Never Stop the Pressure: Maintaining Angiogenesis Inhibition Beyond Progression in Metastatic Renal Cell Carcinoma [0.03%]
维持肾细胞癌血管生成抑制:永不言弃——转移性肾细胞癌进展后的治疗策略
Alessandro Rametta,Amedeo Nuzzo,Elena Verzoni et al.
Alessandro Rametta et al.
Toxicity of Capecitabine and Oxaliplatin as Adjuvant Therapy for Stage III Colorectal Cancer Patients With Diverting Stoma [0.03%]
卡培他滨联合奥沙利铂在造瘘III期结直肠癌患者术后毒性反应的Ⅱ期研究
Andrea Marques,Julie Henriques,Dewi Vernerey et al.
Andrea Marques et al.
Purpose: Standard adjuvant treatment for stage III colorectal cancer (CRC) combines intravenous oxaliplatin with a fluoropyrimidine, either with intravenous 5-fluorouracil with folinic acid oxaliplatin, capecitabine (CAPO...
Cost-Effectiveness of Circulating Tumor DNA-Guided Adjuvant Atezolizumab in Muscle-Invasive Bladder Cancer Based on IMvigor011 Trial [0.03%]
基于IMvigor011试验的肌侵袭性膀胱癌循环肿瘤DNA指导下的阿特珠单抗辅助治疗的成本效益分析
Zihan Xue,Yunkai Qie,Shan Liang et al.
Zihan Xue et al.
Purpose: The optimal adjuvant treatment approach for muscle-invasive bladder cancer (MIBC) remains unsettled. The IMvigor011 trial demonstrated that circulating tumor DNA (ctDNA)-guided adjuvant atezolizumab improves outc...
Burnout in Oncology Clinical Research Coordinators: Underlying Factors and Role of Empathy as a Moderator [0.03%]
肿瘤临床研究协调员的职业耗竭:潜在影响因素及共情的调节作用
Aviv Kidron,Ron Ben-Dor,Dan Otap et al.
Aviv Kidron et al.
Purpose: Clinical research coordinators (CRCs) are essential for the conduct of oncology clinical trials. They work under demanding conditions and face unique emotional stressors that may lead to burnout and high turnover...
Acute Care Events During Systemic Cancer Treatment: Moving From Risk Prediction to Clinical Decision Support Using a Two-Model Approach [0.03%]
系统性癌症治疗期间急性事件的发生:从风险预测到临床决策支持的双模型方法
Jacob Newton Stein,Soroush Fariman,Yishu Zhang et al.
Jacob Newton Stein et al.
Purpose: Acute care events (ACEs, emergency department visits and hospitalizations) are burdensome among patients with cancer-many are preventable. Prognostic risk models have not been consistently deployed as a preventiv...
Comparable Effectiveness of Weight-Based and Fixed-Dose Pembrolizumab in Non-Small Cell Lung Cancer: Insights From a National Real-World Cohort [0.03%]
基于体重和固定剂量派姆单抗治疗非小细胞肺癌的疗效差异:来自全国真实世界队列的见解
Eliya Shachar,Uriel Katz,Shir Barilier et al.
Eliya Shachar et al.
Purpose: Pembrolizumab, a PD-1 immune checkpoint inhibitor (ICI), is a standard first-line treatment for advanced non-small cell lung cancer (NSCLC). Although fixed-dose pembrolizumab (200 mg once every 3 weeks) is widely...
Perceptions of Prognosis and Hope Among Patients With Advanced Cancer at the Time of Enrollment in an Early-Phase Clinical Trial [0.03%]
晚期癌症患者在早期临床试验入组时对预后和希望的看法
Mary C Boulanger,Debra M Lundquist,Andrea Pelletier et al.
Mary C Boulanger et al.
Purpose: Patients overestimate their likelihood of benefit from early phase clinical trials (EPCT). Concerns about taking away hope from patients represent a purported barrier to prognostic discussions. In this study, we ...
Barriers, Facilitators, and Attitudes Toward Telemedicine Adoption in Oncology: A Qualitative Study of Patients From Low-Broadband Areas [0.03%]
一项定性研究:低宽带地区肿瘤学患者对远程医学使用的障碍、促进因素及态度
Pravesh Sharma,Celia C Kamath,Sarah E Jeno et al.
Pravesh Sharma et al.
Purpose: Limited access to high-speed internet (broadband [BB]) may pose challenges to video telehealth visit (VTV) utilization. This study explored barriers, facilitators, and attitudes toward VTV adoption in patients wi...
Economic Evaluation of GARDE: A Digital Health Platform for Population-Level Hereditary Cancer Risk Assessment [0.03%]
GARDE的经济评估:一种针对人群遗传性癌症风险评估的数字健康平台
Muhammad Danyal Ahsan,Kimberly A Kaphingst,Wendy K Kohlmann et al.
Muhammad Danyal Ahsan et al.
Purpose: Over 90% of people with hereditary cancer syndromes in the United States remain unidentified. The Genetic Cancer Risk Detector (GARDE) is an open-source, electronic health record (EHR)-integrated, digital health ...
Economics of Translating Research Into Practice: The Case of Exercise to Prevent Cancer Recurrence [0.03%]
研究转化为实践的经济性——以运动预防癌症复发为例
Allan S Detsky,Kerry S Courneya,Christopher M Booth et al.
Allan S Detsky et al.