A digital therapeutic for management of psychosocial aspects of psoriasis: A pre-post proof of concept study [0.03%]
一种用于银屑病心理社会方面的管理的数字疗法：一种前后期概念验证研究
D G Fortune,V Ravnkilde,S Ryan et al.
D G Fortune et al.
Background: Despite the psychosocial challenges of living with psoriasis many patients may not be able to access appropriate services to manage these challenges. Mobile health interventions may be helpful as a means to su...
Melanogenic effect of dersimelagon (MT-7117), a novel oral melanocortin 1 receptor agonist [0.03%]
新型口服黑素皮质素1受体激动剂德西美拉隆（MT-7117）的黑色素刺激作用
T Suzuki,Y Kawano,A Matsumoto et al.
T Suzuki et al.
Background: The activation of melanocortin 1 receptor (MC1R) on melanocytes stimulates the production of eumelanin. A tridecapeptide α melanocyte-stimulating hormone (αMSH) is known to induce skin pigmentation. ...
A case of anti-laminin gamma-1 (p200) pemphigoid with bullous lesions on the lips, hands and feet showing antibodies to desmoglein 1 [0.03%]
抗层粘连蛋白γ-1（p200）天疱疮伴唇、手和足部水疱的病例，显示抗desmoglein 1抗体阳性
F Kaneko,M Ozasa,A Togashi
F Kaneko
An 87-years-old-man presented with bullous and erosive lesions exclusively on the lips, hands and feet. Histopathological and direct immunofluorescence studies suggested the diagnosis of bullous pemphigoid, but the serum anti-BP180 antibodi...
Case Reports
Skin health and disease. 2022 Feb 11;2(1):e101. DOI:10.1002/ski2.101 2022
Predictive factors for Day 7 positive patch test readings at a secondary referral centre [0.03%]
二级转诊中心阳性贴剂筛查结果的预测因素
R A Tupker,W G C Stapper,J C Kelder
R A Tupker
Background: Based on studies at tertiary centres it is known that patch test reading on Day (D) 7 may show additional positive reactions. Female gender, higher age and allergen groups of topicals and corticosteroids were ...
A Herzum,C Micalizzi,M F Molle et al.
A Herzum et al.
Background: Coronavirus disease 2019 (COVID-19) disease and vaccines have been associated to various skin reactions, which are mostly similar amongst them. New onset of vitiligo and hypopigmentations have been described f...
S J Huang,Y Liu,K Kanada et al.
S J Huang et al.
A preliminary study of peripheral T-cell subsets in porokeratosis patients with MVK or MVD variants [0.03%]
MVK或MVD变异型掌跖角化病患者外周血T细胞亚群初步研究
L Tao,Y K Huang,K X Yan et al.
L Tao et al.
Background: Porokeratosis (PK) is considered a skin-specific autoinflammatory keratinization disease. Intriguingly, four causative genes of PK are in turn arranged in mevalonate pathway, with MVD variants being the common...
L L Yang,B Jiang,S H Chen et al.
L L Yang et al.
Background: Prurigo nodularis (PN) is a highly pruritic, chronic dermatosis and difficult to treat. PN lesions are characterized by existence of many hyperkeratotic, erosive papules and nodules. However, the pathogenesis ...
What can GP data tell us about the treatment of onychomycosis in the UK? [0.03%]
英国通用实践数据能告诉我们关于甲真菌病的哪些治疗信息？
M Sajeed,L Wei,S Murdan
M Sajeed
Background: Treatment of onychomycosis is challenging, and there is much literature on optimal treatment strategies. In contrast, information on how onychomycosis is actually treated in primary care is scarce. Information...
Recalcitrant erythrodermic ichthyosis with atopic dermatitis successfully treated with Dupilumab in combination with Guselkumab [0.03%]
一名难治性红皮病型鱼鳞病伴特应性皮炎患者使用Dupilumab联合Guselkumab治疗后获成功缓解病例报告
M Steinhoff,F Al-Marri,R Al Chalabi et al.
M Steinhoff et al.
Background: Autosomal recessive congenital ichthyosis refers to a group of rare inherited disorders of keratinization and defective epidermal barrier resulting in varying clinical presentations and severities ranging from...
Case Reports
Skin health and disease. 2021 Dec 22;2(1):e87. DOI:10.1002/ski2.87 2021