Case Report: Scleral hyperpigmentation associated with oral hydroxychloroquine use [0.03%]
个例报告：口服羟氯喹相关的角膜色素沉着症
Caroline Maretz,Felix Omoruyi,Rachel A F Wozniak
Caroline Maretz
Hydroxychloroquine (HCQ) is a commonly used medication for its immunosuppressive and dermatologic effects. It has known ocular side effects, which include retinopathy, corneal deposits, and choroidal thinning. Herein, we report the first kn...
Kalpana Rajanala,Farokh Dotiwala,Arun Upadhyay
Kalpana Rajanala
Geographic atrophy (GA) is an advanced stage of age-related macular degeneration (AMD) that leads to gradual and permanent vision loss. GA is characterized by the loss of photoreceptor cells and retinal pigment epithelium (RPE), leading to ...
Orbital fractures and concurrent ocular injury in a New Zealand tertiary centre [0.03%]
新西兰三级医疗中心的眶骨骨折伴发眼部损伤
Nicholas J Theis,Pritesh Narsinh,Samuel Newlands et al.
Nicholas J Theis et al.
Background: Orbital fractures are a common presentation to acute care and carry an associated risk of ocular injury, however, previous research has not investigated injury rates by fracture category. These patients are fr...
Super-resolution STED imaging in the inner and outer whole-mount mouse retina [0.03%]
用于完整小鼠内、外视网膜的超分辨率STED成像技术
Leon Kremers,Kseniia Sarieva,Felix Hoffmann et al.
Leon Kremers et al.
Since its invention, super-resolution microscopy has become a popular tool for advanced imaging of biological structures, allowing visualisation of subcellular structures at a spatial scale below the diffraction limit. Thus, it is not surpr...
Optic disc edema during strict 6° head-down tilt bed rest is related to one-carbon metabolism pathway genetics and optic cup volume [0.03%]
严格的6°头低位卧床期间视盘水肿与一碳代谢通路遗传学和视杯容积有关
Sara R Zwart,Brandon R Macias,Steven S Laurie et al.
Sara R Zwart et al.
Some astronauts on International Space Station missions experience neuroophthalmological pathologies as part of spaceflight associated neuro-ocular syndrome (SANS). Strict head-down tilt bed rest (HDTBR) is a spaceflight analog that replica...
Jin Zhao,Hye Jin Kim,Diego Montenegro et al.
Jin Zhao et al.
Aim: Iron dysregulation in conjunction with other disease processes may exacerbate retinal degeneration. We employed models of iron overload and iron chelation to explore the interactions between iron-catalyzed oxidation ...
Signaling - transcription interactions in mouse retinal ganglion cells early axon pathfinding -a literature review [0.03%]
小鼠视网膜节细胞早期轴突导向信号转导-转录互作机制文献回顾
Raluca Paşcalău,Tudor Constantin Badea
Raluca Paşcalău
Sending an axon out of the eye and into the target brain nuclei is the defining feature of retinal ganglion cells (RGCs). The literature on RGC axon pathfinding is vast, but it focuses mostly on decision making events such as midline crossi...
Long-term follow-up after treatment of tubercular uveitis: case series and review of the literature [0.03%]
结核性葡萄膜炎治疗的长期随访：病例系列和文献复习
Ikhwanuliman Putera,Paul L A van Daele,Josianne C E M Ten Berge et al.
Ikhwanuliman Putera et al.
Introduction: There is a scarcity of long-term follow-up data and management strategies for recurrent uveitis in tubercular uveitis (TBU), especially in cases extending beyond 10 years after the completion of initial anti...
Unlocking the role of lactate: metabolic pathways, signaling, and gene regulation in postmitotic retinal cells [0.03%]
解开乳酸的作用：代谢途径、信号传导和基因调控在非分裂视网膜细胞中的作用
Raju V S Rajala,Ammaji Rajala
Raju V S Rajala
The Warburg effect, which was first described a century ago, asserts that mitotic tumor cells generate higher quantities of lactate. Intriguingly, even in typical physiological circumstances, postmitotic retinal photoreceptor cells also pro...
Tal Yahalomi,Omar Elhaddad,Venkata Avadhanam et al.
Tal Yahalomi et al.
Purpose: To assess the risk for uveitis, pseudophakic cystoid macular edema (PCME), and posterior capsular opacification (PCO) associated with the use of pupil expansion devices in cataract surgery. ...