Effect of topical treatment with 7.5% urea in Ichthyosis Vulgaris: A randomized, controlled, double blinded, split body study evaluating the effect of urea cream compared to the vehicle (moisturizing) cream [0.03%]
局部外用7.5%尿素治疗寻常鱼鳞病:一项随机对照双盲半脸研究评估尿素乳膏与安慰剂(保湿)乳膏的效果
I L H Dorf,M S Lunen,U Koppelhus
I L H Dorf
Background: Ichthyosis Vulgaris (IV) is a common genetic skin disease, characterized by dry, scaling skin and itch. Urea cream has been a central part of IV treatment for decades, but only few studies have evaluated the e...
Health utilities for non-melanoma skin cancers and pre-cancerous lesions: A systematic review [0.03%]
非黑色素瘤皮肤癌和癌前病变的健康效用:系统评价
C So,A E Cust,L G Gordon et al.
C So et al.
Background: Non-melanoma skin cancers (NMSCs) are common and consume many healthcare resources. A health utility is a single preference-based value for assessing health-related quality of life, which can be used in econom...
Do patient characteristics matter when calculating sample size for eczema clinical trials? [0.03%]
特应性皮炎临床试验样本量计算中需要考虑患者特征吗?
L Howells,S Gran,J R Chalmers et al.
L Howells et al.
Background: The Patient-Oriented Eczema Measure (POEM) is the core outcome instrument recommended for measuring patient-reported atopic eczema symptoms in clinical trials. To ensure that the statistical significance of cl...
Skin cancers in skin types IV-VI: Does the Fitzpatrick scale give a false sense of security? [0.03%]
皮肤类型IV-VI的皮肤癌:Fitzpatrick量表是否带来了虚假的安全感?
P Goon,C Banfield,O Bello et al.
P Goon et al.
The Fitzpatrick scale has been in use for skin colour typing according to the tanning potential of skin since its inception in 1975-1976. Thomas Fitzpatrick developed the scale to classify persons with 'white skin' in order to select the co...
The spectrum of skin-related conditions in primary care during 2015-2019-A Finnish nationwide database study [0.03%]
2015年至2019年基层医疗中皮肤病状况的谱系——一项基于芬兰全国数据库的研究
A Salava,A Oker-Blom,A Remitz
A Salava
Background: Skin-related conditions are the frequent cause of doctors' consultations in primary care. Methods: Based on nationwide data...
Clinical outcomes at 1 year in early Psoriasis Area and Severity Index responders compared with non-responders: Subgroup analysis of UNCOVER-3 trial [0.03%]
与UNCOVER-3试验非应答者相比,早期PASI应答者的临床结局一年时的亚组分析
D Rosmarin,S Smith,D Shrom et al.
D Rosmarin et al.
K Kashiwada-Nakamura,T M Myangat,I Kajihara et al.
K Kashiwada-Nakamura et al.
Background: Deficiency of DNA mismatch repair (MMR) induces microsatellite instability (MSI). Pembrolizumab, an antibody targeting PD-1 (an immune checkpoint inhibitor), is more effective against MMR-deficient tumours tha...
M Haq,Y Reyal,N Tiffin et al.
M Haq et al.
We present a case of a 54-year-old male with multiple myeloma (MM) who presented with widespread pruritic erythematous lesions following ixazomib treatment. This occurred after his third cycle of treatment with ixazomib, thalidomide and dex...
Case Reports
Skin health and disease. 2021 Jun 30;1(3):e57. DOI:10.1002/ski2.57 2021
Prurigo strophulus: Epidemiological, clinical aspects and environmental factors among children in Yaoundé, Cameroon (Sub-Saharan Africa) [0.03%]
流行病学、临床表现及环境因素对喀麦隆雅温得地区(撒哈拉以南非洲)儿童瘙痒皮疹的影响
E A Kouotou,U Nguena Feungue,A Engolo Fandio et al.
E A Kouotou et al.
Background: Prurigo Strophulus (PS) is a chronic and recurrent inflammatory disease caused by a hypersensitivity reaction to arthropod bites. The objective of this study was to determine the prevalence of PS and its clini...
Incidence of cutaneous melanoma in patients with histologically confirmed dysplastic naevus: A follow-up study in a large UK Healthcare Trust [0.03%]
英国大型医疗保障机构黑素瘤患者的临床病史及组织学确认的非典型痣的发病率:一项随访研究
L McDonald,C Clarke,V ONeill et al.
L McDonald et al.