Risk factors for cardiovascular disease mortality in patients with myelodysplastic syndromes: A nationwide, registry-based cohort study [0.03%]
基于登记处的全国性队列研究中肌无力综合症患者心血管疾病死亡的风险因素
Konstantinos Liapis,Georgios Vrachiolias,Vasileios Papadopoulos et al.
Konstantinos Liapis et al.
Cardiovascular disease (CVD) emerges as a major cause of death in patients with myelodysplastic syndrome (MDS), but predictors of fatal CVD and the effect of MDS-specific treatments on CVD mortality remain largely unknown. In an analysis in...
Immune reconstitution following umbilical cord blood transplantation: IRES, a study of UK paediatric patients [0.03%]
来自英国儿科患者的胎盘血干细胞移植后免疫重建研究(IRES)
John Girdlestone,Meera Raymond,Bronwen Shaw et al.
John Girdlestone et al.
To obtain a qualitative as well as quantitative view immune reconstitution following umbilical cord blood (UCB) transplantation of paediatric patients, we utilised a broad panel of flow cytometry markers to monitor the phenotypes of lymphoi...
Combination of cyclophosphamide and cytarabine as induction regimen for newly diagnosed adult acute myeloid leukemia [0.03%]
环磷酰胺联合阿糖胞苷治疗成人新诊断急性髓系白血病诱导缓解方案
Qingguo Liu,Hongye Gao,Junfan Li et al.
Qingguo Liu et al.
Optimizing the induction therapy of acute myeloid leukemia (AML) may improve the remission rate and reduce the risk of relapse, thereby extend survival. Cyclophosphamide (CTX) shows benefit in treating relapsed and refractory AML patients, ...
Social frailty predicts worse outcomes in patients with multiple myeloma: A novelty in an old approach [0.03%]
社会脆弱性预测多发性骨髓瘤患者的预后不良：旧方法中的新特点
Toshiki Terao,Takafumi Tsushima,Daisuke Miura et al.
Toshiki Terao et al.
Social frailty, defined as the loss of social roles and networks in the community, has never been evaluated in patients with multiple myeloma (MM). This study aimed to evaluate the usefulness of social frailty as a predictor of survival in ...
Alcohol and tobacco use and risk of multiple myeloma: A case-control study [0.03%]
饮酒和烟草使用与多发性骨髓瘤风险的关系：一项病例对照研究
Simon Cheah,Julie K Bassett,Fiona J Bruinsma et al.
Simon Cheah et al.
Multiple myeloma (MM) is the second most common hematological cancer and causes significant mortality and morbidity. Knowledge regarding modifiable risk factors for MM remains limited. This analysis of an Australian population-based case-co...
Cholecystectomy in a patient with paroxysmal nocturnal haemoglobinuria undergoing ravulizumab maintenance treatment [0.03%]
用于预防阵发性夜间血红蛋白尿的 Ravulizumab 维持治疗患者的胆囊切除术
Mitsuru Moriyama,Yasuo Aota,Masahiro Okabe et al.
Mitsuru Moriyama et al.
A 47-year-old male with paroxysmal nocturnal haemoglobinuria (PNH) controlled with routine ravulizumab administration suffered a massive haemolytic crisis due to choledocholithiasis. Laparoscopic cholecystectomy was performed 6 weeks after ...
Case Reports
EJHaem. 2021 Nov 9;3(1):203-206. DOI:10.1002/jha2.336 2021
Degradation of red blood cell deformability during cold storage in blood bags [0.03%]
血液保存过程中红细胞变形能力的下降
Emel Islamzada,Kerryn Matthews,Erik S Lamoureux et al.
Emel Islamzada et al.
Red blood cells (RBCs) stored in blood bags develop a storage lesion that include structural, metabolic, and morphologic transformations resulting in a progressive loss of RBC deformability. The speed of RBC deformability loss is donor-depe...
Rare additional chromosomal abnormalities in acute promyelocytic leukaemia resulting in rapidly fatal disease: report of a case [0.03%]
急性早幼粒细胞白血病罕见的额外染色体异常导致病情迅速恶化：一例报告
Ahmed Maseh Haidary,Sarah Noor,Sahar Noor et al.
Ahmed Maseh Haidary et al.
Background: Acute promyelocytic leukaemia results from reciprocal translocation between the long arms of chromosomes 15 and 17. This translocation leads to the formation of chimeric gene, which is both the diagnostic mark...
Case Reports
EJHaem. 2021 Nov 30;3(1):218-222. DOI:10.1002/jha2.349 2021
Phase Ib study of combinations of avadomide (CC-122), CC-223, CC-292, and rituximab in patients with relapsed/refractory diffuse large B-cell lymphoma [0.03%]
评估CC-122、CC-223、CC-292和利妥昔单抗联合用药在复发/难治弥漫大B细胞淋巴瘤患者中Ⅰb期试验
Vincent Ribrag,Julio C Chavez,Carola Boccomini et al.
Vincent Ribrag et al.
There is a need for additional treatment options for patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) who do not benefit from available therapies. We examined combinations of the cereblon E3 ligase modulator (CELMo...
Dyserythropoietic anaemia with an intronic GATA1 splicing mutation in patients suspected to have Diamond-Blackfan anaemia [0.03%]
疑似钻石-黑扇贫血患者的核仁GATA1剪接突变所致的红细胞系发育异常性贫血
Akie Kobayashi,Ryusei Ohtaka,Tsutomu Toki et al.
Akie Kobayashi et al.
Diamond-Blackfan anaemia (DBA) shares clinical features with two recently reported sporadic cases of dyserythropoietic anaemia with a cryptic GATA1 splicing mutation (c.871-24 C>T). We hypothesized that some patients clinically diagnosed wi...