PD1 expression on bone marrow T-cells in newly diagnosed Egyptian AML patients: Correlation with hematological parameters, aberrant antigens expression, and response to induction therapy [0.03%]
初治埃及急性髓系白血病患者骨髓T细胞PD1表达与其血液学参数、异常抗原表达及诱导治疗反应的相关性研究
Noha Bassiouny,Nour El-Hoda,Ibtesam M Khalifa et al.
Noha Bassiouny et al.
Background: Programed cell death protein 1 (PD-1) is a key mediator for the development of T cell exhaustion that develops in response to persistent antigen stimulation. ...
Etoposide-based treatment of adult HLH is associated with high biochemical response but poor survival outcomes [0.03%]
依托泊苷治疗成人HLH疗效不佳
Matthew C Nicholson,Leonie Naeije,Anna R Hayden et al.
Matthew C Nicholson et al.
Etoposide-based treatment is the standard of care for adult HLH in many centers, yet there remains a paucity of data regarding treatment outcomes. We conducted a retrospective study of 23 adults treated with etoposide-based therapy compared...
Therapy related acute myeloid leukemia with blast cannibalism and cytophagocytosis [0.03%]
治疗相关急性髓系白血病伴原始细胞吞噬现象
Habib Moshref Razavi,Thomas Covello
Habib Moshref Razavi
The case of an 83-year old male patient is described. He presented to our hospital with a 2 week history of intermittent syncope and was diagnosed with atrial fibrillation. His CBC showed bicytopenia with anemia and neutropenia in context o...
Low serum albumin is an independent risk factor in elderly patients with aggressive B-cell lymphoma: Results from prospective trials of the German High-Grade Non-Hodgkin's Lymphoma Study Group [0.03%]
老年侵袭性B细胞淋巴瘤患者低血清白蛋白水平是独立危险因素：德国高级别非霍奇金淋巴瘤研究组前瞻性试验结果分析
Karin Hohloch,Marita Ziepert,Lorenz Truemper et al.
Karin Hohloch et al.
Serum albumin a well-known risk factor predicting outcome in many solid tumors. We explore the role of low serum albumin (≤3.5 g/dL) as an independent risk factor in elderly patients with aggressive B-cell lymphoma. Outcome of 429 patients...
Quality of life and socioeconomic indicators associated with survival of myeloid leukemias in Canada [0.03%]
加拿大与髓系白血病生存率相关的社会经济指标和生活质量
Sonya Cressman,Donna E Hogge,Mark D Minden et al.
Sonya Cressman et al.
Understanding how patient-reported quality of life (QoL) and socioeconomic status (SES) relate to survival of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) may improve prognostic information sharing. This study explores as...
Bacillus Calmette-Guérin (BCG)-associated hemophagocytic lymphohistiocytosis in the setting of IFN-γR1 deficiency: A diagnostic dilemma [0.03%]
干扰素-γ受体1缺乏并发结核菌苗（BCG）相关噬血细胞淋巴组织细胞增生症的诊断难题
Anahita Razaghian,Leila Parvaneh,Mona Delkhah et al.
Anahita Razaghian et al.
Hemophagocytic lymphohistiocytosis (HLH) disease is a severe immune dysregulation caused by mutations in genes required for lymphocyte cytotoxicity function. However, HLH-like syndrome may develop secondary to infections, malignancy, and au...
Case Reports
EJHaem. 2020 Apr 28;1(1):334-337. DOI:10.1002/jha2.5 2020
Pegylated interferon 2a and ruxolitinib induce a high rate of oral complications among patients with myeloproliferative neoplasms [0.03%]
聚乙二醇干扰素2a和鲁索利替尼会导致我的 proliferative肿瘤患者出现较高的口腔并发症率
Marie Orliaguet,Sylvie Boisramé,Jean-Richard Eveillard et al.
Marie Orliaguet et al.
A retrospective analysis of venous thromboembolism trends in chemotherapy-induced anemia: Red blood cell transfusion versus erythrocyte stimulating agent administration [0.03%]
化疗诱导的贫血患者输血与促红细胞生成素使用趋势的回顾性分析
Emily J Bryer,Michael J Kallan,Ting-Shan Chiu et al.
Emily J Bryer et al.
Background: Patients receiving a variety of chemotherapy regimens often develop chemotherapy-induced anemia (CIA), which contributes to poor outcomes including increased mortality. Prompt and effective treatment of CIA is...
Bone marrow infiltration pattern in patients with intravascular large B-cell lymphoma diagnosed by random skin biopsy [0.03%]
随机皮肤活检诊断的血管内大B细胞淋巴瘤患者的骨髓浸润模式
Kosei Matsue,Yoshiaki Abe,Kentaro Narita et al.
Kosei Matsue et al.
We retrospectively analyzed bone marrow (BM) infiltration pattern in consecutive 30 intravascular large B-cell lymphoma (IVLBCL) patients diagnosed by random skin biopsy (RSB). BM infiltration of lymphoma was observed in 18 patients (60.0%)...
Plasma thymus and activation-regulated chemokine (TARC) as diagnostic marker in pediatric Hodgkin lymphoma [0.03%]
血浆胸腺活化调节化学因子(TARC)在儿童霍奇金淋巴瘤中的诊断价值
Eline A M Zijtregtop,Friederike Meyer-Wentrup,Wai-Chu Wong et al.
Eline A M Zijtregtop et al.
Pediatric classical Hodgkin's lymphoma (cHL) is characterized by Hodgkin Reed-Sternberg cells located in an inflammatory microenvironment. Blood biomarkers result from active crosstalk between these cells. One promising biomarker in adult c...