Antigen Uptake After Intradermal Microinjection Depends on Antigen Nature and Formulation, but Not on Injection Depth [0.03%]
皮内微注射的抗原摄取依赖于抗原本身的性质和配方，不依赖于注射深度
Romain J T Leboux,Pim Schipper,Toni M M van Capel et al.
Romain J T Leboux et al.
The skin is an attractive alternative administration route for allergy vaccination, as the skin is rich in dendritic cells (DCs) and is easily accessible. In the skin multiple subsets of DCs with distinct roles reside at different depths. I...
Aeroallergens and Climate Change in Tulsa, Oklahoma: Long-Term Trends in the South Central United States [0.03%]
俄克拉荷马州图尔萨的花粉与气候变化：美国中南部地区的长期趋势
Estelle Levetin
Estelle Levetin
Climate change is having a significant effect on many allergenic plants resulting in increased pollen production and shifts in plant phenology. Although these effects have been well-studied in some areas of the world, few studies have focus...
Editorial: Activation of Innate Immunity by Allergens and Allergenic Sources [0.03%]
编辑部：过敏原及其过敏性来源引发先天免疫反应
Fatima Ferreira,Geoffrey A Mueller,Stefanie Gilles et al.
Fatima Ferreira et al.
Luis Caraballo
Luis Caraballo
Nicole F Brackett,Anna Pomés,Martin D Chapman
Nicole F Brackett
Genome engineering with clustered regularly interspaced short palindromic repeats (CRISPR) technology offers the unique potential for unequivocally deleting allergen genes at the source. Compared to prior gene editing approaches, CRISPR boa...
Patricia Román-Carrasco,Wolfgang Hemmer,Alejandro Cabezas-Cruz et al.
Patricia Román-Carrasco et al.
The α-Gal syndrome is a complex allergic disease characterized by the development of specific IgE antibodies against the carbohydrate galactose-α-1,3-galactose (α-Gal), an oligosaccharide present in cells and tissues of non-primate mamma...
The COMPARE Database: A Public Resource for Allergen Identification, Adapted for Continuous Improvement [0.03%]
COMPARE数据库：一个用于过敏原识别的公共资源，并不断改进
Ronald van Ree,Dexter Sapiter Ballerda,M Cecilia Berin et al.
Ronald van Ree et al.
Motivation: The availability of databases identifying allergenic proteins via a transparent and consensus-based scientific approach is of prime importance to support the safety review of genetically-modified foods and feeds, and public safe...
Influence of the Microbiome on Chronic Rhinosinusitis With and Without Polyps: An Evolving Discussion [0.03%]
微生物组对有无鼻息肉慢性鼻窦炎的影响：一个不断发展的讨论
Kyle S Huntley,Joshua Raber,Lauren Fine et al.
Kyle S Huntley et al.
Chronic rhinosinusitis (CRS) is widely prevalent within the population and often leads to decreased quality of life, among other related health complications. CRS has classically been stratified by the presence of nasal polyps (CRSwNP) or t...
The Rhinobiome of Exacerbated Wheezers and Asthmatics: Insights From a German Pediatric Exacerbation Network [0.03%]
儿童喘息加重的鼻腔微生物群：来自德国儿科加重网络的新见解
Malik Aydin,Cornelius Weisser,Olivier Rué et al.
Malik Aydin et al.
Although the nose, as a gateway for organism-environment interactions, may have a key role in asthmatic exacerbation, the rhinobiome of exacerbated children with asthma was widely neglected to date. The aim of this study is to understand th...
The Challenge of Home Allergen Re-introductions Using the Ladder Approach in Children With Non-IgE Mediated Gastrointestinal Food Allergy [0.03%]
阶梯法治疗的非IgE介导的胃肠过敏患儿居家过敏原再暴露的挑战
Rosan Meyer,Claire De Koker,Robert Dziubak et al.
Rosan Meyer et al.
Background: Oral food challenges remain the most reliable method for allergy confirmation. Although consensus guidelines have been published to unify Immunoglobulin E (IgE)-mediated challenges, this does not exist for non-IgE mediated gastr...