management and public health priorities [0.03%]
应对炭疽威胁：临床管理和公共卫生重点的综合措施
Gian Marco Ludovici,Paola Amelia Tassi,Alba Iannotti et al.
Gian Marco Ludovici et al.
Functional cure for chronic hepatitis B: A state of immune control over cccDNA persistence [0.03%]
慢性乙型肝炎的功能治愈：cccDNA持续存在的免疫控制状态
Kunyu Zhao,Lili Wu,Yu Wu et al.
Kunyu Zhao et al.
Functional (clinical) cure is considered a desirable therapeutic endpoint of antiviral therapy for chronic hepatitis B (CHB). Recent studies have detected transcriptionally active covalently closed circular DNA (cccDNA) and integrated hepat...
Temporal trends and clinical outcomes of antiretroviral therapy initiation and regimens in treatment-naive people with HIV: A real-world study at a tertiary specialist hospital in Beijing, China [0.03%]
中国北京一家三级专科医院HIV抗病毒治疗初治患者的治疗启动趋势及临床结局：一项真实世界研究
Jiantao Fu,Ying Liu,Yifan Guo et al.
Jiantao Fu et al.
Background: The WHO and international treatment guidelines recommend rapid initiation of antiretroviral therapy (ART) for all treatment-naive (TN) people living with human immunodeficiency virus (HIV) (PLWH). However, dat...
Quantitative real-time PCR in the diagnosis of opportunistic infections in immunocompromised patients: Diagnostic performance, clinical utility, and future directions [0.03%]
定量实时PCR在免疫缺陷患者机会性感染诊断中的应用：诊断性能、临床效用及未来方向
Meganathan Karthikeyan,Praveen Kumar Chandra Sekar,Ramakrishnan Veerabathiran
Meganathan Karthikeyan
Opportunistic infections (OIs) remain a major cause of morbidity and mortality among immunocompromised individuals, and delayed or inaccurate diagnosis can rapidly lead to adverse clinical outcomes. This narrative review critically evaluate...
SLC3A2 promotes early-stage of Zika virus infection in human placental cells and astrocytes [0.03%]
SLC3A2促进Zika病毒感染人胎盘细胞和星形胶质细胞的早期阶段
Zhilu Chen,Daobin Feng,Jian Liu et al.
Zhilu Chen et al.
Background: Zika virus (ZIKV) has been associated with neonatal microcephaly or atypical Guillain-Barré syndrome in adults since 2016. However, despite considerable progress in understanding the biology and pathogenesis ...
Yibin Zhu,Jichen Niu,Gong Cheng
Yibin Zhu
Diagnostic challenges from concurrent seronegative HCV and HIV antibody seroreversion in a person living with HIV: A case report [0.03%]
一名HIV感染者的HCV和HIV抗体同时转阴的诊断挑战——一例报告
Rosamaria Tedeschi,Giancarlo Basaglia,Ornella Schioppa
Rosamaria Tedeschi
Although hepatitis C virus (HCV) infection is typically diagnosed by anti-HCV antibody testing, rare cases of seronegative HCV infection, defined by detectable HCV ribonucleic acid (RNA) in the absence of antibodies, have been reported in a...
Comparing virulence profile of dominant emm 1 and emm 12 group A streptococcus strains associated with scarlet fever in Shanghai [0.03%]
上海猩红热的优势型emm 1和emm 12群A链球菌的毒力谱系比较分析
Xingyu Zhou,Jiehao Cai,Yanyan Lu et al.
Xingyu Zhou et al.
Background: An increased incidence of group A Streptococcus-related scarlet fever has been observed in Shanghai since 2011, characterized by the co-circulation of both emm12 and emm1 strains. The comparative virulence pot...
Wanying Zhang,Mo Zhou,Jingliang Chen et al.
Wanying Zhang et al.
The human immunodeficiency virus (HIV) epidemic poses a significant threat to global human health annually. Although antiretroviral therapy can control HIV viremia and delay disease progression, it cannot eliminate the viral reservoir. Peop...