Stéphane Hazebrouck,Nicole Canon,Stephen C Dreskin
Stéphane Hazebrouck
Allergens are antigens that generate an IgE response (sensitization) in susceptible individuals. The allergenicity of an allergen can be thought of in terms of its ability to sensitize as well as its ability to cross-link IgE/IgE receptor c...
Overview of SERPING1 Variations Identified in Hungarian Patients With Hereditary Angioedema [0.03%]
匈牙利遗传性血管水肿患者的SERPING1变异概述
Edina Szabó,Dorottya Csuka,Noémi Andrási et al.
Edina Szabó et al.
Background: Hereditary angioedema (HAE) due to C1-inhibitor (C1-INH) deficiency (C1-INH-HAE) is a rare autosomal dominant disorder, characterized by recurrent, unpredictable edematous symptoms involving subcutaneous, and/...
Allyssa Phelps,Kelly Bruton,Emily Grydziuszko et al.
Allyssa Phelps et al.
A series of landmark studies have provided conclusive evidence that the early administration of food allergens dramatically prevents the emergence of food allergy. One of the greatest remaining challenges is whether patients with establishe...
Pregnancy in Patients With Hereditary Angioedema and Normal C1 Inhibitor [0.03%]
C1酯酶抑制剂正常的遗传性血管水肿患者的妊娠状况
Natalia Gabriel,Fernanda Marcelino,Mariana P L Ferriani et al.
Natalia Gabriel et al.
Background: HAE with normal C1 inhibitor (HAE-nC1-INH) has been identified as a bradykinin mediated angioedema. Estrogens are one of the main trigger factors. Pregnancy in HAE with C1 inhibitor deficiency showed variable ...
Alba Sánchez Montalvo,Sophie Gohy,Philippe Rombaux et al.
Alba Sánchez Montalvo et al.
Chronic upper airway inflammation is amongst the most prevalent chronic disease entities in the Western world with prevalence around 30% (rhinitis) and 11% (rhinosinusitis). Chronic rhinitis and rhinosinusitis may severely impair the qualit...
Study of Cat Allergy Using Controlled Methodology-A Review of the Literature and a Call to Action [0.03%]
受控方法研究猫过敏-文献回顾及行动呼吁
Lubnaa Hossenbaccus,Sophia Linton,Rashi Ramchandani et al.
Lubnaa Hossenbaccus et al.
The prevalence of cat allergen-induced AR is increasing worldwide, prompting its study using controlled methodology. Three general categories of allergen exposure models currently exist for the study of cat allergen-induced AR: natural expo...
Venom Immunotherapy and Aeroallergen Immunotherapy: How Do Their Outcomes Differ? [0.03%]
毒液免疫疗法与空气过敏原免疫疗法的区别及其疗效差异？
Cristoforo Incorvaia,Erminia Ridolo,Marina Mauro et al.
Cristoforo Incorvaia et al.
Allergen immunotherapy (AIT) and venom immunotherapy (VIT) are meant to work on the causes of allergies, respectively, to respiratory allergens and Hymenoptera venom, inducing tolerance to the allergens and modifying the natural history of ...
Patterns of allergic sensitization and factors associated with emergence of sensitization in the rural tropics early in the life course: findings of an Ecuadorian birth cohort [0.03%]
过敏原特异性的模式及生命早期热带农村过敏原特异性出现的相关因素：一项来自厄瓜多尔的出生队列研究
Philip J Cooper,Irina Chis Ster,Martha E Chico et al.
Philip J Cooper et al.
Introduction: There are limited data on emergence of allergic sensitization (or atopy) during childhood in tropical regions. Methods: W...
β-Glucosylceramide From Allergic Mothers Enhances Offspring Responsiveness to Allergen [0.03%]
过敏母亲来源的β-岩藻糖甘油酯可增强后代对过敏原的反应性
Matthew T Walker,Ryan P Ferrie,Aki Hoji et al.
Matthew T Walker et al.
In animals and humans, offspring of allergic mothers have increased responsiveness to allergen and the allergen-specificity of the offspring can be different than that of the mother. In our preclinical models, the mother's allergic response...
Erik D Anderson,Mohammadali E Alishahedani,Ian A Myles
Erik D Anderson
Atopic diseases, particularly atopic dermatitis (AD), asthma, and allergic rhinitis (AR) share a common pathogenesis of inflammation and barrier dysfunction. Epithelial to mesenchymal transition (EMT) is a process where epithelial cells tak...