Mechanisms for Alternaria alternata Function in the Skin During Induction of Peanut Allergy in Neonatal Mice With Skin Barrier Mutations [0.03%]
表皮屏障缺陷的新生小鼠诱导花生过敏反应时Alternaria alternata的作用机制研究
Lauren M Buelow,Akihiko Hoji,Kiet Tat et al.
Lauren M Buelow et al.
Neonatal mice with heterozygous mutations in genes encoding the skin barrier proteins filaggrin and mattrin (flaky tail mice [FT+/-]) exhibit oral peanut-induced anaphylaxis after skin sensitization. As we have previously reported, sensitiz...
Recurrent Wheeze Exacerbations Following Acute Bronchiolitis-A Machine Learning Approach [0.03%]
急性支气管炎后的反复喘息发作-一种机器学习方法
Heidi Makrinioti,Paraskevi Maggina,John Lakoumentas et al.
Heidi Makrinioti et al.
Introduction: Acute bronchiolitis is one of the most common respiratory infections in infancy. Although most infants with bronchiolitis do not get hospitalized, infants with hospitalized bronchiolitis are more likely to develop wheeze exace...
Bettina Wedi
Bettina Wedi
Rik J L van der Lans,Wytske J Fokkens,Sietze Reitsma
Rik J L van der Lans
Patients with non-steroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (N-ERD) often suffer from chronic rhinosinusitis (CRS) with nasal polyps, a form of primary diffuse Type 2 CRS. Although this disease is also seen in...
Non-atopic Neonatal Thymic Innate Lymphoid Cell Subsets (ILC1, ILC2, and ILC3) Identification and the Modulatory Effect of IgG From Dermatophagoides Pteronyssinus (Derp)-Atopic Individuals [0.03%]
非特异性新生儿胸腺固有淋巴样细胞亚群（ILC1、ILC2和ILC3）的鉴定及屋尘螨（Derp）过敏个体IgG的调节作用
Thamires Rodrigues de Sousa,Fábio da Ressureição Sgnotto,Beatriz Oliveira Fagundes et al.
Thamires Rodrigues de Sousa et al.
Innate lymphoid cells (ILCs) are classified into distinct subsets termed ILC1, ILC2, and ILC3 cells. The existing literature lacks evidence identifying ILCs and their subsets in the human thymus but already demonstrates that they can exert ...
Annina Lyly,Tanya M Laidlaw,Marie Lundberg
Annina Lyly
The pathomechanisms behind NSAID-exacerbated respiratory disease are complex and still largely unknown. They are presumed to involve genetic predisposition and environmental triggers that lead to dysregulation of fatty acid and lipid metabo...
Der p 1 Disrupts the Epithelial Barrier and Induces IL-6 Production in Patients With House Dust Mite Allergic Rhinitis [0.03%]
屋尘螨过敏性鼻炎患者中派白细胞趋化因子2破坏上皮屏障并诱导白细胞介素6产生
Kazuhiro Ogi,Mahnaz Ramezanpour,Sha Liu et al.
Kazuhiro Ogi et al.
Background: Dermatophagoides pteronyssinus 1/2 (Der p 1/Der p 2) are regarded as important allergens of house dust mite (HDM). However, the effect of both products on the epithelial barrier and immune response of patients with and without H...
Home-Based Peanut Oral Immunotherapy for Low-Risk Peanut-Allergic Preschoolers During the COVID-19 Pandemic and Beyond [0.03%]
新冠肺炎疫情期间及以后居家口服免疫疗法治疗低风险花生过敏学龄前儿童
Gilbert T Chua,Edmond S Chan,Lianne Soller et al.
Gilbert T Chua et al.
The coronavirus disease 2019 (COVID-19) pandemic has led to the deprioritization of non-emergency services, such as oral food challenges and the initiation of oral immunotherapy (OIT) for food-allergic children. Recent studies have suggeste...
Matricellular Protein Periostin Promotes Pericyte Migration in Fibrotic Airways [0.03%]
基质细胞蛋白periostin促进纤维化气道周细胞迁移
Rebecca E Bignold,Jill R Johnson
Rebecca E Bignold
Introduction: Periostin is a matricellular protein that is currently used as a biomarker for asthma. However, its contribution to tissue remodeling in allergic asthma is currently unknown. We have previously demonstrated that tissue-residen...
Long-Term Pollen Monitoring in the Benelux: Evaluation of Allergenic Pollen Levels and Temporal Variations of Pollen Seasons [0.03%]
比利时荷兰卢森堡地区长期花粉监测：致敏性花粉浓度和花粉期时间变化的评估
Letty A de Weger,Nicolas Bruffaerts,Mieke M J F Koenders et al.
Letty A de Weger et al.
Airborne pollen is a major cause of allergic rhinitis, affecting between 10 and 30% of the population in Belgium, the Netherlands, and Luxembourg (Benelux). Allergenic pollen is produced by wind pollinating plants and released in relatively...