Participant-Reported Preference for Pembrolizumab Administered Subcutaneously or Intravenously: A Randomized, Open-Label, Phase II Study [0.03%]
帕博利尤单抗皮下给药或静脉给药患者倾向的随机、开放标签II期研究
Ignacio A Casarini,Dariusz M Kowalski,Christian Caglevic et al.
Ignacio A Casarini et al.
Purpose: Pembrolizumab with berahyaluronidase alfa, a human hyaluronidase variant, is for subcutaneous (SC) injection. The phase II, open-label, crossover study 3475A-F11 (ClinicalTrials.gov identifier: NCT06099782) asses...
John M Burke
John M Burke
Importance of Physician Advocacy in the Fight to Protect Local Cancer Care [0.03%]
医师倡导在保护本地癌症治疗中的重要性
Leslie T Busby,Rupesh J Parikh
Leslie T Busby
GLP-1 Agonists Are Associated With a Significant Reduction in Breast Cancer Incidence in Women [0.03%]
GLP-1受体激动剂与女性乳腺癌发病率显著降低有关
Elizabeth S McDonald,Laura B Gillis,Peter Gabriel et al.
Elizabeth S McDonald et al.
Purpose: Excess weight is a key modifiable risk factor for breast cancer. Glucagon-like peptide-1 receptor agonists (GLP-1) promote weight loss and improve metabolic health, but their effect on breast cancer risk remains ...
Standard Versus Reduced Sotorasib Dosing in KRAS G12C-Mutated Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis-Have We Answered the Dosing Question? [0.03%]
索托雷塞标准剂量与减量在KRAS G12C突变型非小细胞肺癌中的系统评价和meta分析-我们已经回答了关于给药方案的问题了吗？
Wint Yan Aung,Melissa Neumann,Kevin Y Wang et al.
Wint Yan Aung et al.
Purpose: Sotorasib represents an early example in which the US Food and Drug Administration (FDA) requested formal dose optimization under Project Optimus. Although 960 mg remains the labeled dose, tolerability is often c...
Expert Validation of an Artificial Intelligence-Enabled Trial Matching Solution Using Real-World Data From Patients With Cancer [0.03%]
基于真实世界数据的癌症患者人工智能辅助临床试验匹配解决方案的专家验证研究
Jai N Patel,M Cyrus Maher,Victoria Morris et al.
Jai N Patel et al.
Purpose: To validate the performance of an AI system (TRIAGE) for cancer trial eligibility screening using real-world longitudinal electronic health records (EHRs), full versioned trial protocols, and expert clinical rese...
Impact of Dedicated Care Coordination on Access to Multidimensional Support Services in Young-Onset Colorectal Cancer: A Pragmatic Trial [0.03%]
专门护理协调对青年人结直肠癌多维度支持性服务利用的影响：实用试验研究
Jeongyoon Moon,Elaine Maghanoy,Victoria S Higbie et al.
Jeongyoon Moon et al.
Purpose: The incidence of young-onset colorectal cancer is increasing, and affected patients experience distinct challenges. Patients with young-onset colorectal cancer may benefit from a dedicated care coordinator that s...
Artificial Intelligence Among U.S. Hematology Oncology Fellows: A Multicenter Survey of Education, Attitudes, and Clinical Use [0.03%]
美国血液肿瘤学研究生的人工智能教育、态度和临床使用的多中心调查研究
Evan Garrad,Inas Abuali,Jess DeLaune et al.
Evan Garrad et al.
Purpose: A prior national survey of U.S. hematology/oncology (H/O) fellowship curricula demonstrated substantial heterogeneity and limited protected didactic time. Since then, artificial intelligence (AI), including large...
Optimizing Cancer Care Delivery Through High-Functioning Teams: Results of Implementing the 4R Oncology Model in Lung and Breast Cancers [0.03%]
基于4R肿瘤模型的高效率团队在肺癌和乳腺癌诊疗中的实施及优化效果研究
Julia R Trosman,Christine B Weldon,Elizabeth Linehan et al.
Julia R Trosman et al.
Purpose: Cancer care is highly interdependent, but optimal timing and sequencing is challenging. Teamwork is a promising approach to optimize care timing and sequencing. We previously showed that the 4R Oncology model fos...