Gallium-68 fibroblast activation protein inhibitor positron emission tomography in cardiovascular disease [0.03%]
68镓纤维活化蛋白抑制剂正电子发射断层扫描在心血管病中的应用
Dineo Mpanya,Mike Sathekge,Eric Klug et al.
Dineo Mpanya et al.
Gallium-68 fibroblast activation protein inhibitor [(68Ga)Ga-FAPI] is a new radiopharmaceutical positioning itself as the preferred agent in patients with malignant tumours, competing with 2-Deoxy-2-[18F]fluoro-d-glucose [2-(18F)FDG] using ...
Tumor microenvironment and fibroblast activation protein inhibitor (FAPI) PET: developments toward brain imaging [0.03%]
肿瘤微环境和成纤维细胞活化蛋白抑制剂(PAPI)PET：朝向脑部成像的发展
Mehdi Djekidel,Rahaf Alsadi,Maya Abi Akl et al.
Mehdi Djekidel et al.
Fibroblast activation protein (FAP) is a type-II membrane bound glycoprotein specifically expressed by activated fibroblasts almost exclusively in pathological conditions including arthritis, fibrosis and cancer. FAP is overexpressed in can...
Multicentric 68Ga-PSMA PET radiomics for treatment response assessment of 177Lu-PSMA-617 radioligand therapy in patients with metastatic castration-resistant prostate cancer [0.03%]
使用68Ga-PSMA PET影像组学评估177Lu-PSMA-617放射配体治疗转移性去势抵抗性前列腺癌的疗效
Robin Gutsche,Gizem Gülmüs,Felix M Mottaghy et al.
Robin Gutsche et al.
Objective: The treatment with 177Lutetium PSMA (177Lu-PSMA) in patients with metastatic castration-resistant prostate cancer (mCRPC) has recently been approved by the FDA and EMA. Since treatment success is highly variabl...
Automatic deep learning method for third lumbar selection and body composition evaluation on CT scans of cancer patients [0.03%]
用于癌症患者CT扫描的自动深度学习腰3椎选择和体成分评价方法
Lidia Delrieu,Damien Blanc,Amine Bouhamama et al.
Lidia Delrieu et al.
Introduction: The importance of body composition and sarcopenia is well-recognized in cancer patient outcomes and treatment tolerance, yet routine evaluations are rare due to their time-intensive nature. While CT scans pr...
The Application of in silico Methods for Prediction of Blood-Brain Barrier Permeability of Small Molecule PET Tracers [0.03%]
基于计算机的血脑屏障通透性预测方法在小分子PET显影剂中的应用研究进展
E Johanna L Stéen,Danielle J Vugts,Albert D Windhorst
E Johanna L Stéen
Designing positron emission tomography (PET) tracers for targets in the central nervous system (CNS) is challenging. Besides showing high affinity and high selectivity for their intended target, these tracers have to be able to cross the bl...
Leveraging law and ethics to promote safe and reliable AI/ML in healthcare [0.03%]
利用法律和伦理促进医疗保健中安全可靠的AI/ML
Katherine Drabiak
Katherine Drabiak
Artificial intelligence and machine learning (AI/ML) is poised to disrupt the structure and delivery of healthcare, promising to optimize care clinical care delivery and information management. AI/ML offers potential benefits in healthcare,...
F-18 Fluoro-2-Deoxyglucose Positron Emission Tomography (PET)/Computed Tomography (CT) Imaging in Melanoma: Normal Variants, Pitfalls, and Artifacts [0.03%]
18氟脱氧葡萄糖正电子发射断层/计算机体层成像（FDG PET/CT）在黑色素瘤中的应用：正常变异、陷阱及伪影
Jaleelat I Momodu,Mboyo Di Tamba Vangu
Jaleelat I Momodu
Multimodality imaging has revolutionized diagnostic imaging for several oncologic pathologies including melanoma. Although F-18 fluoro-2-deoxyglucose positron emission tomography/ computed tomography [18F]FDG PET/CT has a high sensitivity i...
Ki67 Immunohistochemical Expression Level ≥70%, Bulky Presentation ≥7.5 cm, Meningeal Lymphomatosis, and Interim PET ΔSUVmax After 4 Treatment Cycles <71% as Parts of a Practical Scoring System to Predict Progression-Free Survival and Overall Survival in Diffuse Large B-Cell Lymphoma [0.03%]
Ki67免疫组化表达水平≥70%，肿瘤负荷较大（≥7.5cm），脑膜淋巴瘤综合症，以及4个疗程后的 interim PET ΔSUVmax变化值
Vincent Rebière,Meriem Maajem,Ronan Le Calloch et al.
Vincent Rebière et al.
Currently, prognostic models in diffuse large B-cell lymphoma (DLBCL) fail to closely reflect patients' biological, clinical, and survival heterogeneity. We, therefore, assessed the impact of clinical, biological, immunohistochemical (IHC),...
Normal Variants, Pitfalls and Artifacts in Ga-68 DOTATATE PET/CT Imaging [0.03%]
Ga-68 DOTATATE PET/CT显像的正常变异、陷阱及伪影
Nico Malan,Mboyo-Di-Tamba Vangu
Nico Malan
Indium 111 DTPA Octreotide (Octreoscan) has been the pillar of Somatostatin receptor (SSTRs) imaging in nuclear medicine for over three decades. The advent of PET/CT brought new analogs of somatostatin that have higher affinity and improved...