High-throughput ultrastructural analysis of macular telangiectasia type 2 [0.03%]
高通量分析黄斑微血管异常二期的超微结构
Charles L Zucker,Paul S Bernstein,Richard L Schalek et al.
Charles L Zucker et al.
Introduction: Macular Telangiectasia type 2 (MacTel), is an uncommon form of late-onset, slowly-progressive macular degeneration. Associated with regional Müller glial cell loss in the retina and the amino acid serine sy...
Oculometric biomarkers of visuomotor deficits in clinically asymptomatic patients with systemic lupus erythematosus undergoing long-term hydroxychloroquine treatment [0.03%]
长期使用羟氯喹的系统性红斑狼疮无临床症状患者的视觉运动障碍的眼动生物标志物
Andrew R Berneshawi,Kimia Seyedmadani,Rahul Goel et al.
Andrew R Berneshawi et al.
Introduction: This study examines a set of oculomotor measurements, or "oculometric" biomarkers, as potential early indicators of visual and visuomotor deficits due to retinal toxicity in asymptomatic Systemic Lupus Eryth...
The significance of growth shells in development of symmetry, transparency, and refraction of the human lens [0.03%]
人眼晶状体对称性、透明性和折射率形成的细胞机制研究
Teri M Greiling,Judy M Clark,John I Clark
Teri M Greiling
Human visual function depends on the biological lens, a biconvex optical element formed by coordinated, synchronous generation of growth shells produced from ordered cells at the lens equator, the distal edge of the epithelium. Growth shell...
Sai Kocherlakota,James B Hurley,Daisy Y Shu
Sai Kocherlakota
Retinal vascular reactivity in carriers of X-linked inherited retinal disease - a study using optical coherence tomography angiography [0.03%]
X连锁遗传性视网膜疾病的携带者的视网膜血管反应性研究——光学相干断层扫描血管成像的研究
Sena Ayse Gocuk,Xavier Hadoux,Charmaine Catipon et al.
Sena Ayse Gocuk et al.
Purpose: Female carriers of X-linked inherited retinal diseases (IRDs) can show highly variable phenotypes and disease progression. Vascular reactivity, a potential disease biomarker, has not been investigated in female I...
Anna M Roszkowska,Rosaria Spinella,Alessandro Calderone et al.
Anna M Roszkowska et al.
Neurotrophic keratitis or keratopathy (NK) is a degenerative corneal disease induced by impairment of the trigeminal nerve function. This condition may lead to persistent epithelial defects, corneal ulceration, and perforation. The diagnosi...
Updates on protein-prenylation and associated inherited retinopathies [0.03%]
蛋白质棕榈酰化研究进展及其相关遗传性视网膜病
Sudhat Ashok,Sriganesh Ramachandra Rao
Sudhat Ashok
Membrane-anchored proteins play critical roles in cell signaling, cellular architecture, and membrane biology. Hydrophilic proteins are post-translationally modified by a diverse range of lipid molecules such as phospholipids, glycosylphosp...
High salt diet alleviates disease severity in native experimental autoimmune uveitis [0.03%]
高盐饮食可缓解自发性实验自身免疫性葡萄膜炎的严重程度
Naomi Derluyn,Vincent Foucart,Marko Verce et al.
Naomi Derluyn et al.
Background: Recent studies reported a link between high salt diet (HSD) and clinical exacerbation in mouse models of autoimmune diseases, mainly through the induction of pathogenic Th17 cells and/or HSD-induced dysbiosis....
Vernal keratoconjunctivitis in adults: a narrative review of prevalence, pathogenesis, and management [0.03%]
成人春季角结膜炎:患病率、发病机制及治疗的叙述性回顾
Antonio Di Zazzo,Angela Y Zhu,Ken Nischal et al.
Antonio Di Zazzo et al.
Vernal keratoconjunctivitis (VKC) is a chronic, progressive, allergic ocular surface disorder that can lead to sight-threatening complications. VKC occurs primarily in children and generally resolves about the time of puberty; however, case...
Improved MRI methods to quantify retinal and choroidal blood flow applied to a model of glaucoma [0.03%]
改进的MRI方法量化视网膜和脉络膜血流并将其应用于青光眼模型
Zhao Jiang,Diane Chernoff,Andre Galenchik-Chan et al.
Zhao Jiang et al.
Purpose: Blood flow (BF) of the retinal and choroidal vasculatures can be quantitatively imaged using MRI. This study sought to improve methods of data acquisition and analysis for MRI of layer-specific retinal and choroi...