Nageswary Nadarajah,Cedric Ho Tiu,Shernaz Walton
Nageswary Nadarajah
Background: Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis that may be associated with systemic diseases. Characterizing these associations is clinically relevant for diagnosis, prognosis and management. ...
Spironolactone for the treatment of acne vulgaris affecting female patients aged ≤ 18 years: results from a UK and Irish Survey of healthcare professionals [0.03%]
螺内酯治疗≤18岁的女性寻常痤疮患者:来自英国和爱尔兰医疗保健专业人员调查的结果
Zahra Moledina,Lisa OHiggins,Myranda Attard et al.
Zahra Moledina et al.
A survey of UK and Irish healthcare professionals was distributed via the UK Dermatology Clinical Trials Network, British Society for Paediatric and Adolescent Dermatologists, Irish Association of Dermatologists and other regional groups. T...
A middle-aged man with progressive facial swelling and generalized violaceous plaques [0.03%]
面部进行性肿胀和全身紫红色斑片的中年男性患者
Sirikorn Densrisereekul,Jarukit Tantipisit,Suthep Jerasutus et al.
Sirikorn Densrisereekul et al.
This report describes a patient with AIDS-related angiomatous Kaposi sarcoma (KS) presenting with facial lymphoedema. Angiomatous KS is a rare histological subtype of KS that can mimic benign haemangiomas clinically and histologically. Furt...
Shraddha Uprety,Pratichya Thapa,Prakriti Lamichhane et al.
Shraddha Uprety et al.
Extradigital glomangioma is a rare variant of glomangioma with few cases reported over the extremities, trunk and visceral organs. Patients with extradigital glomangioma lack classic signs and symptoms in comparison with typical glomangioma...
Factors associated with prolonged hospital stay in patients with autoimmune bullous diseases treated at an in-patient dermatology service [0.03%]
与自身免疫性大疱病住院时间延长相关的因素分析
Pedro Juan Saldarriaga-Muñoz,Valentina Rodelo-Sánchez,Isabela Agudelo-Aguilar et al.
Pedro Juan Saldarriaga-Muñoz et al.
Background: Bullous diseases carry a great burden and are often linked to high healthcare costs. Patients with -bullous diseases are more vulnerable to infections and organ damage due to an incompetent skin barrier. ...
Guselkumab treatment of psoriasis results in sustained reduction of systemic inflammatory biomarkers to week 48 in three phase III randomized controlled trials [0.03%]
III期三项随机对照试验中 Guselkumab 治疗银屑病可使系统性炎症生物标志物持续降低至第48周
Niamh Kearney,Miriam Zimmermann,Alianu Akawung et al.
Niamh Kearney et al.
Increased risk of major adverse cardiac events (MACE) may be linked to systemic inflammation for patients with psoriasis. Guselkumab is an effective treatment for psoriasis and psoriatic arthritis that was previously shown to reduce inflamm...
Drug survival of biologic treatments for psoriasis and psoriatic arthritis in Denmark, 2018-23: a nationwide register-based cohort study [0.03%]
丹麦2018-2023年生物制剂治疗银屑病和银屑病关节炎的用药持续情况:一项基于全国登记数据的队列研究
Sejun Kim,Andreas Jensen,Alexander Egeberg et al.
Sejun Kim et al.
Background: Psoriasis is a chronic inflammatory skin condition. It is being increasingly treated with biologic agents targeting specific immune pathways. These treatments target specific immune system pathways involved in...
Is Demodex hiding in lichen planopilaris pathogenesis? The trichoscopy-blind zone [0.03%]
毛囊苔藓样皮炎发病机制中毛囊蠕形螨在作怪?--皮肤镜盲区
Kambiz Kamyab Hesari,Alireza Ghanadan,Vahidehsadat Azhari et al.
Kambiz Kamyab Hesari et al.
The pathogenic role of commensal Demodex mites in lichen planopilaris remains hypothetical. We propose a multifactorial model where mite lipases and antigens disrupt follicular peroxisome proliferator-activated receptor gamma (PPAR-γ) sign...
Healthcare resource use, costs and health-related quality of life in the UK-Irish Atopic eczema Systemic Therapy Register (A-STAR): a pilot study [0.03%]
英国-爱尔兰特应性皮炎系统用药注册登记(A-STAR)的卫生资源利用、成本和生命质量:一项试点研究
Carlos Chivardi,Elizaveta Gribaleva,Bolaji Coker et al.
Carlos Chivardi et al.
Background: Managing patients with moderate-to-severe atopic eczema (AE) is challenging. Novel systemic immunomodulatory therapies are effective but costly, whereas conventional treatments require more intense safety moni...
Bullous pemphigoid in patients who are frail: a case complicated by cerebral nocardiosis and Pneumocystis jirovecii pneumonia [0.03%]
脆弱患者中天疱疮一例并颅内诺卡菌病和卡氏肺孢子虫肺炎
Simone Landini,Alessandro Magnatta,Alberto Corrà et al.
Simone Landini et al.
Bullous pemphigoid (BP) is the most common autoimmune blistering disorder in older patients and is typically managed with long-term immunosuppressive therapy tailored to the patient's comorbidities and overall health. Patients who are frail...