The effect of biosimilar administration on clinical outcomes in patients with adalimumab-controlled psoriasis [0.03%]
生物类似药在阿达木单抗控制银屑病患者中的临床疗效分析
M Panahi,Y Skelly,R Zaman
M Panahi
Background: Adalimumab is an anti-tumour necrosis factor administered for the management of severe psoriasis. Previously limited to Humira, new biosimilar medications have now emerged including Amgevita. To date, there ha...
An updated report on the incidence and epidemiological trends of keratinocyte cancers in the United Kingdom 2013-2018 [0.03%]
2013-2018年英国角质细胞癌的发病率和流行病学变化的最新研究报告
M Kwiatkowska,S Ahmed,M Ardern-Jones et al.
M Kwiatkowska et al.
Introduction: The most common cancers in the UK are keratinocyte cancers (KCs): the combined term for basal cell carcinomas (BCCs) and cutaneous squamous cell carcinomas (cSCCs). Registration of KC is challenging due to h...
Cutaneous sarcoidosis due to immune-checkpoint inhibition and exacerbated by a novel BRAF dimerization inhibitor [0.03%]
免疫检查点抑制诱导的皮肤病理性淋巴细胞浸润加重与新型BRAF二聚化抑制剂有关
J P Pham,P Star,S Wong et al.
J P Pham et al.
Sarcoidosis is a non-infective granulomatous disorder of unknown aetiology, with cutaneous involvement affecting up to 30% of patients. Drug-induced sarcoidosis has been reported secondary to modern melanoma therapies including immune-check...
Case Reports
Skin health and disease. 2021 Oct 20;1(4):e71. DOI:10.1002/ski2.71 2021
CD8αα+T cells exert a pro-inflammatory role in patients with psoriasis [0.03%]
CD8αα+T细胞在银屑病患者中发挥促炎作用
Y Y Zhang,Y T Lin,L Wang et al.
Y Y Zhang et al.
Background: Psoriasis is a common chronic inflammatory disease caused by excessive activation of CD4+T cells, including Th17, Th1 and Th22. The role of CD8+T cells in psoriasis pathogenesis remains poorly understood. ...
Erythrokeratoderma variabilis (EKV) - First Nepalese case documenting GJB3 mutation [0.03%]
变性红皮病性掌跖角化病（EKV）——首例记录GJB3基因突变的尼泊尔病例报告
M Shah,S Baral,R C Adhikari
M Shah
Erythrokeratoderma Variabilis (EKV) is a rare genodermatosis, characterized by variable erythematous and hyperkeratotic skin lesions. It is most often transmitted in autosomal dominant manner (AD). Casual mutations were found in the GJB3 an...
Clinical characteristics and management of acute generalized exanthematous pustulosis with haemodynamic instability [0.03%]
急性全身性脓疱病合并循环系统不稳定患者的临床特征和治疗措施
M O&#x;Brian,C L Carr,C Thomas et al.
M O&#x;Brian et al.
Background: Acute generalized exanthematous pustulosis (AGEP) is a severe pustular drug eruption with rare reports of haemodynamic instability. Objective:...
Facial discoid dermatosis: A cosmetically disfiguring and challenging condition to treat [0.03%]
面部盘状皮损：一种毁容且难以治疗的疾病
S Rahmatulla,K Batta,F Tatnall et al.
S Rahmatulla et al.
Facial discoid dermatosis (FDD) is a recently described condition comprising discrete facial papulo-squamous lesions. We report three cases that clinically and histologically resemble FDD and demonstrate its resistance to treatment. Awarene...
Case Reports
Skin health and disease. 2021 Jun 24;1(4):e56. DOI:10.1002/ski2.56 2021
Merkel cell carcinoma [0.03%]
Merkel细胞癌
K Mistry,N J Levell,P Craig et al.
K Mistry et al.
Merkel cell carcinoma (MCC) is a rare neuroendocrine carcinoma. The cellular origin of MCC may include Merkel cell precursors. The incidence of MCC has increased significantly however trends may have been confounded by evolving diagnostic c...
Effect of topical treatment with 7.5% urea in Ichthyosis Vulgaris: A randomized, controlled, double blinded, split body study evaluating the effect of urea cream compared to the vehicle (moisturizing) cream [0.03%]
局部外用7.5％尿素治疗寻常鱼鳞病：一项随机对照双盲半脸研究评估尿素乳膏与安慰剂（保湿）乳膏的效果
I L H Dorf,M S Lunen,U Koppelhus
I L H Dorf
Background: Ichthyosis Vulgaris (IV) is a common genetic skin disease, characterized by dry, scaling skin and itch. Urea cream has been a central part of IV treatment for decades, but only few studies have evaluated the e...
Health utilities for non-melanoma skin cancers and pre-cancerous lesions: A systematic review [0.03%]
非黑色素瘤皮肤癌和癌前病变的健康效用：系统评价
C So,A E Cust,L G Gordon et al.
C So et al.
Background: Non-melanoma skin cancers (NMSCs) are common and consume many healthcare resources. A health utility is a single preference-based value for assessing health-related quality of life, which can be used in econom...