iRGD-targeted Physalis Mottle Virus-like Nanoparticles for Targeted Cancer Delivery [0.03%]
iRGD修饰的茄摩洛病毒样纳米颗粒用于靶向癌症给药
Krister J Barkovich,Zhongchao Zhao,Nicole F Steinmetz
Krister J Barkovich
Nanomedicine provides a promising platform for the molecular treatment of disease. An ongoing challenge in nanomedicine is the targeted delivery of intravenously administered nanoparticles to particular tissues, which is of special interest...
Spatially Guided Construction of Multilayered Epidermal Models Recapturing Structural Hierarchy and Cell-Cell Junctions [0.03%]
空间引导构建多层表皮模型以重现结构层次和细胞-细胞连接
Haiwei Zhai,Xiaowei Jin,Grayson Minnick et al.
Haiwei Zhai et al.
A current challenge in three-dimensional (3D) bioprinting of skin equivalents is to recreate the distinct basal and suprabasal layers and to promote their direct interactions. Such a structural arrangement is essential to establish 3D strat...
Oridonin Inhibits SARS-CoV-2 by Targeting Its 3C-Like Protease [0.03%]
Oroidonin通过靶向其3CL蛋白酶抑制SARS-CoV-2
Baisen Zhong,Weiyu Peng,Shan Du et al.
Baisen Zhong et al.
Oridonin Inhibits SARS-CoV-2 Oridonin, a natural product extracted from Rabdosia rubescens, possesses a wide range of pharmacological properties, including anti-inflammatory, anti-cancer, anti-microbial, neuroprotection, immunoregulation, e...
Rapid Antigen Diagnostics as Frontline Testing in the COVID-19 Pandemic [0.03%]
新冠肺炎大流行期间快速抗原检测试剂作为初步筛查工具的有效性分析
Jiang Xu,Liam Kerr,Yue Jiang et al.
Jiang Xu et al.
The ongoing global COVID-19 pandemic, caused by the SARS-CoV-2 virus, has resulted in significant loss of life since December 2019. Timely and precise virus detection has been proven as an effective solution to reduce the spread of the viru...
Oridonin Inhibits SARS-CoV-2 by Targeting Its 3C-Like Protease [0.03%]
Orodonin通过靶向其3CL蛋白酶抑制SARS-CoV-2
Baisen Zhong,Weiyu Peng,Shan Du et al.
Baisen Zhong et al.
The current COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an enormous threat to public health. The SARS-CoV-2 3C-like protease (3CLpro), which is critical for viral replication and transcripti...
Computational Method-Based Optimization of Carbon Nanotube Thin-Film Immunosensor for Rapid Detection of SARS-CoV-2 Virus [0.03%]
基于计算方法优化碳纳米管薄层免疫传感器以快速检测SARS-COV-2病毒
Su Yeong Kim,Jeong-Chan Lee,Giwan Seo et al.
Su Yeong Kim et al.
The recent global spread of COVID-19 stresses the importance of developing diagnostic testing that is rapid and does not require specialized laboratories. In this regard, nanomaterial thin-film-based immunosensors fabricated via solution pr...
Microscale Photopatterning of Through-thickness Modulus in a Monolithic and Functionally Graded 3D Printed Part [0.03%]
用于单体和功能梯度3D打印部件的厚度模量微尺度光图案化技术
Asais Camila Uzcategui,Callie I Higgins,John E Hergert et al.
Asais Camila Uzcategui et al.
3D printing is transforming traditional processing methods for applications ranging from tissue engineering to optics. To fulfill its maximum potential, 3D printing requires a robust technique for producing structures with precise three-dim...