Hannes Nösslinger,Ewald Mair,Gertie J Oostingh et al.
Hannes Nösslinger et al.
Background: The increasing prevalence of allergic diseases, along with their diagnosis and treatment, presents a growing challenge in health care. To reduce this burden, a highly sensitive and specific point-of-care test ...
Risk factors for angiotensin converting enzyme inhibitor angioedema in a South African population [0.03%]
南非人口中血管紧张素转换酶抑制剂引起的血管性水肿的风险因素
Cascia Day,Lovemore Mapahla,Melissa Ribeiro et al.
Cascia Day et al.
Introduction: Angiotensin converting enzyme inhibitors (ACEI) have proven mortality and morbidity benefit in hypertension, ischemic heart disease, heart failure, and renal disease and are among the most prescribed medicat...
Pre-diagnostic and non-advanced systemic mastocytosis without cutaneous involvement have an increased risk of anaphylaxis [0.03%]
无皮肤受累的前驱期和非晚期系统性mastocytosis伴有较高的过敏性休克风险
Andrea Sangalli,Valerio Pravettoni,Mariarita Sciumè et al.
Andrea Sangalli et al.
Background: Patients with mastocytosis have a higher risk of anaphylactic reactions. This study aims to assess the prevalence and risk factors of anaphylaxis among patients diagnosed with Systemic Mastocytosis (SM), inclu...
Duong Duc Pham,Tae-Bum Kim
Duong Duc Pham
Introduction: Airway epithelial cells function as the first physical barrier against pathogens and are key regulators of immune responses by producing a wide array of cytokines involved in both innate and adaptive immunit...
Nasal saline irrigation with azelastine-fluticasone nasal spray in moderate-to-severe persistent allergic rhinitis: a randomized controlled trial [0.03%]
生理盐水冲洗联合azelastine-fluticasone鼻喷雾剂治疗中重度持续性过敏性鼻炎：随机对照试验
Song Li,Rui Xu,Shaoqing Yu et al.
Song Li et al.
Background: Symptom control in patients with moderate-to-severe persistent allergic rhinitis (PAR) who remain inadequately controlled on intranasal corticosteroid monotherapy remains challenging, highlighting the urgent n...
Clinical Trial
Frontiers in allergy. 2025 Oct 13:6:1622510. DOI:10.3389/falgy.2025.1622510 2025
Use of oral corticosteroids in patients with asthma: how far is clinical practice from the guidelines? Results from surveys of patients and doctors [0.03%]
哮喘患者的口服皮质激素使用情况：临床实践与指南的差距有多大？患者和医生调查结果
Luisa Brussino,Gianna Camiciottoli,Annalisa Stassaldi et al.
Luisa Brussino et al.
Introduction: Asthma is often treated with oral corticosteroids (OCS), despite their association with significant adverse effects. While guidelines recommend minimizing OCS use through alternative therapies and patient-ce...
Real-life evaluation of the effectiveness of biologics for chronic rhinosinusitis with nasal polyps in Europe: a Delphi study to define key variables for the INVENT registry [0.03%]
欧洲生物制剂治疗慢性鼻窦炎伴鼻息肉有效性的真实世界评估：INVENT登记处纳入关键变量的德尔菲研究
Vibeke Backer,Eugenio De Corso,Geoffrey Mortuaire et al.
Vibeke Backer et al.
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent inflammatory condition often associated with type 2 inflammation. While biologics are a promising treatment for patients with uncontrolled CRSw...
Case Report: Not all recurrent "idiopathic" anaphylaxis is idiopathic [0.03%]
个例报告：并非所有复发性「特发性」过敏反应都是特发性的
Sally Mahgoub Khalil,Sherin Rahim,Hassan Mobayed et al.
Sally Mahgoub Khalil et al.
Introduction: Anaphylaxis is the most severe manifestation of systemic immediate hypersensitivity, yet the underlying trigger often remains elusive. When routine history and allergy testing fail to identify a cause, the c...
The roles of serum Th1, Th2, and Th17 cytokines in patients with chronic urticaria: a systematic review and meta-analysis [0.03%]
慢性自发性荨麻疹患者血清Th1、Th2和Th17细胞因子作用的系统评价和meta分析
Jingwen Xue,Chinghsuan Sun,Mai Shi et al.
Jingwen Xue et al.
Objectives: To conduct a systematic review and meta-analysis to identify Th1-, Th2, and Th17 related serum biomarkers that reflect disease activity in chronic urticaria (CU), thereby enhancing the assessment of disease ac...
Machine learning-derived genetic risk scores identify IL21 as a predictor of response to omalizumab and dupilumab in asthma [0.03%]
机器学习衍生的遗传风险评分可识别IL21作为哮喘患者对奥马珠单抗和度普利尤单抗治疗反应的预测因子
Ayobami Akenroye,Chengyue Zhang,Tanawin Nopsopon et al.
Ayobami Akenroye et al.
Rationale: Genetic risk scores (GRS) of Th1/2/17-related loci may be associated with response to biologics. We leveraged previously published machine learning-derived GRSs associated with plasma proteins from the INTERVAL...