Reviving Dormant Immunity: Millimeter Waves Reprogram the Immunosuppressive Microenvironment to Potentiate Immunotherapy without Obvious Side Effects [0.03%]
毫米波重编程免疫抑制微环境 无需伴随明显副作用即可增强免疫疗法效力
Zhenqi Jiang,Rui Jing,Ozioma Udochukwu Akakuru et al.
Zhenqi Jiang et al.
Addressing the variability in cancer immunotherapeutic outcomes among patients and the challenge of devising safe strategies to overcome immune evasion in solid tumors are crucial in advancing cancer therapy. This study investigated the ant...
Multimodal Imaging-Based Cerebral Blood Flow Prediction Model Development in Simulated Microgravity [0.03%]
基于多模态影像的脑血流预测模型在模拟失重环境中的开发
Linkun Cai,Yawen Liu,Kai Li et al.
Linkun Cai et al.
Background: Abnormal alterations in cerebral blood flow (CBF) have been implicated in cognitive decline and neurodegeneration. Maintaining adequate CBF in astronauts during long-duration microgravity is therefore crucial for the success of ...
Tunable Neuromorphic Computing for Dynamic Multi-Timescale Sensing in Motion Recognition [0.03%]
用于运动识别动态多时间尺度感应的可调神经形态计算
Ruitong Bie,Xi Chen,Zhe Yang et al.
Ruitong Bie et al.
Motion recognition, especially the distinction between high-speed and low-speed movements, is a challenging computational task that typically requires substantial resources. The extensive response range required to detect such variations in...
Bimodal Tactile Tomography with Bayesian Sequential Palpation for Intracavitary Microstructure Profiling and Segmentation [0.03%]
基于贝叶斯顺序触诊的双模态触觉层析成像的腔内微结构表征与分割
Wenchao Yue,Chao Xu,Tao Zhang et al.
Wenchao Yue et al.
Robotic palpation for in situ tissue biomechanical evaluation is crucial for disease diagnosis, especially in luminal organs. However, acquiring real-time information about the tissue's interaction state and physical characteristics remains...
Advanced Microrobots Driven by Acoustic and Magnetic Fields for Biomedical Applications [0.03%]
声磁场驱动微米机器人在生物医学中的应用研究进展
Tingting Wang,Zhuo Chen,Qiang Huang et al.
Tingting Wang et al.
Microrobots driven by magnetic and acoustic fields have shown great potential in multiple biomedical applications due to their excellent biocompatibility, wireless actuation, access to confined environments, and tissue penetration. A single...
MEA-Based Graph Deviation Network for Early Autism Syndrome Signatures in Human Forebrain Organoids [0.03%]
基于MEA的图偏差网络在人脑类器官自闭症谱系障碍早期标志物中的应用研究
Arianna Mencattini,Giorgia Curci,Alessia Riccardi et al.
Arianna Mencattini et al.
Multi-electrode arrays (MEAs) are a key enabling technology in the development of cybernetic systems, as they provide a means to understand and control the activity of neural populations linking brain microtissue dynamics with electronic sy...
Carrier-Free Peptide-Daunorubicin-Small Interfering RNA Nanoassembly for Targeted Therapy of Acute Myeloid Leukemia [0.03%]
靶向治疗急性髓系白血病的肽-柔红霉素-小干扰核酸纳米组装体
Haiyin Yang,Xi Yu,Zhitong Guo et al.
Haiyin Yang et al.
Acute myeloid leukemia (AML) continues to represent a substantial unmet therapeutic need in clinical practice. In recent years, peptide-drug conjugates and small interfering RNA (siRNA) drugs have gained considerable attention due to their ...
Magnetically Actuated Soft Electrodes for Multisite Bioelectrical Monitoring of Ex Vivo Tissues [0.03%]
体外组织多点生物电监测的磁驱动软电极
Qianbi Peng,Jianping Huang,Chenyang Li et al.
Qianbi Peng et al.
Multisite electrophysiological monitoring of ex vivo tissues and organ models is essential for basic research and drug toxicity evaluation. However, conventional microelectrode arrays with fixed positions and rigid structures are insufficie...
Integrated Piezoelectric Vibration and In Situ Force Sensing for Low-Trauma Tissue Penetration [0.03%]
集成了压电振动和原位力感知的低创伤组织穿刺技术
Bingze He,Yao Guo,Guangzhong Yang
Bingze He
Precision-controlled microscale manipulation tasks-including neural probe implantation, ophthalmic surgery, and cell membrane puncture-often involve minimally invasive membrane penetration techniques with real-time force feedback to minimiz...
Neuroanatomy-Informed Brain-Machine Hybrid Intelligence for Robust Acoustic Target Detection [0.03%]
基于神经解剖学的脑机混合智能在鲁邦声学目标检测中的应用
Jianting Shi,Jiaqi Wang,Weijie Fei et al.
Jianting Shi et al.
Sound target detection (STD) plays a critical role in modern acoustic sensing systems. However, existing automated STD methods show poor robustness and limited generalization, especially under low signal-to-noise ratio (SNR) conditions or w...