Pairing cellular and synaptic dynamics into building blocks of rhythmic neural circuits. A tutorial [0.03%]
结合单元和突触动力学以构建节律性神经回路的基本模块。教程式综述
James Scully,Jassem Bourahmah,David Bloom et al.
James Scully et al.
In this study we focus on two subnetworks common in the circuitry of swim central pattern generators (CPGs) in the sea slugs, Melibe leonina and Dendronotus iris and show that they are independently capable of stably producing emergent netw...
Network approach reveals preferential T-cell and macrophage association with α-linked β-cells in early stage of insulitis in NOD mice [0.03%]
网络分析揭示了T细胞和巨噬细胞在NOD小鼠胰岛炎早期阶段与α-连接的β-细胞的相互作用优先性
Nirmala V Balasenthilkumaran,Jennifer C Whitesell,Laura Pyle et al.
Nirmala V Balasenthilkumaran et al.
One of the challenges in studying islet inflammation-insulitis-is that it is a transient phenomenon. Traditional reporting of the insulitis progression is based on cumulative, donor-averaged values of leucocyte density in the vicinity of pa...
Resilience of the slow component in timescale-separated synchronized oscillators [0.03%]
时间尺度分离同步振子中的慢分量的鲁棒性
Melvyn Tyloo
Melvyn Tyloo
Physiological networks are usually made of a large number of biological oscillators evolving on a multitude of different timescales. Phase oscillators are particularly useful in the modelling of the synchronization dynamics of such systems....
Information theory reveals physiological manifestations of COVID-19 that correlate with symptom density of illness [0.03%]
信息理论揭示了COVID-19的生理表现与疾病症状密度的相关性
Jacob M Ryan,Shreenithi Navaneethan,Natalie Damaso et al.
Jacob M Ryan et al.
Algorithms for the detection of COVID-19 illness from wearable sensor devices tend to implicitly treat the disease as causing a stereotyped (and therefore recognizable) deviation from healthy physiology. In contrast, a substantial diversity...
Thomas Erneux
Thomas Erneux
In this paper, we analyze the strong feedback limit of two negative feedback schemes which have proven to be efficient for many biological processes (protein synthesis, immune responses, breathing disorders). In this limit, the nonlinear de...
Dynamics of a network mediated by IL-36 and involved in the pathogenesis of psoriasis [0.03%]
由IL-36介导的网络在银屑病发病机制中的动态变化
Sneha Pandey,Syona Tiwari,Sulagna Basu et al.
Sneha Pandey et al.
The pathogenesis of the inflammatory, chronic, and common skin disease psoriasis involves immune cells, skin cells (keratinocytes), and the cytokines they secrete. Hyperproliferation and abnormal differentiation of keratinocytes are hallmar...
Coordinated reset stimulation of plastic neural networks with spatially dependent synaptic connections [0.03%]
具有空间依赖突触连接的可塑性神经网络的协同复位刺激
Justus A Kromer,Peter A Tass
Justus A Kromer
Background: Abnormal neuronal synchrony is associated with several neurological disorders, including Parkinson's disease (PD), essential tremor, dystonia, and epilepsy. Coordinated reset (CR) stimulation was developed com...
Cristina Masoller,Klaus Lehnertz,Marc Goodfellow et al.
Cristina Masoller et al.
Elucidating the interaction between stretch and stiffness using an agent-based spring network model of progressive pulmonary fibrosis [0.03%]
利用基于代理的弹簧网络模型阐明拉伸与刚度之间的相互作用以解释进行性肺纤维化现象
Joseph K Hall,Jason H T Bates,Ramaswamy Krishnan et al.
Joseph K Hall et al.
Pulmonary fibrosis is a deadly disease that involves the dysregulation of fibroblasts and myofibroblasts, which are mechanosensitive. Previous computational models have succeeded in modeling stiffness-mediated fibroblasts behaviors; however...
Testing dynamic correlations and nonlinearity in bivariate time series through information measures and surrogate data analysis [0.03%]
基于信息度量和混沌伪数据的双时间序列动力相关性及非线性的检测
Helder Pinto,Ivan Lazic,Yuri Antonacci et al.
Helder Pinto et al.
The increasing availability of time series data depicting the evolution of physical system properties has prompted the development of methods focused on extracting insights into the system behavior over time, discerning whether it stems fro...