Repurposing Renin-Angiotensin System Inhibitors in Colon Cancer: Signal, Plausibility, and the Need for Prospective Validation [0.03%]
血管紧张素系统抑制剂在结直肠癌中再利用：信号，合理性及前瞻性验证的需求
Muhammet Ozer,Timothy J Brown
Muhammet Ozer
Efficacy of Renin-Angiotensin System Inhibitors in Long-Term Oncologic Outcomes of Patients With Stage II/III Colon Cancer and Hypertension: A Target Trial Emulation [0.03%]
血管紧张素抑制剂对II/III期结肠癌合并高血压患者长期预后的影响：靶向试验模拟研究
Kaiwen Chen,Donghao Xu,Zhiyuan Zhang et al.
Kaiwen Chen et al.
Purpose: Renin-angiotensin system inhibitors (RASIs) have been reported to exert anticancer effects. However, there is still a lack of persuasive evidence for their role in improving postoperative long-term oncologic outc...
Guidelines Can Be Lifesaving: The Vermont Model of Thromboprophylaxis Implementation [0.03%]
指南可以拯救生命：弗蒙特实施血栓预防的模式
Dana Angelini,Alok A Khorana
Dana Angelini
Real-World Treatment Patterns and Outcomes Among Patients With Newly Diagnosed AML in the United States [0.03%]
美国新诊断急性髓系白血病患者的真实世界治疗模式和结局研究
Elizabeth Dianne Pulte,Laura L Fernandes,Kelly Norsworthy et al.
Elizabeth Dianne Pulte et al.
Purpose: The US Food and Drug Administration has approved multiple new treatments for AML since 2017 based on demonstrated efficacy and safety in clinical trials. However, the uptake of new treatments and effectiveness in...
Trends in Long-Term Survival Among Patients With De Novo Metastatic Cancer [0.03%]
初始即出现转移的癌症患者的长期生存率变化趋势
Saad Badat,Braden Lau,Fang Wang et al.
Saad Badat et al.
Purpose: Although outcomes for nonmetastatic cancers have improved since the 1970s, it remains uncertain whether long-term survival has improved among patients presenting with de novo metastatic disease, defined as cancer...
Association Between Antibiotic Therapy and Treatment Effectiveness in Patients With Renal Cell Carcinoma Receiving Immune Checkpoint Inhibitors or Tyrosine Kinase Inhibitors [0.03%]
抗生素治疗与肾细胞癌免疫检查点抑制剂或酪氨酸激酶抑制剂疗效之间的联系
Avery E Braun,Hamed Hesami,Mengying Deng et al.
Avery E Braun et al.
Purpose: It has been theorized that antibiotic therapy (ABT) affects response to immune checkpoint inhibition (ICI) by inducing dysbiosis of the gut microbiome (GM). To investigate the association between ABT and real-wor...
Cascade Genetic Testing Among Relatives at Risk for Lynch Syndrome: A Systematic Review and Meta-Analysis [0.03%]
利氏综合症高风险家庭成员中的级联基因检测：系统回顾和 meta 分析
Isabelle R Chandler,Muhammad Danyal Ahsan,Nicole M Frontera et al.
Isabelle R Chandler et al.
Purpose: This is a systematic review and meta-analysis to evaluate the uptake of cascade genetic counseling and testing within families with Lynch syndrome. Our goal was to provide a more current estimate of testing rates...
Parental Knowledge and Decisional Satisfaction Across Genomic Sequencing Consent Processes in Pediatric Cancer [0.03%]
儿童癌症基因组测序知情同意过程中的父母知识和决策满意度
Meaghann S Weaver,Liza-Marie Johnson,Katianne M Howard Sharp et al.
Meaghann S Weaver et al.
Purpose: To determine whether transitioning from a two-visit consent process led by an expert consenter to a decentralized model of consenting using an educational video and a clinical care provider translated into sustai...
Engendering Reproductive Health Within Oncologic Survivorship Trial, ECOG-ACRIN E1Q11 [0.03%]
在肿瘤学生存试验中培养生殖健康，ECOG-ACRIN E1Q11试验
Ashlesha A Patel,Ju-Whei Lee,Howard A Zaren et al.
Ashlesha A Patel et al.
Purpose: For the 10% of women diagnosed with cancer within reproductive age, reproductive health is a critical component of oncologic survivorship. Variable attention to guidelines pertaining to oncocontraception and onco...
Chemotherapy Declination Among Patients With Early-Stage Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer and High Oncotype DX Recurrence Scores [0.03%]
早期激素受体阳性/人类表皮生长因子受体阴性乳腺癌和高ONCOTYPE DX复发评分患者的化疗拒绝率
Inimfon Jackson,Xiudong Lei,Marija Sullivan et al.
Inimfon Jackson et al.
Purpose: Although the 21-gene Oncotype DX assay predicts chemotherapy (CT) benefit in hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer (BC), some patients decline CT d...