Nodular secondary syphilis in a patient who was immunocompetent: a sporotrichoid masquerader with synchronous primary lesion [0.03%]
一位免疫功能正常的患者的结节性二期梅毒:与原发性病变同时存在的绳索状假性孢子菌病
Jacopo Tartaglia,Francesco Fortarezza,Monica Ponzano et al.
Jacopo Tartaglia et al.
We report a case of nodular secondary syphilis in an immunocompetent man presenting with concurrent chancre, macular rash and sporotrichoid nodules. Dermoscopy and histology raised suspicion for pseudolymphoma, but serology and Warthin-Star...
Clinical description and management of two terbinafine-resistant cases of tinea caused by Trichophyton indotineae from Finland [0.03%]
特比萘芬耐药型皮肤丝孢霉病2例的临床和治疗描述
Niina Kantola,Outi Varpuluoma,Elina Aho-Laukkanen et al.
Niina Kantola et al.
The first reports of terbinafine-resistant Trichophyton indotineae emerged from India in late 2017. Since then, superficial fungal infections caused by terbinafine-resistant T. indotineae have been increasingly reported in European countrie...
A survey of UK-based dermatologists and Outpatient Parenteral Antimicrobial Therapy centres to evaluate the use of intravenous antibiotics as a treatment for hidradenitis suppurativa [0.03%]
一项针对英国皮肤科医生和门诊抗菌静脉用药中心的调查 评估用于治疗化脓性汗腺炎的静脉注射抗生素的使用情况
Mun Wai Lam,Ryan A Hamilton,Helena A White et al.
Mun Wai Lam et al.
Background: Case series have indicated that intravenous antibiotics may be effective in severe hidradenitis suppurativa (HS) treatment. This treatment approach is excluded from the British Association of Dermatologists UK...
Seen on screen, missed in clinic: educational pearls from House M.D. - a reflective educational article on fictional cases in dermatology [0.03%]
从《豪斯医生》看皮肤科的临床教学——兼论电视剧与医学教育的关系
Mohammed Shanshal
Mohammed Shanshal
Dermatological clues are frequently overlooked in complex clinical presentations, both in real life and fictional portrayals. This article explores how seven dramatic cases from the television show House M.D. illustrate missed or delayed di...
Improvement of recalcitrant Hailey-Hailey disease (ATP2C1-nonsyndromic epidermal differentiation disorder) with topical ruxolitinib 1.5% cream [0.03%]
外用鲁索利替尼乳膏治疗棘手的哈莱-哈莱病(ATP2C1非综合表皮分化障碍)疗效良好
Alyssa Jobe,Ashley Ng,Shanelle Briggs et al.
Alyssa Jobe et al.
ATP2C1-nonsyndromic epidermal differentiation disorder, also known as familial benign chronic pemphigus or Hailey-Hailey disease, is a rare autosomal dominant acantholytic disorder characterized by relapsing and remitting painful vesicles a...
A rare case of acute generalized exanthematous pustulosis-like Sweet syndrome [0.03%]
一例类似急性广泛性发疱性毛囊炎的Sweet综合征罕见病例报告
Brandon C E Hu,Bowen Xia,Paul Curnow et al.
Brandon C E Hu et al.
Acute generalized exanthematous pustulosis (AGEP) is a pustular drug eruption characterized by superficial pustules, commonly caused by β-lactam antibiotics. Management of AGEP involves discontinuation of the offending medication and suppo...
Do remote clinical trials offer carbon savings while maintaining research quality? Experiences from the Eczema Bathing Study [0.03%]
远程临床试验能否在保证研究质量的同时减少碳排放?来自eczema bathing study的经验
Vaibhav Chaganti,Emma L Campbell,Jessica Griffiths et al.
Vaibhav Chaganti et al.
Background: Traditional clinical trials contribute significantly to the carbon footprint of healthcare. They are also expensive and take a long time to complete. Remote trials could offer part of the solution. They are a ...
The ulcer that would not heal: a rare cutaneous clue to miliary tuberculosis [0.03%]
经久不愈的溃疡:粟粒性肺结核的罕见皮肤线索
Elisha Shrestha,Ashish Tamang,Namrata Pradhan et al.
Elisha Shrestha et al.
Cutaneous tuberculosis (TB) is a rare manifestation of extrapulmonary TB, accounting for only 1-1.5% of cases. Among its various forms, cutaneous miliary TB is exceptionally uncommon and often presents with nonspecific clinical features. Th...
Gustavo Almeida-Silva,Joana Antunes
Gustavo Almeida-Silva
We report the first case of stress-induced rupioid psoriasis, a rare and severe hyperkeratotic variant of psoriasis, arising after the sudden loss of a close relative. The patient achieved remarkable clearance with ustekinumab, highlighting...
Sensoriality of emollient creams: can sensory experience compromise blinding in trials? [0.03%]
润肤霜的感觉属性:感觉体验能否影响试验的双盲性?
Jean-Matthieu LOrphelin,Cécile Morice,Johan Gardères et al.
Jean-Matthieu LOrphelin et al.
Background: Regular application of emollients, particularly those that enhance the skin's acid mantle and promote ceramide production, can help restore skin barrier integrity, reduce inflammation and prevent disease flare...