Olivia J Ly Lesslar,Peter K Smith
Olivia J Ly Lesslar
Itch is a nociceptive sensation linked with reflexes and cognitive motor actions. We traditionally think of itch as a sensation of the skin related to allergy, an insect sting or interestingly, anxiety and frustration. Less understood and c...
Estimating the Risk of Severe Peanut Allergy Using Clinical Background and IgE Sensitization Profiles [0.03%]
基于临床背景和IgE谱型估计严重花生过敏的风险
Mareen R Datema,Sarah A Lyons,Montserrat Fernández-Rivas et al.
Mareen R Datema et al.
Background: It is not well-understood why symptom severity varies between patients with peanut allergy (PA). Objective: To gain insight into the clinical profile of subjects with mild-to-moderate and severe PA, and investigate individual an...
Birch Pollen Induces Toll-Like Receptor 4-Dependent Dendritic Cell Activation Favoring T Cell Responses [0.03%]
白桦树花粉诱导Toll样受体4依赖性的树突状细胞活化促进T细胞的反应
Lisa Pointner,Amin Kraiem,Michael Thaler et al.
Lisa Pointner et al.
Seasonal exposure to birch pollen (BP) is a major cause of pollinosis. The specific role of Toll-like receptor 4 (TLR4) in BP-induced allergic inflammation and the identification of key factors in birch pollen extracts (BPE) initiating this...
Diet Diversity Through the Life-Course as an Opportunity Toward Food Allergy Prevention [0.03%]
生命周期中的饮食多样性是预防食物过敏的机会
Giulia C I Spolidoro,Domenico Azzolino,Matteo Cesari et al.
Giulia C I Spolidoro et al.
The prevalence of food allergies (FA) is increasing worldwide. Generally, the onset of allergies, including FA, begins in early childhood and may persist and/or develop through the life-course. Even though epidemiological studies have focus...
Asthma Phenotypes and Host Risk Factors Associated With Various Asthma-Related Outcomes in Health Workers [0.03%]
医护人员不同哮喘结局相关的表型和宿主危险因素
Hussein H Mwanga,Roslynn Baatjies,Tanusha Singh et al.
Hussein H Mwanga et al.
Background: Work-related asthma phenotypes in health workers (HWs) exposed to cleaning agents have not been investigated extensively as other occupational exposures. This study aimed to describe asthma phenotypes and to identify important h...
Kyoung Yong Jeong,Jung-Won Park
Kyoung Yong Jeong
Allergen repertoire should reflect the region's climate, flora, and dining culture to allow for a better diagnosis. In Korea, tree pollens of oak and birch in the spring in conjunction with weed pollens of mugwort, ragweed, and Japanese hop...
Proteomics Profiling to Distinguish DOCK8 Deficiency From Atopic Dermatitis [0.03%]
蛋白质组学谱分析鉴别DOCK8缺陷和特应性皮炎
Minnie Jacob,Afshan Masood,Zakiya Shinwari et al.
Minnie Jacob et al.
Dedicator of cytokinesis 8 deficiency is an autosomal recessive primary immune deficiency disease belonging to the group of hyperimmunoglobulinemia E syndrome (HIES). The clinical phenotype of dedicator of cytokinesis 8 (DOCK8) deficiency, ...
Component-Resolved Diagnosis of American Cockroach (Periplaneta americana) Allergy in Patients From Different Geographical Areas [0.03%]
不同地区的患者对美洲蟑螂（美洲大蠊）的组分解析诊断
Andrea Wangorsch,Annette Jamin,Stephanie Eichhorn et al.
Andrea Wangorsch et al.
Background: Manifestation of respiratory allergy to American cockroach (Periplaneta americana) is prominent in the subtropical and tropical areas. However, co-existing perennial indoor inhalant allergies frequently compromise clinical diagn...
A First Pre-season Pollen Transport Climatology to Bavaria, Germany [0.03%]
德国巴伐利亚州首次 preseason 花粉传输气候学研究
Annette Menzel,Homa Ghasemifard,Ye Yuan et al.
Annette Menzel et al.
Climate impacts on the pollen season are well-described however less is known on how frequently atmospheric transport influences the start of the pollen season. Based on long-term phenological flowering and airborne pollen data (1987-2017) ...
Translational Analysis of Moderate to Severe Asthma GWAS Signals Into Candidate Causal Genes and Their Functional, Tissue-Dependent and Disease-Related Associations [0.03%]
中重度哮喘GWAS信号的转录组学分析及候选因果基因的功能、组织依赖性和疾病相关性研究
Michael A Portelli,Kamini Rakkar,Sile Hu et al.
Michael A Portelli et al.
Asthma affects more than 300 million people globally and is both under diagnosed and under treated. The most recent and largest genome-wide association study investigating moderate to severe asthma to date was carried out in 2019 and identi...