Recent clinical advances in fibroblast activation protein targeted radioligand therapy for solid tumors [0.03%]
近年来针对实体瘤成纤维细胞活化蛋白的放射配体治疗临床进展
Xiaolong Wu,Yu Wang,Yingchun Li et al.
Xiaolong Wu et al.
Fibroblast activation protein (FAP) is a type II transmembrane serine protease predominantly expressed by cancer-associated fibroblasts (CAFs) in more than 90% of epithelial malignancies. The advent of FAP inhibitor (FAPI)-based positron em...
Generalizable preconditioning strategies for MAP PET reconstruction using Poisson likelihood [0.03%]
基于泊松似然的MAP PET重建的通用预处理策略
Matteo N Colombo,Marco Paganoni,Luca Presotto
Matteo N Colombo
Introduction: The positron emission tomography (PET) problem with Poisson log-likelihood is notoriously ill-conditioned. This stems from its dependence on the inverse of the measured counts and the square of the attenuati...
First positronium lifetime imaging with scandium-44 on a long axial field-of-view PET/CT [0.03%]
基于长轴向视野的PET/CT进行正电子素寿命成像研究
Lorenzo Mercolli,William M Steinberger,Pascal V Grundler et al.
Lorenzo Mercolli et al.
Purpose: The physical properties of 44Sc, combined with its imminent clinical application, position it as a prime candidate for in vivo positronium lifetime imaging. In this study, we investigate the count statistics for ...
Case Report: 18F-Fluorocholine PET/CT for detecting brown tumours in patients with hyperparathyroidism: a short case series and literature review [0.03%]
病例报告：18F-氟化胆碱正电子发射断层扫描/X线计算机体层成像检测高血钙症患者褐色瘤的临床价值：短期病例系列及文献综述
J Zhang-Yin,Emmanouil Panagiotidis
J Zhang-Yin
Introduction: Brown tumours (BTs), also known as osteitis fibrosa cystica, are benign osteolytic lesions associated with hyperparathyroidism (HPT). BTs are cured by correcting the hypercalcaemia and HPT, which often requi...
Mario Petretta
Mario Petretta
PET/CT imaging of bone disorders in dysparathyroidism: a comprehensive review [0.03%]
特发性甲状旁腺功能紊乱骨病的正电子发射断层扫描/计算机体层摄影检查：系统综述
E Panagiotidis,G Angelidis,V Valotassiou et al.
E Panagiotidis et al.
Parathyroid disorders profoundly affect bone metabolism, often long before structural damage is apparent on conventional imaging. Positron emission tomography/computed tomography (PET/CT) has emerged as a transformative tool in dysparathyro...
Production of 64Cu and 67Cu with accelerator neutrons by deuterons and their separation from zinc [0.03%]
加速中子生产64Cu和67Cu并从锌中分离它们
Yasuki Nagai,Masako Kawabata,Hideya Saeki et al.
Yasuki Nagai et al.
The 64Cu/67Cu pair is an ideal set of theranostic radionuclides for treating patients based on their genetic profiles. We propose a novel production route for this radionuclide pair using accelerator-generated neutrons. We report experiment...
Population pharmacokinetic modeling in radiopharmaceutical therapy: a review [0.03%]
放射药物治疗的群体药代动力学模型研究进展回顾
Deni Hardiansyah,Bisma Barron Patrianesha,Gerhard Glatting
Deni Hardiansyah
Population pharmacokinetic (PopPK) has emerged as a robust framework for characterizing inter-individual variability in the absorbed dose estimates in radiopharmaceutical therapy (RPT). By enabling the analysis of biokinetic data from heter...
Fast PET reconstruction with variance reduction and prior-aware preconditioning [0.03%]
一种基于降方差和先验预处理的快速PET重建方法
Matthias J Ehrhardt,Zeljko Kereta,Georg Schramm
Matthias J Ehrhardt
We investigated subset-based optimization methods for positron emission tomography (PET) image reconstruction incorporating a regularizing prior. PET reconstruction methods that use a prior, such as the relative difference prior (RDP), are ...
Platinum group metals for nuclear medicine, a luxurious dream or the future of imaging and therapy: a review [0.03%]
核医学中的贵金属：奢华的梦还是影像和治疗的未来？综述文章
Daniel G Racz,Ivis F Chaple
Daniel G Racz
Platinum group metals (PGMs) consist of six transition metals: platinum (Pt), palladium (Pd), rhodium (Rh), osmium (Os), iridium (Ir), and ruthenium (Ru). PGMs have been used notably in industrial, electronic, and medical applications. For ...